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  • Cell Press  (648)
  • American Geophysical Union  (646)
  • Nature Publishing Group  (537)
  • 1
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    Genome-wide Analyses Identify KIF5A as a Novel ALS Gene (2018)
    Cell Press
    Details
    Publication Date: 2018-03-01
    Print ISSN: 0896-6273
    Electronic ISSN: 1097-4199
    Topics: Biology , Medicine
    Published by Cell Press
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  • 2
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    Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes (2018)
    Cell Press
    Details
    Publication Date: 2018-06-01
    Print ISSN: 0092-8674
    Electronic ISSN: 1097-4172
    Topics: Biology , Medicine
    Published by Cell Press
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  • 3
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    Fractal landscapes and molecular evolution: modeling the myosin heavy chain gene family (1993)
    Cell Press
    Details
    Publication Date: 1993-12-01
    Print ISSN: 0006-3495
    Electronic ISSN: 1542-0086
    Topics: Biology , Physics
    Published by Cell Press
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  • 4
    Electronic Resource
    Electronic Resource
    Linkage-disequilibrium mapping without genotyping (1998)
    [s.l.] : Nature Publishing Group
    Nature genetics 18 (1998), S. 225-230 
    Details
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Genomic mismatch scanning (GMS) is a technique that enriches for regions of identity by descent (IBD) between two individuals without the need for genotyping or sequencing. Regions of IBD selected by GMS are mapped by hybridization to a microarray containing ordered clones of genomic DNA from ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/ng0398-225
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  • 5
    Electronic Resource
    Electronic Resource
    Scaling behaviour in the growth of companies (1996)
    [s.l.] : Nature Publishing Group
    Nature 379 (1996), S. 804-806 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The simplest model for corporate growth was proposed by Gibrat1. Its basic assumptions are that the rate of company growth is (1) independent of company size (law of proportionate effect), and (2) uncorrelated in time. These assumptions can be formalized by the following random multiplicative ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/379804a0
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  • 6
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    FOZO, HIMU, and the rest of the mantle zoo (2006)
    American Geophysical Union
    Details
    Publication Date: 2022-05-25
    Description: Author Posting. © American Geophysical Union, 2005. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Geochemistry Geophysics Geosystems 6 (2005): Q05007, doi:10.1029/2004GC000824.
    Description: The parameter μ describes the 238U/204Pb ratio of an Earth reservoir. Mantle domains labeled HIMU (high μ) originally defined reservoirs with highly radiogenic Pb isotope ratios observed in basalts from a select number of ocean islands, St. Helena in the Atlantic Ocean and the Cook-Austral islands in the South Pacific Ocean. While some authors use the term HIMU in this original sense, others refer to HIMU as a widespread component in many mid-ocean ridge and ocean island basalt (MORB and OIB) sources. Here we show that highly radiogenic Pb isotope signatures in MORB and OIB originate from two different sources. In addition to the classical HIMU component observed at St. Helena and the South Pacific (named HIMU in the following), we define a component with slightly less radiogenic Pb but significantly more radiogenic Sr isotope signatures. This component lies at the extension of the (Atlantic and Pacific) MORB array in a Sr-Pb isotope ratio diagram and is argued to be a ubiquitous component in MORB and many OIB sources. The inferred role of this component in the mantle and its inferred genetic origin closely resemble those originally suggested for a mantle component termed FOZO by Hart and coworkers. By redefining the composition, the origin, and the role of FOZO in the mantle, we establish a simple conceptual framework that explains the isotopic variability in both MORB and OIB with the lowest number of components. OIB are grouped into HIMU-type OIB and basalts from islands that diverge from the MORB-FOZO array toward various isotopically “enriched” compositions (EM). The apparent ubiquity of FOZO in the mantle and the calculated isotopic evolution of compositionally diverse MORB suggest that normal mantle melting and continuous subduction and aging of that crust during recycling through the mantle are the dominant causes of the MORB-FOZO array. In contrast to FOZO, HIMU-type OIB are quite rare, and if an origin by recycling of oceanic crust is also postulated, the production of HIMU sources has to be a special and rare combination of age and composition of subduction-modified recycled oceanic crust.
