Publication Date:
2015-09-14
Description:
Three novel curcuminoids, curcumaromins A–C ( 1 – 3 , resp.), along with a known compound, longiferone B ( 4 ) were isolated from Curcuma aromatica Salisb . The structures of the new compounds were elucidated as (1 E ,4 Z ,6 E )-5-hydroxy-7-{4-hydroxy-3-[(1 R* ,6 R* )-3-methyl-6-(propan-2-yl)cyclohex-2-en-1-yl)phenyl}-1-(4-hydroxyphenyl)hepta-1,4,6-trien-3-one ( 1 ), 2,3-dihydro-2-(4-hydroxyphenyl)-6-[( E )-2-(4-hydroxyphenyl)ethenyl]-5-[(1 R* ,6 R* )-3-methyl-6-(propan-2-yl)cyclohex-2-en-1-yl]-4 H -pyran-4-one ( 2 ), and (1 E ,6 E )-1,7-bis(4-hydroxyphenyl)-4-[(1 R* ,6 R* )-3-methyl-6-(propan-2-yl)cyclohex-2-en-1-yl]hepta-1,6-diene-3,5-dione ( 3 ) on the basis of spectroscopic analysis. Curcumaromins A–C ( 1 – 3 ) represented the first examples of menthane monoterpene-coupled curcuminoids. The known compound, longiferone B ( 4 ), was the first daucane sesquiterpene isolated from the genus Curcuma.
Print ISSN:
0018-019X
Electronic ISSN:
1522-2675
Topics:
Chemistry and Pharmacology
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