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  • Candida albicans  (2)
  • Springer  (2)
  • American Institute of Physics
  • American Physical Society
  • Hindawi
  • National Academy of Sciences
  • PANGAEA
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Keywords
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  • Springer  (2)
  • American Institute of Physics
  • American Physical Society
  • Hindawi
  • National Academy of Sciences
    • +
Years
  • 1
    Electronic Resource
    Electronic Resource
    A novel antifungal from an Actinomadurae with preferential activity against the mycelial phase ofCandida albicans (1991)
    Springer
    Journal of industrial microbiology and biotechnology 8 (1991), S. 65-68 
    Details
    ISSN: 1476-5535
    Keywords: Antifungal ; Sch 40873 ; Candida albicans ; Mycelial
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Sch 40873, a novel antifungal compound isolated from the fermentation broth of anActinomadura spp. was discovered in an assay designed to detect compounds with preferential activity against the invasive mycelial form ofCandida albicans. The geometric mean MIC of Sch 40873 against sevenCandida spp. in Sabouraud dextrose broth (yeast phase) was ≥58 μg/ml and in Eagles minimum essential medium (mycelial phase) was 〈0.03 μg/ml. Sch 40873 demonstrated slight in vivo topical activity in a hamster vaginal model.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01575593
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Yeasts and fluconazole susceptibility in the Philippines (1999)
    Springer
    Mycopathologia 146 (1999), S. 117-120 
    Details
    ISSN: 1573-0832
    Keywords: antifungal susceptibility ; Candida albicans ; Candida spp. ; fluconazole ; Philippines ; resistance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Identification and fluconazole susceptibility of 579 yeasts isolated from patients in 16 medical centers throughout the Philippines in 1997–98 is reported. Speciation revealed the following distribution of yeasts (with percent occurrence): Candida albicans (49.6%); C. parapsilosis (17.2%);C. tropicalis (14.9%); C. glabrata(6.2%); C. pelliculosa (4.3%); C. krusei(2.4%); C. guilliermondii (1.9%); Trichosporon cutaneum (1.7%); Cryptococcus neoformans (0.9%); Candida famata (0.5%);C. lusitaniae (0.2%) and Saccharomyces cerevisiae (0.2%). Using an agar disk diffusion assay for fluconazole susceptibility it was determined that 94% of the isolates were susceptible, 5% dose-dependent susceptible and only 1% resistant. All isolates of C. albicans were susceptible (one being dose dependent sensitive) to fluconazole. The only yeasts resistant to fluconazole were: C. guillermondii (1 isolate), C. glabrata (3 isolates) and C. parapsilosis (1 isolate).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1007025212469
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    Paper (German National Licenses)
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