    Description: This work is partially supported by the Deutsche Forschungsgmeinschaft (DFG grant STR853/1 to A.S).
    Keywords: FOZO ; HIMU ; MORB ; Oceanic basalts ; OIB
    Repository Name: Woods Hole Open Access Server
    Type: Article
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  • 7
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    Hydrothermal venting at Vailulu'u Seamount : the smoking end of the Samoan chain (2006)
    American Geophysical Union
    Details
    Publication Date: 2022-05-25
    Description: Author Posting. © American Geophysical Union, 2004. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Geochemistry Geophysics Geosystems 5 (2004): Q02003, doi:10.1029/2003GC000626.
    Description: The summit crater of Vailulu'u Seamount, the youngest volcano in the Samoan chain, hosts an active hydrothermal system with profound impact on the ocean water column inside and around its crater (2 km wide and 407 m deep at a 593 m summit depth). The turbidity of the ocean water reaches 1.4 NTU, values that are higher than in any other submarine hydrothermal system. The water is enriched in hydrothermal Mn (3.8 ppb) and 3He (1 × 10−11 cc/g) and we measured water temperature anomalies near the crater floor up to 0.2°C. The hydrothermal system shows complex interactions with the ocean currents around Vailulu'u that include tidally-modulated vertical motions of about 40–50 m, and replenishment of waters into the crater through breaches in the upper half of the crater wall. Inside and outside potential density gradients suggest that hydrothermal venting exports substantial amounts of water from the crater (1.3 ± 0.2 × 108 m3/day), which is in good agreement with fluxes obtained from a tracer release experiment inside the crater of Vailulu'u (0.8 × 108 m3/day [Hart et al., 2003]). This mass flux, in combination with the differences in the inside and outside crater temperature, yields a power output of around 760 megawatts, the equivalent of 20–100 MOR black smokers. The Mn output of 300 kg/day is approximately ten times the output of a single black smoker.
    Repository Name: Woods Hole Open Access Server
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  • 8
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    A new automated method for measuring noble gases and their isotopic ratios in water samples (2010)
    American Geophysical Union
    Details
    Publication Date: 2022-05-25
    Description: Author Posting. © American Geophysical Union, 2009. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Geochemistry Geophysics Geosystems 10 (2009): Q05008, doi:10.1029/2009GC002429.
    Description: A method is presented for precisely measuring all five noble gases and their isotopic ratios in water samples using multiple programmed multistage cryogenic traps in conjunction with quadrupole mass spectrometry and magnetic sector mass spectrometry. Multiple automated cryogenic traps, including a two-stage cryotrap used for removal of water vapor, an activated charcoal cryotrap used for helium separation, and a stainless steel cryotrap used for neon, argon, krypton, and xenon separation, allow reproducible gas purification and separation. The precision of this method for gas standards is ±0.10% for He, ±0.14% for Ne, ±0.10% for Ar, ±0.14% for Kr, and ±0.17% for Xe. The precision of the isotopic ratios of the noble gases in gas standards are ±1.9‰ for 20Ne/22Ne, ±2.0‰ for 84Kr/86Kr, ±2.5‰ for 84Kr/82Kr, ±0.9‰ for 132Xe/129Xe, and ±1.3‰ for 132Xe/136Xe. The precision of this method for water samples, determined by measurement of duplicate pairs, is ±1% for He, ±0.9% for Ne, ±0.3% for Ar, ±0.3% for Kr, and ±0.2% for Xe. An attached magnetic sector mass spectrometer measures 3He/4He with precisions of ±0.1% for air standards and ±0.14% for water samples.
    Description: We are grateful for support by the National Science Foundation Chemical Oceanography program (OCE-0221247), by the Department of Defense (graduate fellowship to RHRS), and by the Woods Hole Oceanographic Institution (postdoctoral fellowship for B.B.).
    Keywords: Noble gas ; Oceanography ; Mass spectrometry ; Seawater ; Isotope ; Cryogenic
    Repository Name: Woods Hole Open Access Server
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  • 9
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    Noble gas constraints on air-sea gas exchange and bubble fluxes (2010)
    American Geophysical Union
    Details
    Publication Date: 2022-05-25
    Description: Author Posting. © American Geophysical Union, 2009. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research 114 (2009): C11020, doi:10.1029/2009JC005396.
