Publication Date:
2016-09-29
Description:
SEDS proteins are a widespread family of bacterial cell wall polymerases Nature 537, 7622 (2016). doi:10.1038/nature19331 Authors: Alexander J. Meeske, Eammon P. Riley, William P. Robins, Tsuyoshi Uehara, John J. Mekalanos, Daniel Kahne, Suzanne Walker, Andrew C. Kruse, Thomas G. Bernhardt & David Z. Rudner Elongation of rod-shaped bacteria is mediated by a dynamic peptidoglycan-synthetizing machinery called the Rod complex. Here we report that, in Bacillus subtilis, this complex is functional in the absence of all known peptidoglycan polymerases. Cells lacking these enzymes survive by inducing an envelope stress
Print ISSN:
0028-0836
Electronic ISSN:
1476-4687
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
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