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  • Korea  (7)
  • permeability  (7)
  • Arabidopsis thaliana  (5)
  • Isothermal diffusion  (5)
  • Springer  (24)
  • American Geophysical Union (AGU)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of biomedical science 5 (1998), S. 267-273 
    ISSN: 1423-0127
    Keywords: Grave's disease ; Human foamy virus ; Korea ; Molecular epidemiology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The possible association of human foamy virus (HFV) with human thyroid disorders such as Graves' disease (GD) has been a topic of controversy due to the inconsistent results reported by several groups of investigators. Here we report the investigation of the presence of HFV-related sequences in the Korean population. DNA was obtained from peripheral blood lymphocytes from 24 GD patients and 23 healthy blood donors and subjected to PCR amplification using three sets of nested primers derived fromgag, env, and LTR regions of the HFV genome. Contrary to previously reported studies, our analysis identified HFV-related sequences in the genomes of both healthy individuals and the GD patients. However, the nature of the HFV genome present in each group appeared to be different. We detected all 3 regions of HFV-related sequences in 29% of the HFV-positive GD patients, while no samples in the control group amplified all three regions. This suggests that the LTR may be used as a tool for screening for HFV in GD patients. Our data favor the hypothesis of a relationship between GD and the presence of HFV-related sequences, though in a complex way.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-904X
    Keywords: drug delivery systems ; skin alternatives ; transdermal drug delivery ; permeability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Purpose. To test the barrier function of a bio-engineered human skin (BHS) using three model drugs (caffeine, hydrocortisone, and tamoxifen) in vitro. To investigate the lipid composition and microscopic structure of the BHS. Methods. The human skin substitute was composed of both epidermal and dermal layers, the latter having a bovine collagen matrix. The permeability of the BHS to three model drugs was compared to that obtained in other percutaneous testing models (human cadaver skin, hairless mouse skin, and EpiDerm™). Lipid analysis of the BHS was performed by high performance thin layered chromatrography. Histological evalulation of the BHS was performed using routine H&E staining. Results. The BHS mimicked human skin in terms of lipid composition, gross ultrastructure, and the formation of a stratum corneum. However, the permeability of the BHS to caffeine, hydrocortisone, and tamoxifen was 3-4 fold higher than that of human cadaver skin. Conclusions. In summary, the results indicate that the BHS may be an acceptable in vitro model for drug permeability testing.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Environmental geochemistry and health 17 (1995), S. 139-146 
    ISSN: 1573-2983
    Keywords: Metal contamination ; Seoul ; Korea
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Medicine
    Notes: Abstract To investigate the dispersion patterns and the characteristics of heavy metal contamination due to urbanisation and industrialisation, soils and dusts collected from the Seoul area were analysed for Cu, Pb, Zn and Cd. The metal concentrations in most soils and dusts are higher than the world averages. The pollution index ((Σ Metal concentrations in soils/Permissible level for metal)÷(Number of metals)) of soils and dusts is 〉 1 in most of the Seoul area, a result that concurs with the industrialisation and urbanisation index of the Seoul area. The soils are contaminated with Cu, Zn, Cd and particularly Pb. This suggests that the contamination of the soils in the Seoul area are mainly caused by vehicular emissions. The pollution index of soil is the highest in the Kuro area where Cu and Zn contamination in soils are due to the indigenous brass and bronze factories. From the discriminant analysis, the Seoul area may be partitioned into control, traffic and industrialized areas by the metal concentrations in the order of Zn 〉 Cu 〉 Pb.
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of solution chemistry 11 (1982), S. 347-355 
    ISSN: 1572-8927
    Keywords: Isothermal diffusion ; ternary system ; water-choline chloride-HCl ; synaptic gap
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Sets of four diffusion coefficients were obtained for the water-choline chloridehydrogen chloride system at 25°C. The cross-term diffusion coefficients were found to be very large, and the electrostatic force is the dominant factor for these cross-term diffusion coefficients.
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  • 5
    ISSN: 1572-8927
    Keywords: Isothermal diffusion ; diffusion coefficients ; aqueous solution ; ternary system ; Bu4NBr ; HBr ; primary charge effect ; activity coefficients
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Four diffusion coefficients for one composition of the system H2O-Bu4NBr-HBr were obtained at 25°C. The value of (D 12)v was negative and large as expected from the primary charge effect. However, the value of (D 21)v was also negative despite the fact that the primary charge effect predicts a positive value. This was interpreted to be a consequence of a large negative value for δ ln y2/δC1 which overshadows the primary charge effect.
