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  • Articles  (2)
  • RNA-replication  (1)
  • hydration  (1)
  • Springer  (2)
  • EMBO Press
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Monatshefte für Chemie 113 (1982), S. 237-263 
    ISSN: 1434-4475
    Keywords: Polymerization kinetics ; Quasiequilibrium ; RNA-replication
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Ein vereinfachter Mechanismus derRNA-Replikation durch eine spezifische Polymerase wird durch direkte numerische Integration und mit Hilfe der Annahme von „Quasigleichgewicht“ analysiert. Die Quasigleichgewichtsannahme wird an Hand von drei Beispielen einfacher Zweistufenreaktionen mathematisch definiert. Die drei Beispiele beschreiben: (1) die Annäherung an den Gleichgewichtszustand, (2) den irreversiblen Abbau und (3) das unbeschränkte Wachstum einer Verbindung.
    Notes: Abstract A simplified mechanism ofRNA-replication by a specific polymerase is analysed by direct numerical integration and by means of the “quasiequilibrium approximation”. The quasiequilibrium approximation is formulated in precise mathematical terms for three simple, two step reactions which describe approach towards equilibrium, irreversible transformation and unlimited growth.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1327
    Keywords: Key words Metalloenzymes ; Nuclear magnetic resonance ; Aromatic compounds ; biodegradation ; hydration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract  Water proton T 1 –1 measurements at magnetic fields between 0.01 and 50 MHz [nuclear magnetic relaxation dispersion (NMRD) measurements] have been performed on solutions of phthalate dioxygenase (PDO) reconstituted at the catalytic iron site with copper(II) or manganese(II). The data show evidence of a weakly coordinated water molecule in CuPDO; in the presence of the substrate, phthalate, this water appears to become even less tightly bound, and an additional tightly coordinated water can be detected. In PDO reconstituted with manganese, one tightly coordinated water is detected in the presence and in the absence of phthalate. An attempt is made to reconcile these data with low-temperature near-IR magnetic circular dichroism and X-ray absorption data, which show that PDO reconstituted with iron or cobalt is six-coordinate in the absence of substrate and five-coordinate in the presence of substrate.
    Type of Medium: Electronic Resource
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