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  • Carbon monoxide  (6)
  • twins  (5)
  • Springer  (11)
  • American Institute of Physics
  • Nature Publishing Group
  • Springer Nature
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  • Springer  (11)
  • American Institute of Physics
  • Nature Publishing Group
  • Springer Nature
  • Wiley-Blackwell  (1)
Years
  • 1
    Electronic Resource
    Electronic Resource
    Thermophilic Bacilli growing with carbon monoxide (1984)
    Springer
    Archives of microbiology 139 (1984), S. 402-408 
    Details
    ISSN: 1432-072X
    Keywords: Carboxydotrophic bacteria ; Bacillus schlegelii ; Species description ; Autotrophic growth ; Thermophilic bacteria ; Carbon monoxide ; Carbon monoxide oxidase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Four strains of obligately thermophilic Bacilli capable of growing with carbon monoxide as a sole carbon and energy source were isolated from settling ponds of a sugar factory. Most of them could be identified as strains of Bacillus schlegelii on the basis of cell wall composition, DNA homology menaquinone and DNA base content. Growth with CO was very fast (t d =3 h) and was optimal at 65°C. No growth occurred below 50°C. As with the mesophilic carboxydotrophs, hydrogen plus carbon dioxide could also serve as autotrophic substrates. Growth of the isolates with CO depended on the presence of molybdenum in the growth medium. This suggested CO oxidase in the newly isolated Bacilli being a molybdenum hydroxylase similar to the enzymes from the mesophilic carboxydotrophs. Some data characterizing the CO-oxidizing activity in extracts of the thermophilic isolates are also provided.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00408387
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  • 2
    Electronic Resource
    Electronic Resource
    Reisolation of the carbon monoxide utilizing hydrogen bacterium Pseudomonas carboxydovorans (Kistner) comb. nov. (1978)
    Springer
    Archives of microbiology 118 (1978), S. 35-43 
    Details
    ISSN: 1432-072X
    Keywords: Autotrophic growth ; Hydrogen ; Carbon monoxide ; Gram-negative hydrogen bacteria ; Pseudomonas carboxydovorans ; Facultative autotrophs ; CO oxidation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract From enrichment cultures four carbon monoxide utilizing bacteria were isolated; strain OM5 isolated from waste water was studied in detail. The cells are Gram-negative, slightly curved rods, motile by a single subpolarly inserted flagellum. The colonies are smooth, translucent and not slimy. The cells are able to grow autotrophically in mineral medium under an atmosphere of 40% CO, 5% O2 and 55% N2 at a doubling time of 20h (30°C) or of 85% H2, 5% O2 and 10% CO2 at a doubling time of 7h. Heterotrophic growth occurrd on organic acids such as acetate (t d =8h), pyruvate (t d =8h), lactate, crotonate, malate, succinate (t d =8h), formate (t d =35h) and glyoxylate as substrates. The enzyme system for carbon monoxide utilization is formed only during growth on CO; hydrogenase is present in cells grown on CO or on H2+CO2 as well as grown on pyruvate. The rate of oxygen reduction by intact CO-grown cells is 3.7-fold higher in the presence of hydrogen than in the presence of carbon monoxide. During growth the stoichiometry of gas uptake was 6.1 CO+2.8 O2+H2O → 〈CH2O〉+5.1 CO2. For the new isolate the name Pseudomonas carboxydovorans (Kistner) comb. nov. has been proposed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00406071
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  • 3
    Electronic Resource
    Electronic Resource
    CO2 is the first species formed upon CO oxidation by CO dehydrogenase from Pseudomonas carboxydovorans (1986)
    Springer
    Archives of microbiology 145 (1986), S. 358-360 
    Details
    ISSN: 1432-072X
    Keywords: Carbon monoxide ; Carbon dioxide ; CO dehydrogenase ; Carbonic anhydrase ; Pseudomonas carboxydovorans
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The active species of “CO2”, i.e. CO2 or HCO 3 - , formed in the CO dehydrogenase reaction was determined using the pure enzyme from the carboxydotrophic bacterium Pseudomonas carboxydovorans. Employing an assay system similar to that used to test for carbonic anhydrase, data were obtained which are quite compatible with those expected if CO2 is the first species formed. In addition, carbonic anhydrase activity was not detected in P. carboxydovorans.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00470871
