Publication Date:
2015-06-13
Description:
Article Gene transfer is a powerful technique to investigate the mechanistic basis of tumorigenesis. Here Zuckermann et al . adapt CRISPR/Cas9 genome editing to target potential oncogenes somatically in vivo , establishing a fast and convenient system for validating novel genetic candidates. Nature Communications doi: 10.1038/ncomms8391 Authors: Marc Zuckermann, Volker Hovestadt, Christiane B. Knobbe-Thomsen, Marc Zapatka, Paul A. Northcott, Kathrin Schramm, Jelena Belic, David T. W. Jones, Barbara Tschida, Branden Moriarity, David Largaespada, Martine F. Roussel, Andrey Korshunov, Guido Reifenberger, Stefan M. Pfister, Peter Lichter, Daisuke Kawauchi, Jan Gronych
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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