ALBERT

Description: Recently, an alternative robust control chart based on a new robust estimator known as minimum vector variance (MVV) estimator, , was introduced in Phase II. was able to detect out-of-control signal and simultaneously control false alarm rate even as the dimension increased. However, the estimated UCLs of are large as compared to the traditional chart. In this study, we improved the MVV estimators in terms of consistency and bias. The result showed great improvement in the control limit values while maintaining its good performance in terms of false alarm and probability of detection.

Description: Modular production and component commonality are two widely used strategies in the manufacturing industry to meet customers growing needs for customized products. Using these strategies, companies can enhance their performance to achieve optimal safety stock levels. Despite the importance of safety stocks in business competition, little attention has been paid to the way to reduce them without affecting the customer service levels. This paper develops a mathematical model to reduce safety stock levels in organizations that employ modular production. To construct the model, we take advantage of the benefits of aggregate inventories, standardization of components, component commonality, and Group Technology philosophy in regard to stock levels. The model is tested through the simulation of three years of operation of two modular product systems. For each system, we calculated and compared the safety stock levels for two cases: () under the only presence of component commonality and () under the presence of both component commonality and Group Technology philosophy. The results show a reduction in safety stock levels when we linked the component commonality with the Group Technology philosophy. The paper presents a discussion of the implications of each case, features of the model, and suggestions for future research.

Description: Many problems with control theory have led to investigations into switched systems. One of the most urgent problems related to the analysis of the dynamics of switched systems is the stability problem. The stability of a switched system can be ensured by a common Lyapunov function for all switching modes under an arbitrary switching law. Finding a common Lyapunov function is still an interesting and challenging problem. The purpose of the present paper is to prove the stability of equilibrium in a certain class of nonlinear switched systems by introducing a common Lyapunov function; the Lyapunov function is based on generalized Kullback–Leibler divergence or Csiszár's I-divergence between the state and equilibrium. The switched system is useful for finding positive solutions to linear algebraic equations, which minimize the I-divergence measure under arbitrary switching. One application of the stability of a given switched system is in developing a new approach to reconstructing tomographic images, but nonetheless, the presented results can be used in numerous other areas.

Description: The job shop scheduling problem (JSSP) is one of the well-known hard combinatorial scheduling problems. This paper proposes a hybrid genetic algorithm with multiparents crossover for JSSP. The multiparents crossover operator known as extended precedence preservative crossover (EPPX) is able to recombine more than two parents to generate a single new offspring distinguished from common crossover operators that recombine only two parents. This algorithm also embeds a schedule generation procedure to generate full-active schedule that satisfies precedence constraints in order to reduce the search space. Once a schedule is obtained, a neighborhood search is applied to exploit the search space for better solutions and to enhance the GA. This hybrid genetic algorithm is simulated on a set of benchmarks from the literatures and the results are compared with other approaches to ensure the sustainability of this algorithm in solving JSSP. The results suggest that the implementation of multiparents crossover produces competitive results.

Description: Key Points Statement on the importance of climate change politics

Description: Cognitive radio (CR) is considered nowadays as a strong candidate solution for the spectrum scarcity problem. On standards level, many cognitive radio standards have chosen Non-Contiguous Orthogonal Frequency Division Multiplexing (NC-OFDM) as their modulation scheme. Similar to OFDM, NC-OFDM suffers from the problem of having a high Peak to Average Power Ratio (PAPR). If not solved, either the transmitted signal will be distorted, which will cause interference to primary (licensed) users, or the effeciency of the power amplifier will be seriously degraded. The effect of the PAPR problem in NC-OFDM based cognitive radio networks is worse than normal OFDM systems. In this paper, we propose enhanced techniques to reduce the PAPR in NC-OFDM systems. We start by showing that combining two standard PAPR reduction techniques (interleaver-based and selective mapping) results in a lower PAPR than using them individually. Then, an “adaptive number of interleavers” will be proposed that achieves the same performance of conventional interleaver-based PAPR reduction while reducing the CPU time by 41.3%. Finally, adaptive joint interleaver with selective mapping is presented, and we show that it gives the same performance as conventional interleaver-based technique, with reduction in CPU time by a factor of 50.1%.

Description: Although human bitter taste perception is hypothesized to be a dietary adaptation, little is known about genetic signatures of selection and patterns of bitter taste perception variability in ethnically diverse populations with different diets, particularly from Africa. To better understand the genetic basis and evolutionary history of bitter taste sensitivity, we sequenced a 2,975 bp region encompassing TAS2R38 , a bitter taste receptor gene, in 611 Africans from 57 populations in West Central and East Africa with diverse subsistence patterns, as well as in a comparative sample of 132 non-Africans. We also examined the association between genetic variability at this locus and threshold levels of phenylthiocarbamide (PTC) bitterness in 463 Africans from the above populations to determine how variation influences bitter taste perception. Here, we report striking patterns of variation at TAS2R38 , including a significant excess of novel rare nonsynonymous polymorphisms that recently arose only in Africa, high frequencies of haplotypes in Africa associated with intermediate bitter taste sensitivity, a remarkably similar frequency of common haplotypes across genetically and culturally distinct Africans, and an ancient coalescence time of common variation in global populations. Additionally, several of the rare nonsynonymous substitutions significantly modified levels of PTC bitter taste sensitivity in diverse Africans. While ancient balancing selection likely maintained common haplotype variation across global populations, we suggest that recent selection pressures may have also resulted in the unusually high level of rare nonsynonymous variants in Africa, implying a complex model of selection at the TAS2R38 locus in African populations. Furthermore, the distribution of common haplotypes in Africa is not correlated with diet, raising the possibility that common variation may be under selection due to their role in nondietary biological processes. In addition, our data indicate that novel rare mutations contribute to the phenotypic variance of PTC sensitivity, illustrating the influence of rare variation on a common trait, as well as the relatively recent evolution of functionally diverse alleles at this locus.

Description: Aims. T2DM often remains undiagnosed for many years because hyperglycemia develops gradually and may not produce any symptoms. As patients with T2DM are at increased risk of microvascular and macrovascular complications, the preclinical diagnosis of the state is the key point of the disease management. Methods. We evaluated parameters such as GAGs/PGs, NAG, and NGAL in urine samples from 43 normoalbuminuric T2DM patients and 31 apparently healthy control subjects. Results. The total urinary GAG excretion showed no significant differences between patients and controls. The electrophoretic analysis evidenced the presence of UTI and its degradation products (LSC and SM-LSC), CS, and HS. We observed modifications of HS and total UTI (including UTI and its degradation products) relative contents in T2DM patients compared with controls whereas no differences in CS percentage were found. NGAL levels were significantly increased in T2DM patients and were positively correlated with both NAG (, ) and the presence of hypertension (, ). Conclusions. These data suggest that the assessed molecules could represent useful markers to detect early renal impairment in patients with T2DM.

Description: We represent proteins by amino acid interaction networks. This is a graph whose vertices are the proteins amino acids and whose edges are the interactions between them. Once we have compared this type of graphs to the general model of scale-free networks, we analyze the existence of nodes which highly interact, the hubs. We describe these nodes taking into account their position in the primary structure to study their apparition frequency in the folded proteins. Finally, we observe that their interaction level is a consequence of the general rules which govern the folding process.

Description: Over the recent past, the global market of electrical and electronic equipment (EEE) has grown exponentially, while the lifespan of these products has become increasingly shorter. More of these products are ending up in rubbish dumps and recycling centers, posing a new challenge to policy makers. The purpose of this paper is to provide a review of the e-Waste problem and to put forward an estimation technique to calculate the growth of e-Waste.