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  • Angiotensin II  (1)
  • Decision table  (1)
  • Springer  (2)
  • Blackwell Publishing Ltd
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    The international journal of advanced manufacturing technology 11 (1996), S. 353-365 
    ISSN: 1433-3015
    Keywords: Decision table ; Injection mould ; Mould cost estimation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract This paper presents a knowledge-based costing system (DTMOLD-1) for an electrical appliance manufacturer to assist mould cost estimation at the early design stage. The system is developed in the form of decision tables. Through the use of decision tables, numerous interrelated variables and technical data in the injection mould cost estimation process are organised and presented. When the features of a plastic part are input, the DTMOLD-1 will generate an estimated cost of the injection mould required to produce the part. The rationale behind the system as well as the methodologies used in the developmental process are discussed.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1423-0127
    Keywords: Rostral ventrolateral medulla ; Cardiovascular neurons ; Arterial blood pressure ; Angiotensin II ; Hypertension
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The interactive role of rostral ventrolateral medulla (RVL) cardiovascular neurons and brain angiotensin II (Ang II) in regulating the arterial blood pressure was examined by recording simultaneously the spontaneous activity of these spinal projecting neurons and the arterial blood pressure in the pentobarbital-anesthetized spontaneously hypertensive rat (SHR) and its normotensive control, the Wistar Kyoto rat (WKY). It was found that Ang II elicited dose-dependent excitatory responses in a subpopulation of RVL cardiovascular neurons, followed by a subsequent increase in blood pressure. These effects of Ang II were significantly greater in SHR than in WKY. The effects were attenuated or abolished by co-administration of Ang II antagonist, [Sar1, Ile8]-Ang II. Pre-administration of [Sar1, Ile8]-Ang II to RVL using bilateral microinjection attenuated the blood pressure effects of intracerebroventricularly administered Ang II by as much as 70%. These results indicated that spinal projecting RVL cardiovascular neurons are important in mediating the pressor action of Ang II. The enhanced sensitivity and responsiveness of RVL cardiovascular neurons to Ang II may be pertinent to the genesis of hypertension in adult SHR.
    Type of Medium: Electronic Resource
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