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  • 1
    Electronic Resource
    Electronic Resource
    Equilibrium constant for the methyl tert-butyl ether liquid-phase synthesis using UNIFAC (1983)
    s.l. : American Chemical Society
    Industrial and engineering chemistry 22 (1983), S. 219-223 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/i100010a013
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  • 2
    Electronic Resource
    Electronic Resource
    Preparation and evaluation of [^9^9^mTc]DEPE as a cardiac perfusion agent
    Amsterdam : Elsevier
    The @International Journal Of Applied Radiation And Isotopes 35 (1984), S. 507-515 
    Details
    ISSN: 0020-708X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0020-708X(84)90172-8
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  • 3
    Electronic Resource
    Electronic Resource
    Factors influencing the service-like thermomechanical fatigue test cycle endurance of 1% CrMoV rotor steel (2003)
    PO Box 1354, 9600 Garsington Road, Oxford OX4 2XG, UK. : Blackwell Science Ltd
    Fatigue & fracture of engineering materials & structures 26 (2003), S. 0 
    Details
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Service-like thermomechanical fatigue tests have been performed in order to characterize the endurance of 1% CrMoV rotor steel under such transient thermal conditions. The key features of these tests are low strain rates (≤10−5 s−1) and longer hold periods. In all testpieces, ratcheting with progressive section reduction is observed in the central portion of the gauge length accompanied by local amplification of the strain range. The finite-element-based analysis of this phenomenon allows the measured endurances to be rationalized with those determined from isothermal tests. Post-test inspection has revealed the development of two concurrent damaging mechanisms in the testpieces: (i) fatigue at the surface and (ii) creep in the interior. Different methods of damage calculation for creep–fatigue interaction are applied and compared in their predictive capabilities.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1460-2695.2003.00689.x
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  • 4
    Electronic Resource
    Electronic Resource
    ^9^9^mTc complexes of α,α-disubstituted, α-hydroxy carboxylic acids
    Amsterdam : Elsevier
    International Journal of Radiation Applications & Instrumentation. Part 41 (1990), S. 221-227 
    Details
    ISSN: 0883-2889
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0883-2889(90)90113-U
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  • 5
    Electronic Resource
    Electronic Resource
    Sensitive GC-MS method for the determination of specific-activity of 16α[^1^8F]fluoro-estra- 1,3,5(10)-triene-3,17β-diol
    Amsterdam : Elsevier
    International Journal of Radiation Applications & Instrumentation. Part 43 (1992), S. 1299-1300 
    Details
    ISSN: 0883-2889
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0883-2889(92)90210-6
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  • 6
    Electronic Resource
    Electronic Resource
    Occupational risk to rare earths
    Amsterdam : Elsevier
    Inorganica Chimica Acta 94 (1984), S. 143-144 
    Details
    ISSN: 0020-1693
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0020-1693(00)94606-1
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  • 7
    Electronic Resource
    Electronic Resource
    Beta-blockade antagonism of tyramine-induced rise in blood pressure (1988)
    Springer
    European journal of clinical pharmacology 34 (1988), S. 263-266 
    Details
    ISSN: 1432-1041
    Keywords: tyramine ; propranolol ; pressure response ; blood pressure ; beta-adrenoceptor blockers ; healthy volunteers ; indenolol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The effect β-adrenoceptor blockade on the pressor response to tyramine has been investigated in 6 healthy volunteers, each submitted to an i.v. tyramine pressor test before and after 7 days of propranolol 40 mg b.d. or indenolol 60 mg o.d. Tyramine was given as i.v. boluses of 1–6 mg, alternating with saline, in a randomized, single blind fashion. Prior to treatment tyramine caused a temporary, dose-dependent increase in systolic and diastolic blood pressure, whilst the heart rate remained unaffected. Both propranolol and indenolol reduced the pressor response to tyramine, as shown by a significant increase in ED15, i.e. the dose of tyramine required to increase systolic blood pressure by 15%.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00540953
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  • 8
    Electronic Resource
    Electronic Resource
    How informed general practitioners manage mild hypertension: a survey of readers of drug bulletins in 7 countries (1996)
    Springer
    European journal of clinical pharmacology 49 (1996), S. 445-450 
    Details
    ISSN: 1432-1041
    Keywords: Key words Practioners ; hypertension; general practice ; disease management ; international differences
