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  • Oxford University Press  (27)
  • American Physical Society (APS)  (20)
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  • 1
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    Axially and radially quantized spin waves in thick permalloy nanodots (2015)
    American Physical Society (APS)
    Details
    Publication Date: 2015-08-04
    Description: Author(s): X. Zhou, D. Kumar, I. S. Maksymov, M. Kostylev, and A. O. Adeyeye We have investigated the spin wave modes in perpendicularly magnetized permalloy nanodots as a function of film thickness using field modulated perpendicular ferromagnetic resonance spectroscopy. We observed mode intensity inversion with an increase in dot thickness. In thicker dots, one ellusive an… [Phys. Rev. B 92, 054401] Published Mon Aug 03, 2015
    Keywords: Magnetism
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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  • 2
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    Nano-optical imaging of WSe_{2} waveguide modes revealing light-exciton interactions (2016)
    American Physical Society (APS)
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    Publication Date: 2016-08-02
    Description: Author(s): Z. Fei, M. E. Scott, D. J. Gosztola, J. J. Foley, IV, J. Yan, D. G. Mandrus, H. Wen, P. Zhou, D. W. Zhang, Y. Sun, J. R. Guest, S. K. Gray, W. Bao, G. P. Wiederrecht, and X. Xu The authors perform near-field nanoimaging of various waveguide modes inside thin flakes of WSe 2 by using state-of-the-art near-field scanning optical microscopy. This compound is a prototypical transition metal dichalcogenide with strongly bound excitons. The nanoimaging data provides direct evidence of strong coupling between waveguide photon modes and excitons. Such coupling generates hybrid polaritonic modes that are imaged for the first time as propagative modes in real space. This work uncovers in real space the physics of nanoscale light-matter interactions in van der Waals semiconductors and thus provides guidelines for future applications of this class of materials in nanophotonics and optoelectronics. [Phys. Rev. B 94, 081402(R)] Published Mon Aug 01, 2016
    Keywords: Surface physics, nanoscale physics, low-dimensional systems
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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  • 3
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    Epidemic Clones, Oceanic Gene Pools, and Eco-LD in the Free Living Marine Pathogen Vibrio parahaemolyticus (2015)
    Oxford University Press
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    Publication Date: 2015-05-30
    Description: We investigated global patterns of variation in 157 whole-genome sequences of Vibrio parahaemolyticus , a free-living and seafood associated marine bacterium. Pandemic clones, responsible for recent outbreaks of gastroenteritis in humans, have spread globally. However, there are oceanic gene pools, one located in the oceans surrounding Asia and another in the Mexican Gulf. Frequent recombination means that most isolates have acquired the genetic profile of their current location. We investigated the genetic structure in the Asian gene pool by calculating the effective population size in two different ways. Under standard neutral models, the two estimates should give similar answers but we found a 27-fold difference. We propose that this discrepancy is caused by the subdivision of the species into a hundred or more ecotypes which are maintained stably in the population. To investigate the genetic factors involved, we used 51 unrelated isolates to conduct a genome-wide scan for epistatically interacting loci. We found a single example of strong epistasis between distant genome regions. A majority of strains had a type VI secretion system associated with bacterial killing. The remaining strains had genes associated with biofilm formation and regulated by cyclic dimeric GMP signaling. All strains had one or other of the two systems and none of isolate had complete complements of both systems, although several strains had remnants. Further "top down" analysis of patterns of linkage disequilibrium within frequently recombining species will allow a detailed understanding of how selection acts to structure the pattern of variation within natural bacterial populations.
