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  • 1
    ISSN: 1741-0444
    Keywords: Cancer ; Hyperthermia ; Programmable calculator
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The use of whole-body hyperthermia as an adjuvant mode of therapy for metastatic cancer requires an accurate control of core body temperature so that the high temperatures encountered during treatment may be safely employed. Heating of the patient is accomplished by use of high-perfusion water-heated blankets. The temperature of the water circulating through the blankets is regulated by digital feedback control, using patient oesophageal temperature as a reference. A forced air heat exchanger is used to cool the circulating water once the control temperature is reached. Patient core body temperatures are currently being maintained at 41·8°C±0·1°C for time periods of up to four hours.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2017-03-23
    Description: The Danakil region of northern Afar is an area of ongoing seismic and volcanic activity caused by the final stages of continental breakup. To improve the quantification of seismicity, we developed a calibrated local earthquake magnitude scale. The accurate calculation of earthquake magnitudes allows the estimation of b -values and maximum magnitudes, both of which are essential for seismic-hazard analysis. Earthquake data collected between February 2011 and February 2013 on 11 three-component broadband seismometers were analyzed. A total of 4275 earthquakes were recorded over hypocentral distances ranging from 0 to 400 km. A total of 32,904 zero-to-peak amplitude measurements ( A ) were measured on the seismometer’s horizontal components and were incorporated into a direct linear inversion that solved for all individual local earthquake magnitudes ( M L ), 22 station correction factors ( C ), and 2 distance-dependent factors ( n , K ) in the equation M L =log( A )–log( A 0 )+ C . The resultant distance correction term is given by –log( A 0 )=1.274336log( r /17)–0.000273( r –17)+2. This distance correction term suggests that attenuation in the upper and mid-crust of northern Afar is relatively high, consistent with the presence of magmatic intrusions and partial melt. In contrast, attenuation in the lower crust and uppermost mantle is anomalously low, interpreted to be caused by a high melt fraction causing attenuation to occur outside the seismic frequency band. The calculated station corrections serve to reduce the M L residuals significantly but do not show a correlation with regional geology. The cumulative seismicity rate produces a b -value of 0.9±0.06, which is higher than most regions of continental rifting yet lower than values recorded at midocean ridges, further supporting the hypothesis that northern Afar is transitioning to seafloor spreading. Electronic Supplement: List of all local earthquakes used in the study with calculated local magnitudes and associated magnitude error.
    Print ISSN: 0037-1106
    Electronic ISSN: 1943-3573
    Topics: Geosciences , Physics
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