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Profile of Eva Nogales [Profile] (2016)

Davis, T. H.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2016-08-24

Description: Capturing the structural intricacies of a biomolecule whose function depends on its flexibility is akin to finding microscopic needles in a moving haystack. Freezing samples at cryogenic temperatures allows biophysicist Eva Nogales the opportunity to observe these molecules at high resolution in a near-native environment. Using cryo-electron microscopy (cryo-EM), Nogales,...

Keywords: PNAS Profiles

Print ISSN: 0027-8424

Electronic ISSN: 1091-6490

Topics: Biology , Medicine , Natural Sciences in General

Published by National Academy of Sciences

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Profile of Stephen E. Plog [Profiles] (2011)

Davis, T. H.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2011-06-01

Description: Within the confines of remote Chaco Canyon, large Pueblo great houses stand sentry among smaller dwellings, the palatial behemoths unoccupied and the nature of their growth and decline 1,000 years ago in this region of the American Southwest still under debate. In his Inaugural Article, archaeologist Stephen Plog, elected to the National Academy of Sciences in 2007, uses evidence from burials within one of these great houses to assert that these societies were not as egalitarian as their more modern Pueblo counterparts are, but that they supported a social hierarchy (1). The dead can, and do, tell tales, yet with...

Keywords: PNAS Profiles

Print ISSN: 0027-8424

Electronic ISSN: 1091-6490

Topics: Biology , Medicine , Natural Sciences in General

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Profile of Pamela J. Fraker [Profiles] (2012)

Davis, T. H.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2012-10-17

Description: A busy factory with intricate connections to the bloodstream, bone marrow is one of the most extensive—and active—tissues in the body, churning out cellular precursors of the bloodstream, immune system, fat, and bone. For all its activity, the response of the bone marrow to conditions like obesity is often ignored....

Keywords: PNAS Profiles

Print ISSN: 0027-8424

Electronic ISSN: 1091-6490

Topics: Biology , Medicine , Natural Sciences in General

Published by National Academy of Sciences

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Profile of Alexander S. Raikhel [Profiles] (2011)

Davis, T. H.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2011-01-04

Description: Mosquitoes rely on blood for nutrition, putting them in position to transmit some of the world's deadliest diseases, like malaria and Dengue fever. Alexander S. Raikhel, elected to the National Academy of Sciences in 2009, believes that preventing the mosquito from carrying the pathogen in the first place is the key to vector control. Raikhel has been studying the connection between blood meals and egg production in Aedes aegypti in hopes of co-opting egg production signals to activate the mosquito's immune system against incoming pathogens. In his Inaugural Article, Raikhel, a distinguished professor at the University of California, Riverside continues...

Keywords: PNAS Profiles

Print ISSN: 0027-8424

Electronic ISSN: 1091-6490

Topics: Biology , Medicine , Natural Sciences in General

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Profile of Yigong Shi [Profiles] (2014)

Davis, T. H.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2014-11-19

Description: Growing up in rural China under the imposed hardships of the cultural revolution, Yigong Shi did not have the luxury of toys. Instead Shi, now the dean of the School of Life Sciences at Tsinghua University in Beijing, made elaborate models out of clay he collected from the fields. “I...

Keywords: PNAS Profiles

Print ISSN: 0027-8424

Electronic ISSN: 1091-6490

Topics: Biology , Medicine , Natural Sciences in General

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Profile of Daniel E. Gottschling [Profiles] (2014)

Davis, T. H.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2014-10-01

Description: Geneticist Daniel E. Gottschling is driven by discovery. From doctoral projects involving the identification of the first self-splicing RNAs and telomere-binding proteins to recent work at the forefront of the cellular aging field, the Fred Hutchinson Cancer Research Center researcher’s career has leap-frogged from one area to another in the...

Keywords: PNAS Profiles

Print ISSN: 0027-8424

Electronic ISSN: 1091-6490

Topics: Biology , Medicine , Natural Sciences in General

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Profile of Alexander D. Johnson [Profiles] (2014)

Davis, T. H.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2014-08-20

Description: Discussing the yeast Candida albicans, biochemist Alexander Johnson describes a resident of the human gut that can turn into a fatal pathogen in the immunocompromised. Johnson, a professor of microbiology and immunology at the University of California, San Francisco, appreciates the genetic intricacies of this eukaryote that changed his views...

Keywords: PNAS Profiles

Print ISSN: 0027-8424

Electronic ISSN: 1091-6490

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Profile of Christine Petit [Profiles] (2017)

Tinsley H. Davis

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2017-08-04

Description: Over the last 20 years, geneticist and neurobiologist Christine Petit has written the canticle of the cochlea from scratch, revealing the long-shrouded machinery of the auditory system molecule by molecule. Along the way, she has identified more than 20 genes responsible for hearing impairments, with each of these cochlear deficits...

Keywords: PNAS Profiles

Print ISSN: 0027-8424

Electronic ISSN: 1091-6490

Topics: Biology , Medicine , Natural Sciences in General

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Profile of Daniel H. Janzen [Profiles] (2017)

Tinsley H. Davis

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2017-09-27

Description: When Daniel Janzen gave his acceptance speech for the 1997 Kyoto Prize, he disappointed many people who had come to hear a preeminent biologist discuss iconic studies, from ant–acacia mutualism to seed predation (1, 2). “They expected a talk about science, but I’d switched to conservation,” explains Janzen, DiMaura Professor...

Keywords: PNAS Profiles

Print ISSN: 0027-8424

Electronic ISSN: 1091-6490

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Profile of Dinshaw J. Patel [Profiles] (2015)

Davis, T. H.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2015-08-26

Description: Small-noncoding RNA molecules are the dark matter of molecular biology. From small interfering (si) RNAs that silence invading pathogens to microRNAs that fine-tune gene expression, noncoding RNAs carry out a vast number of functions within the cell. “It was generally believed in the early days of molecular biology that RNA...

Keywords: PNAS Profiles

Print ISSN: 0027-8424

Electronic ISSN: 1091-6490

Topics: Biology , Medicine , Natural Sciences in General

Published by National Academy of Sciences

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