    Description: Air-sea gas exchange is an important part of the biogeochemical cycles of many climatically and biologically relevant gases including CO2, O2, dimethyl sulfide and CH4. Here we use a three year observational time series of five noble gases (He, Ne, Ar, Kr, and Xe) at the Bermuda Atlantic Time series Study (BATS) site in tandem with a one-dimensional upper ocean model to develop an improved parameterization for air-sea gas exchange that explicitly includes separate components for diffusive gas exchange and bubble processes. Based on seasonal timescale noble gas data, this parameterization, which has a 1σ uncertainty of ±14% for diffusive gas exchange and ±29% for bubble fluxes, is more tightly constrained than previous parameterizations. Although the magnitude of diffusive gas exchange is within errors of that of Wanninkhof (1992), a commonly used parameterization, we find that bubble-mediated exchange, which is not explicitly included by Wanninkhof (1992) or many other formulations, is significant even for soluble gases. If one uses observed saturation anomalies of Ar (a gas with similar characteristics to O2) and a parameterization of gas exchange to calculate gas exchange fluxes, then the calculated fluxes differ by ∼240% if the parameterization presented here is used compared to using the Wanninkhof (1992) parameterization. If instead one includes the gas exchange parameterization in a model, then the calculated fluxes differ by ∼35% between using this parameterization and that of Wanninkhof (1992). These differences suggest that the bubble component should be explicitly included in a range of marine biogeochemical calculations that incorporate air-sea gas fluxes.
    Description: Funding from the National Science Foundation Chemical Oceanography program (OCE-0221247 and OCE-0623034).
    Keywords: Air-sea gas exchange ; Noble gas ; Bubbles
    Repository Name: Woods Hole Open Access Server
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  • 10
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    Domains of depleted mantle : new evidence from hafnium and neodymium isotopes (2011)
    American Geophysical Union
    Details
    Publication Date: 2022-05-25
    Description: Author Posting. © American Geophysical Union, 2011. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Geochemistry Geophysics Geosystems 12 (2011): Q08001, doi:10.1029/2011GC003617.
    Description: Isotope systematics of basalts provide information on the distribution of mantle components and the length scale of mantle heterogeneity. To obtain this information, high data and sampling density are crucial. We present hafnium and neodymium isotope data on more than 400 oceanic volcanics. Over length scales of several hundred to over one thousand kilometers hafnium and neodymium isotopes of mid-ocean ridge basalts are correlated and form an array of parallel trends on a global scale. On a larger scale these domains differ in the amount of highly depleted mantle material with radiogenic hafnium and neodymium isotope ratios. Compared to the Atlantic and Indian Ocean basins the asthenosphere of the Pacific basin seems to have a more uniform and a less radiogenic Hf isotopic composition for a given Nd isotopic composition. The parallel arrays of mid-ocean ridge basalts provide strong constraints on the makeup of the MORB mantle and are evidence for the presence of a highly depleted and highly radiogenic neodymium and hafnium component. This component, because of its highly depleted character, is unrecognized in the strontium-neodymium-lead isotope systems alone. Alternatively, the parallel arrays can have an ancient origin of systematic variations in the degree of depletion. Each array then represents the variations in this fossil melting regime. Individual ocean island basalt suites display different slopes in hafnium-neodymium isotope space, which are also best explained by varying amounts of highly residual mantle rather than isotopic differences in enriched mantle components as previously invoked. The ocean island basalt arrays diverge at the depleted end and project to radiogenic compositions that are similar to those of the asthenosphere through which they travel. This is strong evidence that the plume material interacts with its surrounding mantle as it ascends. The isotopic compositions of the ocean island and ridge basalts suggest that their systematics are influenced by a heretofore unrecognized depleted component.
    Description: This work was supported by NSF grants EAR 0635864 and OCE0648484 to V.S. and OCE0351437 to S.H.
    Keywords: MORB ; Hafnium ; Isotopes ; Neodymium
    Repository Name: Woods Hole Open Access Server
    Type: Article
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