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  • Articles  (46)
  • Springer  (43)
  • American Society of Hematology  (2)
  • Periodicals Archive Online (PAO)  (1)
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  • Articles  (46)
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  • 1
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    Oxford : Periodicals Archive Online (PAO)
    Economic Inquiry. 23:1 (1985:Jan.) 115 
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  • 2
    ISSN: 1432-0827
    Keywords: Mineralization ; Bone culture ; Osteoblast ; Matrix vesicles ; Hormone response
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Cell populations derived from adult rat bone were grown in cell culture and characterized with respect to their morphology and response to hormones. The cells were isolated from adult rat calvaria by mechanical rather than enzymatic methods. Cultures were initiated in modified BGJb medium supplemented with fetal bovine serum. These cultures and several cloned populations derived from them retained the ability to mineralize in vitro even after extended serial passage. Cultures derived from an osteoblast-enriched population showed an initial positive cAMP response to PTH and PGE2, but not to TCT. The PTH and PGE2 responses diminished with serial passage. The PTH response was no longer measurable at passage 6, and the PGE2 response was not evident in passage 11. In one clone, the PGE2 response persisted through passage 16. Adult rat skin fibroblasts cultured similarly did not respond to PTH or TCT, but still had a significant PGE2 response through passage 21. The cultured cells formed multiple layers with localized areas of higher cell density. Mineral plaques with major diameters as great as 0.75 mm were evident in the areas of greater cell density. Less extensive mineral deposits were present throughout the culture. The mineral plaques consisted of apatite-like crystals deposited on an organic matrix. Matrix vesicles and mineralized spherules appeared to be associated with initial mineral deposition. The spherules apparently coalesced to form more complex mineralized structures. A limited amount of mineralization also was observed in rat skin fibroblast cultures.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Archives of environmental contamination and toxicology 21 (1991), S. 41-50 
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Dissipation of atrazine and its metabolite, desethylatrazine (DEA), was followed and a partial mass balance was calculated, following applications to a clay loam soil at the Animal Research Centre Farm, Ottawa, Canada between 1986 and 1990. The decline in residue in the upper 15 cm of the soil was calculated following the applications on 30 September 1986, 6 June 1987 and 10 May 1989. Residues that leached down the soil profile and appeared in tile drainage water, and the watertable were determined. Atrazine and DEA declined rapidly over the summer months with a half-life disappearance of 37 and 64 days for the parent and 42 and 68 days for the parent plus metabolite, respectively following the 1987 and 1989 applications. When the dissipation period was extended to cover the winter months (22 months) the half-life disappearance increased to 125 days for atrazine alone and 137 and 141 days for the parent plus metabolite. Applied in the fall, September 1986, the half-life disappearance was 198 days for atrazine and 327 days for atrazine plus DEA. An estimated minimum of 3.2 to 6.5% of the applied atrazine leached below 15 cm and was detected in the soil profile to a depth of 60 cm. Atrazine and DEA were found in all samples of the tile drainage water collected from the 1.0 m depth and in all groundwater samples beneath the field between a depth of 1.2 and 4.6 m, the maximum depth sampled. It was estimated that 1.9% of that applied was lost in the tile drainage water following a fall application and up to 0.2% from spring applications. A further 0.3 to 0.6% of that applied was present in the water table at any one time. Losses in surface runoff waters were minimal (〈0.01%) because of the flat topography and conservation tillage.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Archives of environmental contamination and toxicology 16 (1987), S. 9-22 
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Between the years 1979 and 1984, investigations were conducted into 311 events of suspected contaminations of wells with pesticides. This involved the analyses of water from 359 wells where the suspected contamination originated from (i) spills (ii) spray drift or (iii) surface runoff waters carrying pesticides into wells. Investigations covered 83 spill events involving 104 rural wells; tests revealed 79 of these became contaminated. The contaminations were caused by (i) spills of pesticide concentrates (ii) back-siphoning of spray solutions and/or (iii) spills from overfilling, emptying or rinsing spray equipment. The pesticides either entered directly into the wells or contaminated the area in the vicinity of the wells. In spite of cleanup attempts, difficulty was experienced in decontaminating most well waters and some had to be abandoned. The longest period of monitoring a contaminated well was 1, 117 days; during that time the decline in residue was slow. Investigations were made into 228 events involving 255 wells where spray drift and/or surface runoff waters with pesticides were observed as entering the well; however, only 55 were found to contain detectable residues. The highest proportion of these events was associated with surface runoff or spray drift from cornfields; of 86 wells involved only 26 contained measurable residues and all involved atrazine. Fifty-seven well investigations were associated with spraying right-of-ways and 16 waters were contaminated with 2,4-D and dichlorprop. The remaining 13 well contaminations were associated with various other land-use activities. It required 45 to 347 days to decontaminate these 55 wells.