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of solution chemistry 2 (1973), S. 477-488 
    ISSN: 1572-8927
    Keywords: Isothermal diffusion ; ternary system ; H2O-sucrose-KCl ; ionic mobility ; sucrose solution ; hydration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Diffusion coefficients were obtained for two compositions of the system H2O-sucrose-KCl at 25°C. These plus published diffusion coefficients of the same system at two other compositions led to the construction of three-dimensional surface diagrams. Using these diagrams, the diffusion coefficients of the ternary system were compared with those of binary systems of components. The main diffusion coefficient of KCl was estimated from the conductivity data of KCl in aqueous solution of sucrose, and the agreement of these with experimental values was found to be satisfactory. The possible cause for the appreciable size of the cross-term diffusion coefficients is discussed.
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  • 7
    ISSN: 1572-8927
    Keywords: Isothermal diffusion ; binary system ; ternary system ; water ; succinic acid ; urea ; complex formation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Sets of four diffusion coefficients at 25°C were obtained for four compositions of the system H2O-succinic acid-urea. The binary diffusion coefficients of succinic acid in water were also obtained at 25°C. The effect of possible complex formation between solutes on the diffusion coefficients of the ternary system is discussed.
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  • 8
    ISSN: 1572-8927
    Keywords: Isothermal diffusion ; aqueous solution ; ternary system ; tetrabutylammonium bromide ; potassium bromide ; ionic transport coefficients ; water structure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Sets of four diffusion coefficients were obtained for the water-tetrabutylammonium bromide-potassium bromide system at 25°C as a function of tetrabutylammonium bromide concentration with the mean concentration of potassiumbromide fixed at 0.1 mole-liter−1. The experiments were performed at tetrabutylammonium bromide concentrations of 0.075, 0.15, 0.3, and 0.45 mole-liter−1. The results are compared with the binary diffusion coefficients of these components and also with the calculated diffusion coefficients using the first approximation theory.
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Applied composite materials 1 (1994), S. 351-371 
    ISSN: 1573-4897
    Keywords: commingled yarn ; impregnation ; consolidation ; thermoplastics ; processing ; permeability ; mechanical testing ; mathematical modelling ; compression moulding ; glass fibre bed
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Impregnation mechanisms of different kinds of GF/PP commingled yarns have been studied. As the reinforcing fibres were always the same, a global description has been worked out. Two different mathematical approaches for fibre bed permeability (Kozeny-Carman and Gutowski) were compared. The constants of the applied mathematical models have to stay the same if the fibre reeinforcement and the fibre arrangement is the same. Neither the kind of matrix, nor the fibre volume content may change these constants. Differences in the degree of impregnation after the same process conditions can be only due to different sizes of fibre agglomerations, thus the initial distribution of reinforcing fibres and matrix. For an exact determination of impregnation times and conditions the exact distribution of fibres in the intermediate material and after processing has to be known. This distribution is determined by SEM microscopy and data given from the material supplier. The importance of different process parameters, such as temperature, pressure, processing time is weighted by determining the density and mechanical properties of the specimens.
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  • 10
    ISSN: 1573-5028
    Keywords: Arabidopsis thaliana ; cDNA ; gene expression ; starch biosynthesis ; starch branching enzyme
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Two starch branching enzyme (SBE) cDNAs were identified in an Arabidopsis seedling hypocotyl library using maize Sbe1 and Sbe2 cDNAs as probes. The two cDNAs have diverged 5′ and 3′ ends, but encode proteins which share 90% identity over an extensive region with 70% identity to maize SBE IIb [12]. Genomic Southern blots suggest that the two cDNAs are the products of single, independent genes, and that additional, more distantly related SBE genes may exist in the Arabidopsis genome. The two cDNAs hybridize to transcripts which show similar expression patterns in Arabidopsis vegetative and reproductive tissues, including seedlings, inflorescence rachis, mature leaves, and flowers. This is the first report of the identification of cDNAs encoding two closely related starch branching enzymes from the same species.
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