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  • Articles  (59)
  • Springer  (59)
  • American Institute of Physics (AIP)
  • Process Engineering, Biotechnology, Nutrition Technology  (37)
  • Computer Science  (22)
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  • Articles  (59)
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  • 1
    Electronic Resource
    Electronic Resource
    Bernstein form is inclusion monotone (1995)
    Springer
    Computing 55 (1995), S. 43-53 
    Details
    ISSN: 1436-5057
    Keywords: Interval analysis ; range computation ; inclusion monotonicity ; Bernstein coefficients
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Zusammenfassung Bekanntlich ist der Wertebereich eines Polynomsf über einem Intervall durch den kleinsten und größten Koeffizienten vonf bezüglich der Bernstein Basis auf dem Intervall eingeschränkt. Dadurch wird eine IntervallerweiterungF vonf definiert, die sogenannte Bernstein Form. In dieser Arbeit zeigen wir, daß die Bernstein Form inklusionsmonoton ist, d. h. wenn.X⊇Y dannF(X)⊇F(Y).
    Notes: Abstract It is well known that the range of polynomialf over an interval is bounded by the smallest and the largest coefficient off with respect to the Bernstein basis over the interval. This defines an interval extensionF off, which is called Bernstein form. In this paper we show that the bernstein form is inclusion monotone, i.e.X⊇Y impliesF(X)⊇F(Y).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02238236
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  • 2
    Electronic Resource
    Electronic Resource
    A numerical taxonomy of Merovingian coins (1978)
    Springer
    Computers and the humanities 12 (1978), S. 201-214 
    Details
    ISSN: 1572-8412
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Media Resources and Communication Sciences, Journalism
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02392933
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  • 3
    Electronic Resource
    Electronic Resource
    Transformation of Penicillium chrysogenum by a vector containing a mitochondrial origin of replication (1987)
    Springer
    Applied microbiology and biotechnology 26 (1987), S. 237-241 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary In order to establish a transformation system for P. chrysogenum autonomously replicating vectors were constructed using mitochondrial DNA sequences from the fungus. A physical map of the mt DNA of a production strain was established using ten different restriction enzymes. Unexpectedly, the mt DNA of this strain proved to be significantly smaller than that of a second strain from a culture collection (27 kb versus 49 kb). Various fragments representing about 71% of the 27 kb mt DNA were cloned and, at first, preselected for replicating activity in an intermediate host (Saccharomyces cerevisiae). Two of these fragments also promoted autonomous replication in P. chrysogenum, which was confirmed by isolation of bulk DNA and transfer into E. coli. For selection of transformants in P. chrysogenum the prokaryotic kanamycin resistance gene was used which increased about twofold the resistance against G418.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00286316
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  • 4
    Electronic Resource
    Electronic Resource
    Life cycle, meiotic recombination and unilateral gene transfer in methanolotrophic yeasts of the genus Pichia (1987)
    Springer
    Applied microbiology and biotechnology 27 (1987), S. 265-271 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary In order to perform strain improvement of the methanol utilising yeasts Pichia pinus and Pichia lindneri their life cycles were elucidated. Both yeasts are monoecious and self-fertile. Karyogamy by autodiploidization is followed by meiosis leading to Mendelian segregation within the offspring. In Pichia pinus crosses via cell or protoplast fusion is feasible as proven by tetrad analysis. This is not the case in Pichia lindneri. The only possiblity to obtain recombinants in this yeast is brought about by a yet unknown mechanism, leading to a unilateral transfer of genetic material, found after cocultivation of mutants. This is revealed by the evaluation of F1 offspring from meiotic divisions after autodiploidisation. Although analysis of nuclear and mitochondrial DNA revealed rather gross differences not only between the species but also within different strains of Pichia pinus, only a limited exchange of genetic material is possible in interstrain crosses.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00252929
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  • 5
    Electronic Resource
    Electronic Resource
    Safe starting regions by fixed points and tightening (1994)
    Springer
    Computing 53 (1994), S. 323-335 
    Details
    ISSN: 1436-5057
    Keywords: Nonlinear equation systems ; interval arithmetic ; safe starting regions ; tightening
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Zusammenfassung In dieser Arbeit wird eine Methode zur Bestimmung von Startintervallen mit garantierter Konvergenz für ein gegebenes nichtlineares Gleichungssystem vorgestellt. Die Methode ist eine verbesserung der gebräuchlichen, auf dem Fixpunkt Theorem basierenden Methode. Die Verbesserung wird durch Einschließen der Komponenten des Gleichungssystems durch univariate Intervallpolynome, deren Lösungsmengen berechnet werden, erzielt. Diese Operation wird “Einengung” genannt. Erste experimentelle Untersuchungen zeigen, daß Einengung im allgemeinen die Anzahl der Intervallhalbierungen und somit die Rechenzeit reduziert. Die Reduktion scheint umso signifikanter, je höher die Anzahl der Variablen ist.