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Archives of environmental contamination and toxicology 17 (1988), S. 741-754 
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Water samples collected at the river mouth of the Grand, Saugeen and Thames rivers between January 1981 and December 1985 were analyzed for 20 herbicides, 25 insecticides and 3 fungicides that had been used in the basins. Thirteen herbicides were identified in river water; these ranged from single events in one basin over the five years to those appearing in most water samples from all three basins. Atrazine was the most frequently found pesticide present at measurable levels in 375 of 440 samples (85%). The second most frequently found pesticide was 2,4-D which was identified in 78 of 447 water samples (17%). No fungicides were detected in river water and only single events of two organophosphorus insecticides occurred in 446 samples analyzed (diazinon and malathion). Organochlorine insecticides were identified from both present and past use patterns. Heptachlor expoxide appeared as a breakdown product from the use of chlordane. The order by pesticide group in decreasing loadings at the river mouth were triazine herbicides 〈 chloroacetanilide herbicides 〈 chlorophenoxy and chlorobenzoic acid herbicides 〈 organochlorine insecticides. The highest loadings at the river mouth were for atrazine, which ranged from 0.1 to 8.2 metric tonnes per basin representing between 0.2 and 2.1% of that applied in the basin. Loadings of alachlor, metolachlor, and cyanazine represented up to 0.5 metric tonnes at the Thames river mouth, but negligible amounts for the other basins. Loading of chlorophenoxy herbicides and insecticides were infinitely lower than the triazines and chloroacetanilide herbicides. Some organochlorines of industrial origin were sought however, other than in 1981 when polychlorobiphenyls (PCBs) were present at measurable level; none were detected between 1982 and 1985.
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Archives of environmental contamination and toxicology 12 (1983), S. 265-269 
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Apples were dipped in a captan solution and allowed to equilibrate for 60 to 120 hr. Apples were then washed, diced, peeled, and cooked in several combinations to determine how the initial residues were removed. Rinsing, thorough washing, wiping, and combinations of these procedures reduced residues of captan by 43 to 94%. Boiling the whole apple or cooking the peeled and diced apple removed and destroyed 70 to 98% of the residue. The combination of thorough washing and cooking gave almost 100% removal. Peeling the unwashed apple transferred 30% of the captan residue to the pulp. The half-life of captan in water at pH 8.5 was found to be less than one hr at 22°C and 13 hr at 5°C; at pH 5.5 the half-life was 13 hr at 22°C and 208 hr at 5°C.
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  • 7
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Water samples from 11 wells located in an area of intensive vegetable production on an organic soil were collected in 1981 and 1982, and analyzed for pesticide residues. Residues of diazinon, malathion, allidochlor, linuron, and prometryne were identified in four of the wells. Water samples from 91 wells were collected from farms on mineral soils across Southern Ontario during 1984 and analyzed for pesticide residues. Atrazine residues (0.1 to 74 μg/L) were present in 11 wells and trifluralin residues (41μg/L) contaminated one well. The highest residue of atrazine (74 μg/L) was present in one well along with contamination of three other herbicides and one insecticide. This was the result of a spill into the drilled well that gave residues of each component between 22 and 125μg/L. After 10 months of cleaning, this well was still contaminated.
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Archives of environmental contamination and toxicology 3 (1975), S. 205-218 
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Eggs (307) were collected in 1971 from twenty species of birds with a variety of feeding habits from the Niagara Peninsula. This area of Ontario is intensively developed for agriculture and heavy industry and has a large urban population. Representative species were obtained from both the terrestrial and aquatic food chains. Eggs were analyzed for organochlorine insecticides, polychlorinated biphenyls, and total mercury. Eggs from carnivorous species at the top of the aquatic food chain had the highest mean residues of ΣDDT (7.6 to 22.4 ppm), PCB (3.5 to 74.0 ppm) and total mercury (0.64 to 0.83 ppm). Eggs from some terrestrial carnivores (red-tailed hawk and great horned owl) also had relatively high residues (2.5 to 3.9 ppm of ΣDDT, 0.2 to 1.0 ppm of PCB, 0.06 to 0.09 ppm of mercury), however levels were much lower than those found in eggs from aquatic-feeding carnivores. Eggs from one red-shouldered hawk had residues comparable to the aquatic feeding carnivores. Eggs from herbivorous and insectivorous birds of both aquatic and terrestrial environments contained much lower residues. PCB residues were slightly lower in eggs among the terrestrial feeding species (0.05 to 2.0 ppm) than among the aquatic feeders (0.14 to 4.0 ppm) and tended to be lower in eggs from terrestrial species collected in rural than in city environs. Levels of ΣDDT were similar in both groups with eggs from terrestrial feeders containing mean residues between 0.15 and 2.64 ppm and those from aquatic feeders between 0.33 and 2.79 ppm.
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of environmental contamination and toxicology 21 (1979), S. 515-520 
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of environmental contamination and toxicology 22 (1979), S. 500-507 
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
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