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    Electronic Resource
    Electronic Resource
    Multi-copy nuclear pseudogenes of mitochondrial DNA reveal recent acute genetic changes in the human genome (1995)
    Springer
    Current genetics 28 (1995), S. 410-414 
    Details
    ISSN: 1432-0983
    Keywords: Mitochondrial DNA ; Multi-copy ; Pseudogene ; Evolution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Four nuclear pseudogenes homologous to the 10031–10195-bp region of the human mitochondrial genome were detected by constant denaturant capillary electrophoresis. Among them, one pseudogene is present as at least five copies in each cell, in accordance with our previous observations of multi-copy mitochondrial DNA pseudogenes. The presence of multiple identical copies of pseudogenes suggests that the human genome underwent a series of genetic changes, including gene amplifications, very recently in evolutionary history, i.e., within the last 390000 years.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00310808
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