    Print ISSN: 0737-4038
    Electronic ISSN: 1537-1719
    Topics: Biology
    Published by Oxford University Press
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  • 4
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    Hall effect within the colossal magnetoresistive semimetallic state of MoTe_{2} (2016)
    American Physical Society (APS)
    Details
    Publication Date: 2016-09-02
    Description: Author(s): Qiong Zhou, D. Rhodes, Q. R. Zhang, S. Tang, R. Schönemann, and L. Balicas Here, we report a systematic study on the Hall effect of the semimetallic state of bulk MoTe 2 , which was recently claimed to be a candidate for a novel type of Weyl semimetallic state. The temperature ( T ) dependence of the carrier densities and of their mobilities, as estimated from a numerical anal… [Phys. Rev. B 94, 121101(R)] Published Thu Sep 01, 2016
    Keywords: Electronic structure and strongly correlated systems
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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  • 5
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    Broadening the versatility of lentiviral vectors as a tool in nucleic acid research via genetic code expansion (2015)
    Oxford University Press
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    Publication Date: 2015-06-24
    Description: With the aim of broadening the versatility of lentiviral vectors as a tool in nucleic acid research, we expanded the genetic code in the propagation of lentiviral vectors for site-specific incorporation of chemical moieties with unique properties. Through systematic exploration of the structure–function relationship of lentiviral VSVg envelope by site-specific mutagenesis and incorporation of residues displaying azide- and diazirine-moieties, the modifiable sites on the vector surface were identified, with most at the PH domain that neither affects the expression of envelope protein nor propagation or infectivity of the progeny virus. Furthermore, via the incorporation of such chemical moieties, a variety of fluorescence probes, ligands, PEG and other functional molecules are conjugated, orthogonally and stoichiometrically, to the lentiviral vector. Using this methodology, a facile platform is established that is useful for tracking virus movement, targeting gene delivery and detecting virus–host interactions. This study may provide a new direction for rational design of lentiviral vectors, with significant impact on both basic research and therapeutic applications.
    Keywords: Cell biology, DNA-Mediated Cell Transformation and Nucleic Acids Transfer
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
    Published by Oxford University Press
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  • 6
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    DUAL SPACES AND JOHN-NIRENBERG INEQUALITIES OF MARTINGALE HARDY-LORENTZ-KARAMATA SPACES (2015)
    Oxford University Press
    Details
    Publication Date: 2015-06-05
    Description: In this paper, the generalized BMO martingale spaces are introduced as the dual spaces of martingale Hardy–Lorentz–Karamata spaces $H_{p,q,b}^s$ , which completes the very recent result [ Quart. J. Math. 65 (2014), 985–1009] in the case $0\lt p\leq 1, 1\lt q\lt \infty$ . Moreover, by duality we obtain a new John–Nirenberg theorem when the stochastic basis is regular.
    Print ISSN: 0033-5606
    Electronic ISSN: 1464-3847
    Topics: Mathematics
    Published by Oxford University Press
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  • 7
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    TMPRSS6, but not TF, TFR2 or BMP2 variants are associated with increased risk of iron-deficiency anemia (2012)
    Oxford University Press
    Details
    Publication Date: 2012-04-12
    Description: A variety of conditions lead to anemia, which affects one-quarter of the world's population. Previous genome-wide association studies revealed a number of genetic polymorphisms significantly associated with plasma iron status. To evaluate the association of genetic variants in genes involved in iron delivery and hepcidin regulation pathways with the risk of iron-deficiency anemia (IDA), the following single nucleotide polymorphisms were genotyped in 2139 unrelated elderly Chinese women: rs3811647 ( TF ), rs7385804 ( TFR2 ), rs235756 ( BMP2 ), and rs855791(V736A) and rs4820268 ( TMPRSS6, encoding matriptase-2). We identified common variants in TMPRSS6 as being genetic risk factors for both iron deficiency (OR rs855791 = 1.55, P = 4.96 x 10 –8 ) and IDA (OR rs855791 = 1.78, P = 8.43 x 10 –9 ). TMPRSS6 polymorphisms were also associated with lower serum iron (SI) and hemoglobin levels, consistent with their associations to increased iron deficiency and anemia risk. Variants rs3811647 in TF and rs7385804 in TFR2 were associated with reduced SI, serum transferrin and transferrin saturation levels; however, these variants were not associated with iron deficiency or anemia risk. Our findings suggest that TF , TFR2 and TMPRSS6 polymorphisms are significantly associated with decreased iron status, but only variants in TMPRSS6 are genetic risk factors for iron deficiency and IDA.