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Objective: To determine whether general practitioners (GP) who are readers of independent drug bulletins can be used as an international epidemiological observatory of the criteria adopted by “well informed” doctors in various countries in the management of mild hypertension. Design: Questionnaire study of GPs’ diagnostic criteria for mild hypertension, routine investigation and management of patients with this diagnosis. Participants: 206 GPs readers of independent drug bulletins in 7 countries, comprising 95 known systematic readers of a local bulletin and 111 randomly selected regular subscribers. Main outcome measures: Response rate to the questionaire. Diagnostic criteria, routine investigations, and treatment used for patients with mild hypertension. Results: The study required two months for planning and implementation. Four countries out of eleven had a response rate ≤ 50% and were excluded; the frequency of responses from other countries was 69%. The average diastolic blood pressure (DBP) considered diagnostic of mild hypertension range from 94 mm Hg (lower threshold) to 106 (upper threshold). A minority (17%) of GPs routinely request the minimum recommended laboratory tests to assess patients. GPs routinely advise non-drug measures before starting a drug. Most would not start drug treatment in patients without other risk factors and a DBP below 100 mmHg. The top first choice drugs were diuretics and β-adrenoceptor blockers. Half of the doctors were able to quote some published guide to the management of mild hypertension, and 18% cited a relevant trial. Attitudes in diagnosing and treating mild hypertension differed widely between GPs and countries. Conclusions: GP readers of drug bulletins can be used quickly and inexpensively to assess the extent to which recommended diagnostic and therapeutic practices are accepted by “well informed” doctors. The results suggest that attitudes in managing mild hypertension vary widely among GPs and countries and differ remarkably from the recommendations of published guidelines.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002280050048
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  • 9
    Electronic Resource
    Electronic Resource
    How informed general practitioners manage mild hypertension: a survey of readers of drug bulletins in 7 countries (1996)
    Springer
    European journal of clinical pharmacology 49 (1996), S. 445-450 
    Details
    ISSN: 1432-1041
    Keywords: Practioners ; hypertension ; general practice ; disease management ; international differences
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Objective: To determine whether general practitioners (GP) who are readers of independent drug bulletins can be used as an international epidemiological observatory of the criteria adopted by “well informed” doctors in various countries in the management of mild hypertension. Design: Questionnaire study of GPs' diagnostic criteria for mild hypertension, routine investigation and management of patients with this diagnosis. Participants: 206 GPs readers of independent drug bulletins in 7 countries, comprising 95 known systematic readers of a local bulletin and 111 randomly selected regular subscribers. Main outcome measures: Response rate to the questionaire. Diagnostic criteria, routine investigations, and treatment used for patients with mild hypertension. Results: The study required two months for planning and implementation. Four countries out of eleven had a response rate ≤50% and were excluded; the frequency of responses from other countries was 69%. The average diastolic blood pressure (DBP) considered diagnostic of mild hypertension range from 94 mm Hg (lower threshold) to 106 (upper threshold). A minority (17%) of GPs routinely request the minimum recommended laboratory tests to assess patients. GPs routinely advise non-drug measures before starting a drug. Most would not start drug treatment in patients without other risk factors and a DBP below 100 mmHg. The top first choice drugs were diuretics and β-adrenoceptor blockers. Half of the doctors were able to quote some published guide to the management of mild hypertension, and 18% cited a relevant trial. Attitudes in diagnosing and treating mild hypertension differed widely between GPs and countries. Conclusions: GP readers of drug bulletins can be used quickly and inexpensively to assess the extent to which recommended diagnostic and therapeutic practices are accepted by “well informed” doctors. The results suggest that attitudes in managing mild hypertension vary widely among GPs and countries and differ remarkably from the recommendations of published guidelines.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00195929
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  • 10
    Electronic Resource
    Electronic Resource
    Trace metals in human lung as determined by neutron activation analysis of bronchoalveolar lavage (1987)
    Springer
    Journal of radioanalytical and nuclear chemistry 110 (1987), S. 595-601 
    Details
    ISSN: 1588-2780
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract The possibility to use the bronchoalveolar lavage (BAL) in combination with analytical methods for trace metal analysis such as neutron activation analysis (NAA), inductively coupled plasma (ICP) and electrothermal atomic absorption spectroscopy (ETASS) for the determination of trace elements in the lung of living subjects has been investigated. In particular more than 30 elements have been determined: (1) in physiological solutions used for bronchopulmonary lavage (blank values) (2) in BALs of volunteer patients (unexposed subjects) (3) in BALs of occupational workers affected by pulmonary fibrosis as diagnosed by clinical methods (exposed subjects). Although the number of cases with metal exposure studied by NAA-BAL method is too limited to draw definitive conclusions the results suggest that the procedure can provide interesting qualitative information on metals which would be actually retained in the lung tissue. However, although the method may become of importance when integrated with clinical examinations further investigations are necessary to establish qualitative relations between trace metal levels determined in the BAL and the total elemental content of the lung tissue.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02035548
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