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  • 4
    Electronic Resource
    Electronic Resource
    The cytochrome composition of carboxydotrophic bacteria (1983)
    Springer
    Archives of microbiology 135 (1983), S. 293-298 
    Details
    ISSN: 1432-072X
    Keywords: Carbon monoxide ; Carboxydotrophic bacteria ; Cytochromes ; Electron transport ; CO insensitivity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Spectroscopy at room and liquid nitrogen temperatures with extracts of the carbon monoxide-oxidizing bacteria Pseudomonas carboxydovorans, P. carboxydohydrogena, P. carboxydoflava, P. compransoris, Alcaligenes carboxydus, and Arthrobacter 11/x revealed the presence of normal electron transport systems, containing b-, c-, and a-type cytochromes at concentrations that compare to those of other aerobic bacteria. CO did not induce the formation of special CO-insensitive terminal oxidases. The gross composition of the respiratory chains was not affected by the type of growth substrate, and cytochrome d(=a2) was not detected. However, certain b-type cytochromes were only found when CO or H2 + CO2 served as growth substrates. All strains contained at least two different b-type cytochromes. Cytochrome b563 formed a weak CO-complex and was identified as a novel cytochrome o. It functions as CO-insensitive, alternative terminal oxidase in carboxydotrophic bacteria. A soluble CO-binding cytochrome c was present in P. carboxydovorans, P. carboxydohydrogena, and P. carboxydoflava. A CO-binding protoheme compound could be identified as catalase in P. compransoris, P. carboxydovorans, P. carboxydohydrogena, A. carboxydus, and Arthrobacter 11/x. The data are consistent with the presence of branched respiratory chains in the carboxydotrophs examined, and suggest the functioning of both, cytochrome a and the novel cytochrome o as terminal oxidases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00413484
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  • 5
    Electronic Resource
    Electronic Resource
    Plasmids in carboxydotrophic bacteria: physical and restriction analysis (1988)
    Springer
    Archives of microbiology 149 (1988), S. 540-546 
    Details
    ISSN: 1432-072X
    Keywords: Carbon monoxide ; Autotrophic bacteria ; Carboxydotrophic bacteria ; Plasmids ; Restriction analysis ; Mutants ; Deletion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Twenty species and strains of aerobic CO-oxidizing bacteria were screened for the occurrence of plasmids. Six of them harbored plasmids between 45 and 558kb. Megaplasmids of 428 and 558 kb were resolved in Alcaligenes carboxydus. Restriction digest patterns of plasmids from different carboxydotrophic bacteria were dissimilar. However, the patterns obtained with the plasmids from the strains OM5, OM4 and OM2 of Pseudomonas carboxydovorans were very much the same. The nine cured mutants of P. carboxydovorans OM5, as well as the deletion mutant OM5-29, could not grow chemolithotrophically with CO or H2 plus CO2, as they were devoid of CO dehydrogenase, hydrogenase and ribulose bisphosphate carboxylase. The deletion mutant OM5-24 retained the ability to grow with CO. It could not grow with H2 plus CO2 and was devoid of H2ase. The data suggest the residence of structural and/or regulatory genes of CODH, H2ase and RuBPCx on plasmid pHCG3 of P. carboxydovorans.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00446758
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  • 6
    Electronic Resource
    Electronic Resource
    The structural genes encoding CO dehydrogenase subunits (cox L, M and S) in Pseudomonas carboxydovorans OM5 reside on plasmid pHCG3 and are, with the exception of Streptomyces thermoautotrophicus, conserved in carboxydotrophic bacteria (1992)
    Springer
    Archives of microbiology 157 (1992), S. 301-304 
    Details
    ISSN: 1432-072X
    Keywords: Carbon monoxide ; CO ; Carboxydotrophic bacteria ; Plasmids ; CO Dehydrogenase ; Deoxyoligonucleotides ; Cox ; Pseudomonas carboxydovorans ; Pseudomonas carboxydohydrogena ; Pseudomonas carboxydoflava ; Streptomyces thermoautotrophicus ; Pseudomonas thermocarboxydovorans ; Bacillus schlegelii ; Alcaligenes carboxydus ; Arthrobacter ; Azomonas
