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  • 1
    Publication Date: 2016-03-24
    Description: Rotary ATPases couple ATP synthesis or hydrolysis to proton translocation across a membrane. However, understanding proton translocation has been hampered by a lack of structural information for the membrane-embedded a subunit. The V/A-ATPase from the eubacterium Thermus thermophilus is similar in structure to the eukaryotic V-ATPase but has a simpler...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 2
    Publication Date: 2015-04-15
    Description: Food intake and body weight regulation depend on proper expression of the proopiomelanocortin gene (Pomc) in a group of neurons located in the mediobasal hypothalamus of all vertebrates. These neurons release POMC-encoded melanocortins, which are potent anorexigenic neuropeptides, and their absence from mice or humans leads to hyperphagia and severe...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 69 (1991), S. 7118-7125 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Conventional upper and lower bounds on the effective conductivity σe of two-phase composite media diverge from one another in the infinite-contrast limits (α=∞ or 0). We have derived a generally nontrivial upper bound on σe for suspensions of identical spheres when the spheres are superconducting, i.e., the upper bound does not necessarily become infinite in the limit α→∞. Similarly, a generally nontrivial lower bound on σe is derived for the aforementioned suspension when the spheres are perfect insulators, i.e., the lower bound does not necessarily vanish in the limit α→0. The bounds are computed for two models: simple cubic arrays and random arrays of spheres.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Annals of operations research 33 (1991), S. 481-499 
    ISSN: 1572-9338
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Economics
    Notes: Abstract Supposen points are given in the plane. Their coordinates form a 2n-vectorX. To study the question of finding the shortest Steiner networkS connecting these points, we allowX to vary over a configuration space. In particular, the Steiner ratio conjecture is well suited to this approach and short proofs of the casesn=4, 5 are discussed. The variational approach was used by us to solve other cases of the ratio conjecture (n=6, see [11] and for arbitraryn points lying on a circle). Recently, Du and Hwang have given a beautiful complete solution of the ratio conjecture, also using a configuration space approach but with convexity as the major idea. We have also solved Graham's problem to decide when the Steiner network is the same as the minimal spanning tree, for points on a circle and on any convex polygon, again using the variational method.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Commentarii mathematici Helvetici 73 (1998), S. 499-515 
    ISSN: 1420-8946
    Keywords: Key words. Graph manifold, $\pi_1$-injective surface, separable, simple loop conjecture, k-plane property.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract. A criterion is given for an immersed horizontal $\pi_1$ -injective surface in a graph manifold to be separable. Examples are constructed of such surfaces, which are not separable and do not satisfy the k-plane property, for any k. It is shown that the simple loop conjecture holds in graph manifolds and that any graph manifold with boundary has an immersed horizontal surface.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Zeitschrift für angewandte Mathematik und Physik 46 (1995), S. 739-751 
    ISSN: 1420-9039
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Notes: Abstract We study a few problems related to superconducting vortices. Our main concern is the stable equilibrium distribution of them. Our starting point is the asymptotic form of the Ginzburg Landau energy functional with a large Ginzburg Landau parameter. We consider in particular the interaction of the vortices with an applied magnetic field, and the effects of impurities on the vortex locations.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Algorithmica 7 (1992), S. 193-218 
    ISSN: 1432-0541
    Keywords: Graham's conjecture ; Steiner trees ; Spanning trees ; Variational approach ; Cocircular points
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract Suppose a configurationX consists ofn points lying on a circle of radiusr. If at most one of the edges joining neighboring points has length strictly greater thanr, then the Steiner treeS consists of all these edges with a longest edge removed. In order to showS is, in fact, just the minimal spanning treeT, a variational approach is used to show the Steiner ratio for this configuration is at least one and equals one only ifS andT coincide. The variational approach greatly reduces the number of possible Steiner trees that need to be considered.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Discrete & computational geometry 9 (1993), S. 323-333 
    ISSN: 1432-0444
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract SupposeX is a convex configuration with radius of maximum curvaturer and at most one of the edges joining neighboring points has length strictly greater thanr. We use the variational approach to show the Steiner treeS coincides with the minimal spanning tree and consists of all these edges with a longest edge removed. This generalizes Graham's problem for points on a circle, which we had solved. In addition we describe the minimal spanning tree for certain convex configurations.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Discrete & computational geometry 7 (1992), S. 77-86 
    ISSN: 1432-0444
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract A Steiner minimal treeS is a network of shortest possible length connecting a set ofn points in the plane. LetT be a shortest tree connecting then points but with vertices only at these points.T is called a minimal spanning tree. The Steiner ratio conjecture is that the length ofS divided by the length ofT is at least √3/2. In this paper we use a variational approach to show that if then points lie on a circle, then the Steiner ratio conjecture holds.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Biological cybernetics 70 (1994), S. 563-567 
    ISSN: 1432-0770
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Computer Science , Physics
    Notes: Abstract A model is proposed for the formation of singularities in the director field of orientation-selective cells in the visual cortex. The model consists of a two-layer associative neural net. The forward connections converge to a continuum of steady states. The degeneracy is removed by lateral interactions. It is shown that in many cases the director field contains critical points which are identified as the vortex locations.
    Type of Medium: Electronic Resource
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