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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Lifetime data analysis 5 (1999), S. 305-305 
    ISSN: 1572-9249
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Lifetime data analysis 4 (1998), S. 229-251 
    ISSN: 1572-9249
    Keywords: Bivariate Wiener process ; degradation ; failure time ; first-passage time ; marker process ; prediction ; reliability ; statistical inference
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract Many models have been proposed that relate failure times and stochastic time-varying covariates. In some of these models, failure occurs when a particular observable marker crosses a threshold level. We are interested in the more difficult, and often more realistic, situation where failure is not related deterministically to an observable marker. In this case, joint models for marker evolution and failure tend to lead to complicated calculations for characteristics such as the marginal distribution of failure time or the joint distribution of failure time and marker value at failure. This paper presents a model based on a bivariate Wiener process in which one component represents the marker and the second, which is latent (unobservable), determines the failure time. In particular, failure occurs when the latent component crosses a threshold level. The model yields reasonably simple expressions for the characteristics mentioned above and is easy to fit to commonly occurring data that involve the marker value at the censoring time for surviving cases and the marker value and failure time for failing cases. Parametric and predictive inference are discussed, as well as model checking. An extension of the model permits the construction of a composite marker from several candidate markers that may be available. The methodology is demonstrated by a simulated example and a case application.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Aequationes mathematicae 4 (1970), S. 276-276 
    ISSN: 1420-8903
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 60 (1995), S. 391-403 
    ISSN: 1432-0649
    Keywords: 34.80 ; 42.55Gp ; 52.65
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A theoretical model that accounts for fundamental plasma processes leading to the formation and decay of XeCs+ ionic excimers in high-pressure electron-beam-excited Ar/Xe/Cs mixtures was developed. Numerical calculations based on the model were performed. For atmospheric gas mixtures, the model predicts an intrinsic efficiency (energy stored in upper state/energy deposited) of 18%. Model calculations also indicate that while XeCs+ was predominantly formed via the rare-gas ion (Xe+) channel over the entire e-beam duration, the rare-gas metastable (Xe*) channel assumes dominance in the afterglow period.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 55 (1992), S. 365-367 
    ISSN: 1432-0649
    Keywords: 42.55.Mv ; 42.55.Rz ; 42.60
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Fluorescence and lasing properties of coumarindoped silica samples prepared by sol-gel process were investigated. Superradiant emissions at peak power as high as 7MW were measured at around 535 nm when the silica samples were excited by a XeF laser. The energy of the superradiant pulse was 89 mJ, corresponding to a conversion efficiency of 36.6%.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 56 (1993), S. 385-390 
    ISSN: 1432-0649
    Keywords: 42.55.M ; 42.55.R ; 42.60
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Lasing and fluorescence properties of ten dyes covering the spectral range from 400 nm to 800 nm were studied in a silica matrix prepared by the sol-gel technique. The dye-doped sol-gel silica samples fluoresced strongly under laser excitation. Many of the samples were also induced to superradiate. In comparison to dyes in alcohol solvents, significant red-shifting was observed in the sol-gel silica fluorescence spectra. Plausible causes of the red-shift are discussed.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of environmental contamination and toxicology 25 (1980), S. 118-121 
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular evolution 11 (1978), S. 293-311 
    ISSN: 1432-1432
    Keywords: HCN ; Cyanide ; HCN oligomers ; 4,5-Dihydroxypyrimidine ; Orotic Acid ; 5-Hydroxyuracil ; Adenine ; 4-Aminoimidazole-5-carboxamide ; Prebiotic ; Primitive earth
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Dilute (0.1M) solutions of HCN condense to oligomers at pH 9.2. Hydrolysis of these oligomers yields 4,5-dihydroxypyrimidine, orotic acid, 5-hydroxyuracil, adenine, 4-aminoimidazole-5-carboxamide and amino acids. These results, together with the earlier data, demonstrate that the three main classes of nitrogen-containing biomolecules, purines, pyrimidines and amino acids may have originated from HCN on the primitive earth. The observation of orotic acid and 4-aminoimidazole-5-carboxamide suggests that the contemporary biosynthetic pathways for nucleotides may have evolved from the compounds released on hydrolysis of HCN oligomers.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular evolution 12 (1979), S. 365-367 
    ISSN: 1432-1432
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Origins of life and evolution of the biospheres 15 (1985), S. 77-88 
    ISSN: 1573-0875
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences
    Notes: Abstract The effect of adsorbed ions and pH on the adsorption of several purine and pyrimidine nucleotides on montmorillonite was studied. The cations used to prepare homoionic montmorillonite were Na+, Mn2+, Fe3+, Co2+, Ni2+, Cu2+, and Zn2+. The nucleotides studied were 5′-, 3′-, and 2′-AMP, and 5′-CMP in the pH range 2 through 12. The results show that preferential adsorption amongst nucleotides and similar molecules is dependent upon pH and the nature of the substituted metal cation in the clay. At neutral pH, it was observed that 5′-AMP was more strongly adsorbed than 2′-AMP, 3′-AMP, and 5′-CMP. Cu2+ and Zn2+ clays showed enhanced adsorption of 5′-AMP compared to the other cation clays studied in the pH range 4–8. Below pH 4, the adsorption is attributed to cation and anion exchange adsorption mechanisms; above pH 4, anion exchange may also occur, but the adsorption (when it occurs) likely depends on a complexation mechanism occurring between metal cation in the clay exchange site and the biomolecule. It is thus proposed that homoionic clays may have played a significant role in the concentration mechanism of biomonomers in the prebiotic environment, a prerequisite step necessary for the formation of biopolymers in the remaining steps leading to the origin of life.
    Type of Medium: Electronic Resource
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