ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • pharmacokinetics  (10)
  • Halotydeus destructor  (9)
  • nitrogen  (9)
  • Springer  (28)
  • Copernicus
Collection
Keywords
Publisher
  • Springer  (28)
  • Copernicus
Years
  • 1
    Electronic Resource
    Electronic Resource
    A comparative study of the pharmacokinetics and pharmacodynamics of atenolol, hydrochlorothiazide and amiloride in normal young and elderly subjects and elderly hypertensive patients (1987)
    Springer
    European journal of clinical pharmacology 32 (1987), S. 53-60 
    Details
    ISSN: 1432-1041
    Keywords: atenolol ; amiloride ; hydrochlorothiazide ; young ; elderly ; pharmacokinetics ; pharmacodynamics ; volunteers ; patients ; hypertension
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Six normal young and six normal elderly volunteers and six elderly hypertensive patients took part in an acute and chronic dose study of a combination capsule containing atenolol (50 mg), hydrochlorothiazide (25 mg) and amiloride (2.5 mg) designed for the treatment of hypertension. No difference in any of the drug pharmacokinetic parameters could be detected between the hypertensives and the normal elderly subjects. The bio-availability and the 24-h blood concentrations of all three drugs, half-life of atenolol and amiloride and the peak concentration of hydrochlorothiazide was significantly greater in the elderly. The 24-h blood concentrations of atenolol and hydrochlorothiazide did not alter with chronic dosing, but amiloride concentrations were significantly higher at this time in all groups. A significant fall in the blood pressure was observed in the hypertensive group. Heart rate fell more in the normal and hypertensive elderly subjects than in the young. The combination has shown to be an effective and well tolerated antihypertensive in the elderly patient with a 24-h duration of action.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00609957
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Pharmacokinetics and protein binding of methocarbamol in renal insufficiency and normals (1990)
    Springer
    European journal of clinical pharmacology 39 (1990), S. 193-194 
    Details
    ISSN: 1432-1041
    Keywords: methocarbamol ; haemodialysis ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary We determined plasma methocarbamol concentrations over 24 h following a 1.5 g methocarbamol dose (off-dialysis day) to 8 chronic haemodialysis patients and compared these results to those from 17 healthy male volunteers. The harmonic mean elimination half-life was similar between the two groups, 1.24 and 1.14 h, respectively. tmax and the weight-adjusted Cmax were 1.1 h and 27.0 mg · m−1 for haemodialysis patients and 1.1 and 23.1 mg · l−1 for normals. Relative systemic availability was assessed by comparing weight-normalized AUC × k10 products. These results indicate no significant differences with respect to methocarbamol absorption, with the relative systemic availability in patients being 113%. These data suggest that absorption and elimination of methocarbamol is similar between normal subjects and patients undergoing maintenance haemodialysis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00280060
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Antixenotic resistance of subterranean clover cotyledons to redlegged earth mite, Halotydeus destructor (1996)
    Springer
    Entomologia experimentalis et applicata 79 (1996), S. 161-169 
    Details
    ISSN: 1570-7458
    Keywords: mites ; Halotydeus destructor ; resistance ; antixenosis ; feeding ; toughness ; Trifolium subterraneum ; Acarina ; Penthaleidae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The short-term response of redlegged earth mite, Halotydeus destructor (Tucker) (Acarina: Penthaleidae) to cotyledons of different varieties of subterranean clover (Trifolium subterraneum subsp. subterraneum L.) was assessed by means of paired choice tests, and no-choice tests. H. destructor had lower numbers and fed less on detached cotyledons of resistant than susceptible varieties, yielding a correlation between the numbers of mites and feeding damage to the cotyledons during a three hour test period. For a number of resistant and susceptible varieties, there was a negative correlation between cotyledon deterrence in the three hour choice test and feeding damage to seedling after a two week period. Since the response of the mites to different subclover varieties occurred within three hours, it is concluded that the resistance is based on antixenosis. No evidence was obtained for antifeedant activity in organic solvent extracts from the variety DGI007 (resistant) in comparison with those from the variety Dalkeith (susceptible). Water soluble compounds from DGI007 cotyledons were preferred by mites, in feeding tests in terms of numbers, over those from Dalkeith (susceptible). Squeezed sap from the cotyledons of both varieties showed the same effects on mites as 5% glucose and were more phagostimulatory than water extracts. Mechanically damaged cotyledons of Dalkeith and DGI007 attracted more mites than the undamaged counterparts. The toughness of cotyledons in 17 varieties of T. subterraneum subsp. subterraneum was measured with a manual penetrometer. Results showed a negative correlation between toughness values and mite feeding damage scores (r2=0.752) for all varieties except S3615D (resistant). This implies a likely involvement of epidermal toughness as a contributor in the antixenotic resistance of these varieties. Other mechanisms may be involved in the resistance of S3615D.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00343335
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Assays for the effects of volatile compounds from artificially damaged cotyledons of subterranean clover on the redlegged earth mite, Halotydeus destructor (1996)
    Springer