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Employing deoxyoligonucleotide probes and Southern hybridizations, we have examined in carboxydotrophic bacteria the localization on the genome of genes encoding the large, medium and small subunits of CO dehydrogenase (coxL, M and S, respectively). In Pseudomonas carboxydovorans OM5 coxL, M and S were identified on the plasmid pHCG3; they were absent on the chromosome. This was evident from positive hybridizations with plasmid DNA of the wild-type strain OM5 and the absence of hybridizations with chromosomal DNA from the plasmid cured mutant strain OM5–12. The genes coxL, M and S were found on plasmids in all other plasmid-containing carboxydotrophic bacteria e.g. Alcaligenes carboxydus, Azomonas B1, Pseudomonas carboxydoflava, Pseudomonas carboxydovorans OM2 and OM4. Cox L, M and S could be identified on the chromosome of the plasmid-free bacteria Arthrobacter 11/x, Bacillus schlegelii, Pseudomonas carboxydohydrogena, and Pseudomonas carboxydovorans OM3. These results essentially confirm and extend former reports that cox genes are rather conserved among carboxydotrophic bacteria of distinct taxonomic position. However, Streptomyces thermoautotrophicus is an noteworthy exception since none of the three cox genes could be detected. This refers to a new type of CO dehydrogenase and is in accord with results indicating that the S. thermoautotrophicus CO dehydrogenase has an unusual electron acceptor specificity and some other properties setting it apart from the ‘classical’ CO dehydrogenases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00245166
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  • 7
    Electronic Resource
    Electronic Resource
    Resolving causes of developmental continuity or “tracking.” I. Longitudinal twin studies during growth (1988)
    Springer
    Behavior genetics 18 (1988), S. 133-151 
    Details
    ISSN: 1573-3297
    Keywords: genes ; environment ; development ; growth ; twins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract Models of developmental continuity and change in quantitative phenotypes may be tested using longitudinal data from twins. We illustrate a procedure for establishing the power and required sample sizes for detecting developmental transmission against an alternative common-factor hypothesis. We explore the general effects of different heritabilities, different fidelities of environmental and genetic developmental transmission, and varying numbers of occasions of measurement. In addition, a constraint of wide application is postulated for the action of the environment; either environmental effects are transmitted (learned) and occasion specific or they exert a constant influence which is not transmitted (learned). While the situations we examine are necessarily restricted here, our explorations of power show that, providing that we measure on at least four occasions, it is easy to detect developmental transmission with workable sample sizes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01067836
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  • 8
    Electronic Resource
    Electronic Resource
    Analyzing twin resemblance in multisymptom data: Genetic applications of a latent class model for symptoms of conduct disorder in juvenile boys (1993)
    Springer
    Behavior genetics 23 (1993), S. 5-19 
    Details
    ISSN: 1573-3297
    Keywords: Adolescence ; age ; categorical data ; conduct disorder ; development ; etiological heterogeneity ; genotype × environment interaction ; latent class models ; major gene ; segregation analysis ; twins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract A model based on the latent class model is developed for the effects of genes and environment on multivariate categorical data in twins. The model captures many essential features of dimensional and categorical conceptions of complex behavioral phenotypes and can include, as special cases, a variety of major locus models including those that allow for etiological heterogeneity, differential sensitivity of latent classes to measured covariates, and genotype × environment interaction (G×E). Many features of the model are illustrated by an application to ratings on eight items relating to conduct disorder selected from the Rutter Parent Questionnaire (RPQ). Mothers rated their 8-to 16-year-old male twin offspring [174 monozygotic (MZ) and 164 dizygotic (DZ) pairs]. The impact of age on the frequency of reported symptoms was relatively slight. Preliminary latent class analysis suggests that four classes are required to explain the reported behavioral profiles of the individual twins. A more detailed analysis of the