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  • Springer  (189)
  • Nature Publishing Group  (47)
  • Blackwell Publishing Ltd  (17)
  • 1
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    Non-invasive assessment of selective 5-HT 1B/1D -receptor agonist-induced peripheral vascular effects in humans: comparison of different techniques (2002)
    Springer
    Details
    Publication Date: 2002-08-01
    Print ISSN: 0031-6970
    Electronic ISSN: 1432-1041
    Topics: Chemistry and Pharmacology , Medicine
    Published by Springer
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    PAPER CURRENT
  • 2
    Electronic Resource
    Electronic Resource
    Deformation and metamorphism in the Bard area of the Sesia Lanzo Zone, Western Alps, during subduction and uplift (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of metamorphic geology 1 (1983), S. 0 
    Details
    ISSN: 1525-1314
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: The structure, microstructure and petrology of a small area close to the village of Bard in Val d'Aosta (Italy) has been studied in detail. The area lies across the contact between the Gneiss Minuti (GM) and the Eclogitic Micaschist (EMS) Complexes of the Lower element of the Sesia portion of the Sesia-Lanzo Zone (Western Alps). Both complexes have undergone high-pressure metamorphism, but the metamorphic assemblages indicate a sudden increase in pressure in going across the contact from the GM to the EMS. Therefore, we interpret the contact as a thrust dividing the lower element of the Sesia into two sub-elements. This interpretation is supported by structural evidence.The early Alpine (90-70 Ma) metamorphic history is best preserved in the EMS and is one of increasing pressure associated with thrusting. The maximum P/T recorded in the EMS is 〉1500 MPa (〉15kbar) and 550°C and in the GM is 〈 1500-1300 MPa (〈 15-13 kbar) and 500-550°C. We suggest that the rocks were probably in an active Benioff zone during this time.From then on the histories of the GM and EMS are the same. Deformation continued and the thrust and thrust slices were folded during decreasing pressure. We interpret the first postthrusting deformation in terms of uplift associated with continued shortening of the crust and underplating after the Benioff zone had become inactive and a new Benioff zone had developed further to the north-west.A still later deformation and the Lepontine metamorphism (38 Ma) are related to continued uplift. Much of this deformation is characterized by structures indicative of vertical shortening and lateral spreading as the mountains rose above the general level of the surface.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1525-1314.1983.tb00268.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Effect of sheep, deer and cattle dung on herbage production and soil nutrient content (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Grass and forage science 50 (1995), S. 0 
    Details
    ISSN: 1365-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: A field experiment compared the effects of sheep, deer and cattle dung on pasture growth and soil nutrient status. Sheep and deer dung pellets degraded rapidly within three to eight weeks, while it was 12 months before all visible cattle dung had gone from the soil surface. The cattle dung initially reduced herbage yield owing to smothering. However, after 40 days, herbage around the edges of the dung patch responded positively to the dung and more dry matter was produced in this patch than in the control patch during the first 12 months. There was no measurable herbage response to sheep dung, but deer dung significantly increased herbage production. While the rate of nutrient application per unit area was similar for sheep and deer dung, the latter was more evenly spread within the patch area. Consequently, a greater percentage of pasture plants in the patch received nutrient additions from the deer dung and a measurable response was recorded. Twelve months after dung application, soil nitrate, phosphate and organic C were higher in dung patches than in the control patches. In cattle dung patches, this response was accompanied by higher microbial biomass C levels, arylsulphatase and arylphosphatase activities. Some residual effect on organic C levels was still evident three years after cattle dung application.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2494.1995.tb02322.x
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  • 4
    Electronic Resource
    Electronic Resource
    National Rivers Authority Initiatives in the Development of Portable Monitoring Equipment (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Water and environment journal 6 (1992), S. 0 
    Details
    ISSN: 1747-6593
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: The use of automated equipment for monitoring water quality is a concept which has received considerable impetus since the Water Act 1989 was introduced. This paper reports on two initiatives by the National Rivers Authority to develop systems for use in their role as the guardians of the water environment. Portable systems have been developed for detection of episodic pollution events and instantaneous spot measurement of water quality.This paper outlines the principal activities of the development of the systems and their use.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1747-6593.1992.tb00739.x
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  • 5
    Electronic Resource
    Electronic Resource
    Restoring Coastal Wetlands: The Californian Experience (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Water and environment journal 6 (1992), S. 0 
    Details
    ISSN: 1747-6593
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Coastal wetlands are an important natural resource, providing habitat for fish and wildlife, particularly many rare or endangered species. These wetlands also serve important functions for the treatment of urban runoff and effluent discharges, the dissipation of wave energy, and shore protection. The US Fish and Wildlife Service estimates that approximately 45 000 km2 of US wetlands have been destroyed in the past two centuries.The importance of wetlands in the ecosystem has only begun to be understood during the past two decades, and there has been a major legislative effort to preserve, protect, and enhance existing coastal wetlands. The productivity of tidal wetlands is related directly to the hydrologic characteristics of the system, and some considerations for the hydrologic design for the enhancement or construction of tidal wetlands are outlined. Recent attention has focused on the use of dredged spoil materials from harbours or shippping channels to restore historic tidal wetlands. The hydrologic design criteria are illustrated through a series of case studies in California.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1747-6593.1992.tb00724.x
