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  • Springer  (58)
  • American Geophysical Union  (14)
  • Geological Society of America  (5)
  • Blackwell Publishing Ltd  (4)
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  • 1
    Electronic Resource
    Electronic Resource
    Effects of Substance P on Secretion of Catecholamines from Populations of Bovine Chromaffin Cells and on Calcium Transients in Individual Cells (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 632 (1991), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1991.tb33112.x
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  • 2
    Electronic Resource
    Electronic Resource
    PURIFICATION AND PROPERTIES OF α-1, 4-GLUCAN PHOSPHORYLASE FROM SWEET CORN (1973)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 210 (1973), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1973.tb47566.x
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  • 3
    Electronic Resource
    Electronic Resource
    Soluble Carbohydrates in the Bark of Italian Prune (Prunus domestica) Trees (1971)
    Oxford, UK : Blackwell Publishing Ltd
    Physiologia plantarum 24 (1971), S. 0 
    Details
    ISSN: 1399-3054
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Bark samples were removed from 1-year-old stems of Italian prune trees at intervals throughout the growing season (June–August). Glucose, fructose, sucrose, traces of raffinose and a polyol were detected in ethanolic extracts of the bark. The polyol was isolated and shown to be d-glucitol. The use of insoluble polyvinylpyrrolidone proved to be the best method for decolorizing bark extracts prior to quantitative analysis of ethanol-soluble carbohydrates by paper chromato-graphic methods. Glucitol was the major carbohydrate in the bark throughout the season. Sucrose was the major sugar, decreasing gradually as the season advanced. Fructose and glucose were found in lesser and about equal amounts. The amount of glucitol, glucose and fructose was high in June, decreased to a minimum in mid-July, increased sharply in late July and early August and decreased later in the season.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1399-3054.1971.tb03481.x
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  • 4
    Electronic Resource
    Electronic Resource
    Learning of “Single Trial” and “Contextual” Information Processing in an Odd-Ball Paradigm (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 425 (1984), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1984.tb23527.x
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  • 5
    Electronic Resource
    Electronic Resource
    Thermal decomposition of tetraethoxysilane (TEOS) on Si(111)-(7×7) (1998)
    Springer
    Applied physics 66 (1998), S. 1021-1024 
    Details
    ISSN: 1432-0630
    Keywords: PACS: 68.35.Bs; 68.35.Dv; 82.65.My
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: 2 formation by chemical vapor deposition, on Si(111)-(7×7). Annealing after predominantly dissociative adsorption at room temperature, where triethoxysiloxane and ethyl groups are the main adsorbate species, leads to further decomposition with various products evolving, including diethoxysiloxane and further ethyl groups. This goes along with structural changes on the (7×7) reconstructed surface. A characteristic new structural element, with a maximum on interstitial sites, is interpreted as the very beginning of surface oxide formation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/
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  • 6
    Electronic Resource
    Electronic Resource
    Freezing in forced convection flows inside ducts: A review (1997)
    Springer
    Heat and mass transfer 32 (1997), S. 341-351 
    Details
    ISSN: 1432-1181
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Description / Table of Contents: Zusammenfassung Die vorliegende Arbeit gibt einen Überblick über aktuelle Forschungsentwicklungen auf dem Gebiet des Gefrierens in durchströmten Kanälen. Der Schwerpunkt wird auf die grundsätzlichen Aspekte gelegt, die sowohl bei den beobachteten Gefriervorgängen selbst, als auch bei deren analytischer oder numerischer Modellierung von Bedeutung sind. Der Artikel befaßt sich mit Gefriervorgängen in Rohren, zwischen parallelen Platten, gekrümmten, rechteckigen Kanälen und divergenten, rechteckigen Kanälen. Darüberhinaus werden einige aktuelle Ergebnisse beim Erstarren von Wasser in Kanalströmungen aus den laufenden Forschungsarbeiten in Darmstadt vorgestellt.
