Publication Date:
2015-09-26
Description:
Article Some patients with HIV-associated tuberculosis develop an immune reconstitution inflammatory syndrome (TB-IRIS) in response to antiretroviral therapy. Here the authors identify genes differentially expressed in patients likely to progress to TB-IRIS and find activation of Toll-like receptor and inflammasome pathways. Nature Communications doi: 10.1038/ncomms9451 Authors: Rachel P. J. Lai, Graeme Meintjes, Katalin A. Wilkinson, Christine M. Graham, Suzaan Marais, Helen Van der Plas, Armin Deffur, Charlotte Schutz, Chloe Bloom, Indira Munagala, Esperanza Anguiano, Rene Goliath, Gary Maartens, Jacques Banchereau, Damien Chaussabel, Anne O’Garra, Robert J. Wilkinson
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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