Publication Date:
2017-04-11
Description:
Cytoglobin regulates blood pressure and vascular tone through nitric oxide metabolism in the vascular wall Nature Communications, Published online: 10 April 2017; doi:10.1038/ncomms14807 The gaseous signalling molecule nitric oxide regulates vascular tone. Here, the authors show that nitric oxide is degraded by the enzyme cytoglobin in the vascular wall, and that mice lacking cytoglobin have reduced blood pressure and are less sensitive to angiotensin-mediated hypertension.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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