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  • Glycoprotein IIb/IIIa  (2)
  • ADP receptor  (1)
  • Springer  (2)
  • American Institute of Physics
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  • Springer  (2)
  • American Institute of Physics
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  • 1
    Electronic Resource
    Electronic Resource
    Design of antithrombotic agents: An introduction (1994)
    Springer
    Perspectives in drug discovery and design 1 (1994), S. 419-422 
    Details
    ISSN: 1573-9023
    Keywords: Hemostasis ; Factor Xa ; Thrombin ; Antithrombin III ; Protein C ; Protein S ; Thrombomodulin ; ADP receptor ; Thrombin receptor ; Fibrinogen receptor ; Glycoprotein IIb/IIIa
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary A brief overview of the control of hemostasis is presented that relates physiologically important functions and interactions of the proteins discussed in this volume, i.e.: factor Xa, thrombin, antithrombin III, protein C, protein S, thrombomodulin, ADP receptor, thrombin receptor and fibrinogen receptor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02171856
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The integrin αIIbβ3 as an antithrombotic target (1994)
    Springer
    Perspectives in drug discovery and design 1 (1994), S. 537-548 
    Details
    ISSN: 1573-9023
    Keywords: Glycoprotein IIb/IIIa ; Fibrinogen receptor ; Integrin ; Antithrombotic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary The objective of this paper is to review briefly the normal physiology of platelet activation which leads to aggregation, to summarize the evidence for the critical role of platelet activation and aggregation in thrombosis, to highlight the key role of the membrane-protein complex glycoprotein IIb/IIIa in this process, and to provide examples of how small molecules can inhibit the aggregatory function of this complex.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02171865
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    Paper (German National Licenses)
    Fulltext
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