    Print ISSN: 0964-6906
    Electronic ISSN: 1460-2083
    Topics: Biology , Medicine
    Published by Oxford University Press
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  • 8
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    Hexagonal phase stabilization and magnetic orders of multiferroic Lu_{1−x} Sc_{x} FeO_{3} (2016)
    American Physical Society (APS)
    Details
    Publication Date: 2016-02-24
    Description: Author(s): L. Lin, H. M. Zhang, M. F. Liu, Shoudong Shen, S. Zhou, D. Li, X. Wang, Z. B. Yan, Z. D. Zhang, Jun Zhao, Shuai Dong, and J.-M. Liu Hexagonal LuFe O 3 has drawn a lot of research attention due to its contentious room-temperature multiferroicity. Due to the instability of hexagonal phase in the bulk form, most experimental studies focused on LuFe O 3 thin films which can be stabilized by strain using proper substrates. Here we report… [Phys. Rev. B 93, 075146] Published Tue Feb 23, 2016
    Keywords: Electronic structure and strongly correlated systems
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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  • 9
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    Calorie Elasticities with Income Dynamics: Evidence from the Literature (2015)
    Oxford University Press
    Details
    Publication Date: 2015-11-06
    Description: This paper proposes a finite mixture model to identify the behavioral transition of calorie consumption with an assumption that nutrition consumption is a mixture of behaviors in two different stages: a poor stage and an affluent stage. Based on a meta-analysis of 387 calorie-income elasticities collected from 90 primary studies, it is found that the threshold income for calorie demand transition is $460 in 2012 prices. This implies that the transitional threshold for calorie consumption is $1.26/day, which is slightly lower than the World Bank's poverty line ($1.25/day in 2005 purchasing power parity prices) after deflation. This study provides a new empirical approach to evaluate the transition of calorie consumption and poverty line.
    Keywords: D12 - Consumer Economics: Empirical Analysis
    Print ISSN: 2040-5790
    Electronic ISSN: 2040-5804
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Economics
    Published by Oxford University Press
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  • 10
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    Shared Genetic Signals of Hypoxia Adaptation in Drosophila and in High-Altitude Human Populations (2016)
    Oxford University Press
    Details
    Publication Date: 2016-01-24
    Description: The ability to withstand low oxygen (hypoxia tolerance) is a polygenic and mechanistically conserved trait that has important implications for both human health and evolution. However, little is known about the diversity of genetic mechanisms involved in hypoxia adaptation in evolving populations. We used experimental evolution and whole-genome sequencing in Drosophila melanogaster to investigate the role of natural variation in adaptation to hypoxia. Using a generalized linear mixed model we identified significant allele frequency differences between three independently evolved hypoxia-tolerant populations and normoxic control populations for approximately 3,800 single nucleotide polymorphisms. Around 50% of these variants are clustered in 66 distinct genomic regions. These regions contain genes that are differentially expressed between hypoxia-tolerant and normoxic populations and several of the differentially expressed genes are associated with metabolic processes. Additional genes associated with respiratory and open tracheal system development also show evidence of directional selection. RNAi-mediated knockdown of several candidate genes’ expression significantly enhanced survival in severe hypoxia. Using genomewide single nucleotide polymorphism data from four high-altitude human populations—Sherpas, Tibetans, Ethiopians, and Andeans, we found that several human orthologs of the genes under selection in flies are also likely under positive selection in all four high-altitude human populations. Thus, our results indicate that selection for hypoxia tolerance can act on standing genetic variation in similar genes and pathways present in organisms diverged by hundreds of millions of years.
    Print ISSN: 0737-4038
    Electronic ISSN: 1537-1719
    Topics: Biology
    Published by Oxford University Press
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