    Experimental and applied acarology 20 (1996), S. 61-72 
    Details
    ISSN: 1572-9702
    Keywords: Assays ; volatile compounds ; Halotydeus destructor ; mite feeding ; subclover cotyledons ; artificial damage
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The effects on the redlegged earth mite (Halotydeus destructor) (Acarina: Penthaleidae) of volatile compounds released from artificially damaged cotyledons of subterranean clover (Trifolium subterraneum L.), a host plant, were investigated with different assays. Mites were repelled by the volatile compounds in flask tube and in trimmed cotyledon disc tests. No differences could be shown between different tissue amounts and between resistant and susceptible varieties. When a membrane sachet was used containing either 2-(E)-hexenal, a compound produced by damaged subclover cotyledons, or the total volatile compounds collected from damaged cotyledons of Dalkeith (susceptible) admixed with 1% glucose, mites gathered to low but were deterred by high concentrations of the compounds. Volatile compounds collected from the resistant variety DGI007 were more deterrent than those from the susceptible Dalkeith. Membrane sachets containing 30 p.p.m. of 2-(E)-hexenal and 1% glucose were less preferred than cotyledons of Dalkeith (susceptible) but were not different from DGI007 (resistant). By increasing the glucose concentration to 5%, the membrane sachets with 30 p.p.m. of 2-(E)-hexenal were preferred to cotyledons of either variety. The results indicate that the membrane feeding technique provides a sensitive way of assaying volatile compounds from damaged subclover cotyledons against the mite.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00051153
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Cold storage of Halotydeus destructor (Acari: Penthaleidae) for use in experiments (2000)
    Springer
    Experimental and applied acarology 24 (2000), S. 123-133 
    Details
    ISSN: 1572-9702
    Keywords: redlegged earth mite ; Halotydeus destructor ; cold storage ; low temperature
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Survival of medium sized nymphal stages of redlegged earth mite Halotydeus destructor (Tucker) (mainly tritonymphs and deutonymphs) stored under low temperature (1.5° C) in sealed plastic boxes remained more than 50% after 12 days of storage, with some mites surviving for up to eight weeks. Adding fresh subclover leaves into the storage box increased the survival rate of mites from 12% to 28%, 19 days after the storage started. Mites stored for two weeks at low temperatures showed feeding activity in a screening experiment similar to mites collected directly from the field. This indicated that cold storage of redlegged earth mite can be used to build up mite numbers for large screening experiments, or to extend the period of availability of mites collected from the field. However, their reproductive ability was greatly reduced after three weeks at low temperature. Thus, care should be taken when using mites for experiments measuring reproduction. The implications of low temperatures for reducing field populations of mites in midwinter are also discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006454621228
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    An improved method for rearing Halotydeus destructor (Acari: Penthaleidae) in the laboratory (1995)
    Springer
    Experimental and applied acarology 19 (1995), S. 337-345 
    Details
    ISSN: 1572-9702
    Keywords: Laboratory rearing ; Halotydeus destructor ; Vicia sativa ; fungal control
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract We developed an improved method for rearing Halotydeus destructor in the laboratory. Mite numbers increased rapidly over the summer of 1992–1993 when fed on vetch, Vicia sativa cv Blanchefleur; in contrast mite numbers were low and fell over the second half of the summer of 1990–91 when fed on subterranean clover, Trifolium subterraneum cv Junee. On V. sativa at a fluctuating temperature from 11 to 18°C 200 mites produced a mean of 1308 and 1455 progeny per transfer in 2 years, a 6–7-fold rate of increase per transfer. The mean transfer time was 35 days and using the interval between transfers as a measure of generation time, the mites completed six to seven generations with no evidence for development of diapause eggs from August until April. There was considerable variability in the numbers of mites produced per pot, associated in part with the presence of Verticillium sp. fungus in 35% of the pots during transfers. Improvement in H. destructor rearing resulted from the use of V. sativa cv Blanchefleur as a food source, maintenance of high humidity and adequate ventilation within cages, and the transfer of mites to fresh food sources at early nymphal stages, which reduced the spread of fungal infections.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00052391
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Correlation of 1-octen-3-one with antixenotic resistance in subterranean clover cotyledons to red-legged earth mite,Halotydeus destructor (Acarina: Penthaleidae) (1996)
    Springer
    Journal of chemical ecology 22 (1996), S. 369-382 
    Details
    ISSN: 1573-1561