    Notes: Abstract The present work gives an overview about the recent developments in research on freezing phenomena in forced convection flows inside ducts. Emphasis is given to the fundamental aspects of the phenomena observed in the solidification processes as well as on the analytical and numerical modelling aspects for this kind of problems. The paper deals with solidification problems inside tubes, parallel plate channels, curved rectangular channels and in diverging rectangular channels. Additionally, some new experimental and numerical results on solidification in duct flows are shown from the current research program in Darmstadt on freezing phenomena.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002310050131
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  • 7
    Electronic Resource
    Electronic Resource
    Bioavailability of disopyramide in normal volunteers using unbound concentration (1987)
    Springer
    European journal of clinical pharmacology 32 (1987), S. 625-629 
    Details
    ISSN: 1432-1041
    Keywords: disopyramide ; bioavailability ; saturable binding ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetics of disopyramide were determined in 10 healthy volunteers after a 300 mg oral dose and again after a 2mg/kg i.v. dose. The unbound clearance was 599 ml/min and the unbound renal clearance 310 ml/min. The terminal elimination rate constant of unbound drug was 0.180 h−1 after the i.v. dose and 0.203 h−1 after the oral dose. The absorption rate constant was 0.53−1 and the maximum peak concentration occurred after 3.2 h. The bioavailability was 0.809 using the area under the unbound plasma concentration time curve. Although a saturable plasma protein binding was found in all subjects the bioavailability using the total concentration, in contrast to theoretical expectations, showed the same value (0.813) as the unbound concentrations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02456000
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  • 8
    Electronic Resource
    Electronic Resource
    Does alpha1-acid glycoprotein reduce the unbound metabolic clearance of disopyramide in patients with renal impairment? (1988)
    Springer
    European journal of clinical pharmacology 35 (1988), S. 313-317 
    Details
    ISSN: 1432-1041
    Keywords: disopyramide ; alpha1-acid glycoprotein ; renal dysfunction ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetics of disopyramide was studied in 15 patients with renal dysfunction (4 with pyelonephritis, 7 with glomerular nephritis and 4 with interstitial nephritis). The elimination rate constant of unbound disopyramide was 0.094 h−1 and CLu/f (unbound clearance divided by bioavailability) was 245 ml/min. Both the unbound renal clearance (CLR) and CLu/f were highly correlated with the creatinine clearance (CLCR). The apparent unbound metabolic clearance in the patients was approximately two-fold lower than that previously reported in normal subjects. The estimated unbound metabolic clearance in the renal dysfunction patients showed a significant negative correlation with the α1-acid glycoprotein (AAG) concentration and only a weak, non-significant correlation with CLCR. As AAG in the renal dysfunction subjects was increased in comparison with normal values, it is possible that AAG is a factor in the decrease in the apparent unbound metabolic clearance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00558271
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  • 9
    Electronic Resource
    Electronic Resource
    Pharmacokinetics of flecainide in patients with mild and moderate renal failure compared with patients with normal renal function (1987)
    Springer
    European journal of clinical pharmacology 31 (1987), S. 711-714 
    Details
    ISSN: 1432-1041
    Keywords: flecainide ; pharmacokinetics ; moderate renal failure ; variability of elimination half-time
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary We have studied the pharmacokinetics of flecainide after the oral administration of 100 mg to 8 patients without renal impairment and 8 patients with mild to moderate renal failure. Both groups gave comparable results with respect to the peak plasma concentrations and the time to peak. There was a significant correlation between renal flecainide clearance and endogenous creatinine clearance. The elimination half-time in the patients with impaired renal function was significantly longer (19.9, SD 9.9 h) than that in the patients with normal renal function (11.5, SD 4.2 h), but the variability in the elimination half-time in renal failure could not be explained on the basis of the available results.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00541300
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  • 10
    Electronic Resource
    Electronic Resource
    Pharmacokinetics of tocainide in patients with severe renal failure (1985)
    Springer
    European journal of clinical pharmacology 28 (1985), S. 665-670 
    Details
    ISSN: 1432-1041
    Keywords: tocainide ; renal failure ; pharmacokinetics ; oral dosing ; pharmacodynamics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The plasma levels of tocainide have been followed after oral administration of 600 mg p.o. to 20 patients with renal failure due to various causes, and to 8 healthy controls. The peak plasma concentrations in the patients with pyelonephritis (3.80 µg/ml) and interstitial nephritis (3.74 µg/ml) but not in those with glomerulonephritis (3.17 µg/ml) differed from that in healthy volunteers (3.24 µg/ml). The renal clearance of tocainide was well correlated with the endogenous creatinine clearance and was dependent on urine pH. No difference in renal clearance was observed between the patients groups. It is suggested that the changes in plasma levels are a consequence of decreased renal clearance. Creatinine clearance was shown to be a poor estimator of tocainide clearance, which suggests that extrarenal clearance plays an important role in the handling of the drug in the body. The findings are used to suggest a safe dosage regimen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00607912
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