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  • 6
    Electronic Resource
    Electronic Resource
    A simple and inexpensive 4π light collector and two designs for a light meter for light attenuation studies (1980)
    Oxford, UK : Blackwell Publishing Ltd
    Freshwater biology 10 (1980), S. 0 
    Details
    ISSN: 1365-2427
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: SUMMARY. A simple 4π light collector is described suitable for light attenuation studies. It uses table tennis balls as light collectors and its spherical response is near to ideal. A circuit for a simple meter based on an operational amplifier is given as well as that for a direct-reading log-ratio meter. Both circuits are intended for use with selenium photocells. The cost of the materials for detector and simple meter is less than £30.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2427.1980.tb01223.x
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  • 7
    Electronic Resource
    Electronic Resource
    A Cloned Gene for Human Transferrin (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 646 (1991), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1991.tb18573.x
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  • 8
    Electronic Resource
    Electronic Resource
    A novel regulatory system required for pathogenicity of Xanthomonas campestris is mediated by a small diffusible signal molecule (1997)
    Oxford BSL : Blackwell Publishing Ltd
    Molecular microbiology 24 (1997), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Mutations in the seven clustered rpf genes cause downregulated synthesis of extracellular enzymes and reduced virulence of Xanthomonas campestris pathovar campestris (Xcc). The phenotype of mutants in one of the genes, rpfF, can be restored by a diffusible extracellular factor (DSF) produced by all Xcc strains tested, apart from rpfF and rpfB mutants. DSF accumulates in early stationary phase (when synthesis of enzymes is maximal), but levels decline subsequently. Addition of DSF to exponentially-growing wild-type bacteria does not cause precocious enzyme synthesis. rpfB and rpfF are expressed throughout growth, but the rate increases in early stationary phase. RpfB is predicted to be a long-chain fatty acyl CoA ligase, and RpfF shows some relatedness to enoyl CoA hydratases. The properties of DSF suggest that it may be a fatty-acid derivative, and certain lipid preparations possess DSF activity at higher concentrations. These include lipid extracts and acid-hydrolysed lipopolysaccharide and lipid A from Xcc, and purified dodecanoic and hydroxydodecanoic acid. DSF production is confined to certain xanthomonads. We propose a model for the DSF system, which represents a novel mechanism for regulating virulence factor synthesis in response to physiological or environmental changes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2958.1997.3721736.x
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  • 9
    Electronic Resource
    Electronic Resource
    A protein kinase C-like activity in Escherichia coli (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 5 (1991), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The protein kinase C (PKC) family comprises calcium- and phospholipid-dependent kinases whose activity is stimulated by diacylglycerol and tumour-promoting phorbol esters such as 12-tetradecanoyl phorbol-13-acetate (TPA). In the Gram-negative bacterium Escherichia coli, functional similarity to PKC was demonstrated in crude extracts by calcium and phospholipid-dependent, TPA-stimulated phosphorylation of a small number of endogenous substrates. Activity was reduced by sphingosine, a known inhibitor of eukaryotic PKC. Structural similarity to PKC was demonstrated in crude and partially purified bacterial extracts by cross-reactivity with several monoclonal antibodies. This revealed isozyme-specific homology between a protein(s) of relative molecular mass 80–85000 in E. coli and the α-and γ-isozymes, but probably not the β-isozyme, of eukaryotic PKC.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.1991.tb01857.x
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  • 10
    Electronic Resource
    Electronic Resource
    A novel strategy for the isolation of luxl homologues: evidence for the widespread distribution of a LuxR:Luxl superfamily in enteric bacteria (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 10 (1993), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The pheromone N-(3-oxohexanoyl)-L-homoserine lactone (OHHL) regulates expression of bioluminescence in the marine bacterium Vibrio fischeri, the production of carbapenem antibiotic in Erwinia carotovora and exoenzymes in both E. carotovora and Pseudomonas aeruginosa. A characteristic feature of this regulatory mechanism in V. fischeri is that it is cell density-dependent, reflecting the need to accumulate sufficient pheromone to trigger the induction of gene expression. Using a lux plasmid-based bioluminescent sensor for OHHL, pheromone production by E. carotovora, Enterobacter agglomerans, Hafnia alvei, Rahnella aquatilis and Serratia marcescens has been demonstrated and shown also to be cell density-dependent. Production of OHHL implies the presence in these bacteria of a gene equivalent to luxl. Chromosomal banks from all five enteric bacteria have yielded clones capable of eliciting OHHL production when expressed in Escherichia coli. The luxl homologue from both E. carotovora (carl) and E. agglomerans (eagl) were characterized at the DNA sequence level and the deduced protein sequences have only 25% identity with the V. fischeri Luxl. Despite this, carl, eagl and luxl are shown to be biologically equivalent. An insertion mutant of eagl demonstrates that this gene is essential for OHHL production in E. agglomerans.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.1993.tb00923.x
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