    Notes: Abstract In this paper, we present a method for finding safe starting regions for a given system of non-linear equations. The method is an improvement of the usual method which is based on the fixed point theorem. The improvement is obtained by enclosing the components of the equation system by univariante interval polynomials whose zero sets are found. This operation is called “tightening”. Preliminary experiments show that the tightening operation usually reduces the number of bisections, and thus the computing time. The reduction seems to become more dramatic when the number of variables increases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02307383
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  • 6
    Electronic Resource
    Electronic Resource
    The Appropriateness of Predicate Invention as Bias Shift Operation in ILP (1995)
    Springer
    Machine learning 20 (1995), S. 95-117 
    Details
    ISSN: 0885-6125
    Keywords: Inductive Logic Programming ; Bias Shift ; Predicate Invention
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract The task of predicate invention in Inductive Logic Programming is to extend the hypothesis language with new predicates if the vocabulary given initially is insufficient for the learning task. However, whether predicate invention really helps to make learning succeed in the extended language depends on the language bias currently employed. In this paper, we investigate for which commonly employed language biases predicate invention is an appropriate shift operation. We prove that for some restricted languages predicate invention does not help when the learning task fails and we characterize the languages for which predicate invention is useful. We investigate the decidability of the bias shift problem for these languages and discuss the capabilities of predicate invention as a bias shift operation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1022638219164
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  • 7
    Electronic Resource
    Electronic Resource
    Ethanol production by Zymomonas and Saccharomyces, advantages and disadvantages (1983)
    Springer
    Applied microbiology and biotechnology 18 (1983), S. 387-391 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary In order to evaluate the potential of Zymomonas mobilis and Saccharomyces cerevisiae for biotechnological ethanol production both microbes were grown aerobically and anaerobically at different glucose concentrations. The optimal values for ethanol production related to the theoretical values are 94% for Zymomonas and 88% for Saccharomyces, both under anaerobiosis. The corresponding figures for biomass are 2.5 g/l and 6.5 g/l and for total acid content 16 mM/l and 12 mM/l respectively: for other byproducts (such as aldehydes, ketones, esters) 330 mg/l and 280 mg/l respectively. For industrial fermentation Z.mobilis seems to be inferior to S.cerevisiae, because the advantage of higher ethanol and the lower biomass production of the bacterium is disadvantaged by the decrease in pH from 6.3 to 3.3 during yeast fermentation thus making sterilization of the medium unnecessary. The formation of acids and other byproducts may be neglected in practice, since in contrast to previous assumptions they are easy to separate during the rectification.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00504750
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  • 8
    Electronic Resource
    Electronic Resource
    Highly efficient expression of homologous and heterologous genes in Bacillus megaterium (1989)
    Springer
    Applied microbiology and biotechnology 30 (1989), S. 343-350 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary By developing an efficient transformation system it was possible to reintroduce two different glucose dehydrogenase genes of Bacillus megaterium into this host. These genes were previously cloned, sequenced and expressed in Escherichia coli. Since the expression of one of these genes (gdhA) turned out to be extremely high in B. megaterium, an expression system for genes from closely and distantly related organisms using the controlling region of the gdhA gene was developed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00296622
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  • 9
    Electronic Resource
    Electronic Resource
    G418 resistance in the yeast Saccharomyces cerevisiae: comparison of the neomycin resistance genes from Tn5 and Tn903 (1989)
    Springer
    Applied microbiology and biotechnology 30 (1989), S. 388-394 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary The neo genes of Tn5 and Tn903 (Tn601) coding for amigoglycoside phosphotransferase type II and type I, respectively, were joined to the yeast adc 1 promoter and trp1 terminator and introduced into yeast (Saccharomyces cerevisiae) cells. Transformants were obtained by direct selection for G418 resistance. Plasmids containing the Tn5 neo gene induced antibiotic resistance only at low frequency, whereas colonies transformed with the Tn903 neo gene could be selected at high frequency (300–400 transformants/μg plasmid DNA). The resistance threshold of transformed strains was increased to 30 mg G418/ml by both genes and high level expression of the bacterial genes in yeast could be shown using an in vitro phosphotransferase assay. The results indicate that this system can be used for high frequency transformation of wild-type strains and might in addition be used for the identification and isolation of promoter-active sequences.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00296629
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  • 10
    Electronic Resource
    Electronic Resource
    Flocculation in Saccharomyces cerevisiae and mitochondrial DNA structure (1988)
    Springer
    Applied microbiology and biotechnology 29 (1988), S. 48-54 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Mitochondrial mutants of indstrial yeast strains with different flocculation efficiencies were assayed for involvement of mitochondrial DNA (mtDNA) in flocculation. Most of the mutants exhibited a decreased flocculation rate in comparison to that of the wild strains. The mtDNA of a moderately flocculating wild strain was characterized by restriction enzyme analysis and by the localization of several mitochondrial genes. This molecular analysis of mitochondrial mutants revealed two areas of mtDNA involvement in flocculation, namely a region of the subunit 9 of the ATPase gene (oli 1) and a region of the subunit 3 of the cytochrome-c-oxidase gene (oxi 2).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00258350
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