pairwise response profiles reveals a significant association between twins for membership of latent classes and that the association is greater in MZ than DZ twins, suggesting that genetic factors played a significant role in class membership. Further analysis shows that the frequencies of MZ pairs discordant for membership of some latent classes are close to zero, while others are definitely not zero. One possible explanation of this finding is that the items reflect underlying etiological heterogeneity, with some response profiles reflecting genetic categories and others revealing a latent environmental risk factor. We explore two “four-class” models for etiological heterogeneity which make different assumptions about the way in which genes and environment interact to produce complex disease phenotypes. The first model allows for genetic heterogeneity that is expressed only in individuals exposed to a high-risk (“predisposing”) environment. The second model allows the environment to differentiate two forms of the disorder in individuals of high genetic risk. The first model fits better than the second, but neither fits as well as the general model for four latent classes associated in twins. The results suggest that a single-locus/two-allele model cannot fit the data on these eight items even when we allow for etiological heterogeneity. The pattern of endorsement probabilities associated with each of the four classes precludes a simple “unidimensional” model for the latent process underlying variation in symptom profile in this population. The extension of the approach to larger pedigrees and to linkage analysis is briefly considered.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01067550
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  • 9
    Electronic Resource
    Electronic Resource
    Genetic Effects on ADHD Symptomatology in 7- to 13-Year-Old Twins: Results from a Telephone Survey (1998)
    Springer
    Behavior genetics 28 (1998), S. 83-99 
    Details
    ISSN: 1573-3297
    Keywords: Attention-deficit hyperactivity disorder ; genetics ; twins ; oppositional-defiant disorder ; conduct disorder ; contrast effects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract The magnitude of genetic and environmental factors and the influence of contrast effects on attention-deficit hyperactivity disorder (ADHD) symptomatology were examined on a sample of 900 twin pairs, aged 7–13, participating in the Virginia Twin Study of Adolescent Behavioral Development (VTSABD). In addition, the genetic and environmental correlations between ADHD and oppositional-defiant disorder/conduct disorder (ODD/CD) symptomatology were estimated. A series of structural models was applied to maternal ratings from a telephone survey, designed to screen for the three dimensions of ADHD symptomatology (hyperactivity, impulsivity, and inattention) and ODD/CD symptomatology. Model-fitting results suggested that ADHD symptomatology is highly heritable and influenced mostly by additive genetic, specific environmental, and contrast effects. However, this analysis could not exclude with statistical significance additional effects from dominance. The results of the best-fitting bivariate model suggested that the genetic correlation between the two traits is 50% and replicated previous findings of a common genetic factor influencing the comorbidity of ADHD and ODD/CD symptomatologies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1021686906396
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  • 10
    Electronic Resource
    Electronic Resource
    A model for comparative ratings in studies of within-family differences (1991)
    Springer
    Behavior genetics 21 (1991), S. 531-536 
    Details
    ISSN: 1573-3297
    Keywords: twins ; siblings ; comparative judgments ; signal detection ; heritability ; Sibling Inventory of Differential Experience (SIDE)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract Comparative ratings between pairs of siblings or other relatives are commonly used to refine measures of intrafamily variation. A simple model, based on signal detection theory, is proposed which shows how comparative ratings can be used to estimate within-pair variances of true scores, which can, in turn, be modeled with any of the conventional approaches to partitioning genetic and environmental variance within families.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01066679
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