Publication Date:
2015-01-22
Description:
Article Animals react to threats by increasing their heart rate. Wu et al . show that mitochondrial calcium uptake via a highly selective ion channel, the mitochondrial calcium uniporter, stimulates metabolism in cardiac pacemaker cells and is essential for physiological pulse acceleration but not resting heart rate. Nature Communications doi: 10.1038/ncomms7081 Authors: Yuejin Wu, Tyler P. Rasmussen, Olha M Koval, Mei-ling A. Joiner, Duane D. Hall, Biyi Chen, Elizabeth D. Luczak, Qiongling Wang, Adam G. Rokita, Xander H.T. Wehrens, Long-Sheng Song, Mark E. Anderson
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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