    Keywords: Subterranean clover ; Trifolium subterraneum ; cotyledons ; redlegged earth mite ; Halotydeus destructor ; deterrence ; 1-octen-3-one ; volatiles ; host resistance ; antixenosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Artificially damaged cotyledons of subterranean clover (Trifolium subterraneum L.) released several volatile metabolites, including 1-octen-3-one, arising from lipid peroxidation. The amount of 1-octen-3-one produced was negatively correlated with feeding damage caused by the red-legged earth mite (Halotydeus destructor) in nine out of 10 resistant and susceptibleT. subterraneum varieties tested. The EC50 of this compound in deterring mites from feeding in a membrane bioassay was 50 ppm. Cotyledon toughness was also involved in resistance. The resistant variety, S3615D, which has the lowest toughness value among the resistant varieties, produced the highest amount of 1-octen-3-one recovered from the headspace in 1 hr. Artificially damaged cotyledons of both susceptible Dalkeith and resistant DG1007, growing in shade, showed lower toughness, but had enhanced production of C8 volatile compounds and were avoided by mites during a 3-hr feeding test. When both 1-octen-3-one content and cotyledon toughness value were taken as cofactors in resistance, the resultant multiplication value yielded a more significantly negative correlation with mite feeding damage scores within the 10 varieties than either factor alone. We conclude that 1-octen-3-one has a role in resistance of subclover cotyledon to the mite.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02055105
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    The Effect of Volatile Metabolites of Lipid Peroxidation on the Aggregation of Redlegged Earth Mites Halotydeus destructor (Acarina: Penthaleidae) on Damaged Cotyledons of Subterranean Clover (1997)
    Springer
    Journal of chemical ecology 23 (1997), S. 163-174 
    Details
    ISSN: 1573-1561
    Keywords: Subterranean clover ; Trifolium subterraneum ; redlegged earth mite ; Halotydeus destructor ; cotyledons ; attraction ; repellance ; lipid peroxidation products ; volatiles
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Redlegged earth mites (Halotydeus destructor) aggregated in larger numbers on cotyledons of subterranean clover (Trifolium subterraneum L.) previously damaged either by mite feeding or by mechanical injury than on undamaged cotyledons. This effect lasted for up to 7 days. The total volatile fractions derived from crushed cotyledons and its three major components, 2-(E)-hexenal, 1-octen-3-ol, and 1-octen-3-one, were tested for their effect on the aggregation of mites. Significantly more mites gathered on detached cotyledons treated with the metabolites at low concentrations than on controls, with 2-(E)-hexenal being the most effective. Mites were repelled by higher concentrations of the metabolites and 1-octen-3-one, the most active, killed mites at high concentrations. Fewer mites aggregated on DGI007 (resistant) than on Dalkeith (susceptible) cotyledons treated with droplets of the metabolites. The three volatile metabolites were recovered from the headspace of undamaged and of damaged cotyledons. Crushed cotyledons of Dalkeith produced higher levels of 2-(E)-hexenal and lower levels of 1-octen-3-one than undamaged cotyledons. The results suggest that damage-induced metabolites enhance the aggregation of redlegged earth mites at low concentrations and reduce aggregation at high concentrations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/B:JOEC.0000006352.68072.22
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Role of Alkaloids in Resistance of Yellow Lupin to Red-Legged Earth Mite Halotydeus destructor (2000)
    Springer
    Journal of chemical ecology 26 (2000), S. 429-441 
    Details
    ISSN: 1573-1561
    Keywords: Lupinus luteus ; Halotydeus destructor ; plant resistance ; deterrent activity ; quinolizidine alkaloids ; ammodendrine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Eleven varieties of Lupinus luteus were tested in choice and no-choice experiments for their resistance to feeding by the red-legged earth mite (Halotydeus destructor). Three were found to show resistance, and the alkaloid fraction from these varieties strongly deterred mites from feeding. The alkaloid components of the extracts, lupinine, a number of acyl derivatives of lupinine, and sparteine were tested for deterrent activity. Sparteine was the most potent, with significant activity at 0.001% concentration. Quantitation of the levels of nonpolar alkaloids in the cotyledons and leaves of the 11 varieties was by gas chromatography–mass spectrometry. An inverse correlation was found between the concentrations of these alkaloids and the damage caused by the mites; varieties with levels 〈100 μg/g (fresh wt) showed a high damage index. The involvement of sparteine and the bipiperidine alkaloid ammodendrine in the deterrence to mite feeding is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1005413606680
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Role of Isoflavonoids in Resistance of Subterranean Clover Trifoliates to the Redlegged Earth Mite Halotydeus destructor (1998)
    Springer
    Journal of chemical ecology 24 (1998), S. 2089-2100 
    Details
    ISSN: 1573-1561
    Keywords: Trifolium subterraneum ; trifoliates ; Halotydeus destructor ; free isoflavones ; bound isoflavones ; resistance ; deterrent activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Mature leaves of variety SE014 of Trifolium subterraneum are resistant to the redlegged earth mite (Halotydeus destructor). Compounds with feeding deterrent activity present in the leaves were isolated and identified by using a membrane bioassay technique. The free isoflavones, formononetin, genistein, and biochanin A, their corresponding 7-O-glucosides, and biochanin A 7-O-glucoside-6″-O-malonate and genistein 7-O-glucoside-6″-O-malonate, were active. In addition, the biosynthetic precursors of formononetin and genistein, 2,5,7-trihydroxy-4′-methoxyisoflavanol and 2,5,7,4′-tetrahydroxyisoflavanol, also were deterrent to the redlegged mites. The relative activity of these compounds was determined and some structure-activity correlations are noted. The constitutive defense mechanism that contributes to the resistance of subclover trifoliates to the mite contrasts with the induced chemical mechanism previously found for subterranean clover cotyledons.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1020789710706
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...