Publication Date:
2001-11-24
Description:
Arylboron compounds have intriguing properties and are important building blocks for chemical synthesis. A family of Ir catalysts now enables the direct synthesis of arylboron compounds from aromatic hydrocarbons and boranes under "solventless" conditions. The Ir catalysts are highly selective for C-H activation and do not interfere with subsequent in situ transformations, including Pd-mediated cross-couplings with aryl halides. By virtue of their favorable activities and exceptional selectivities, these Ir catalysts impart the synthetic versatility of arylboron reagents to C-H bonds in aromatic and heteroaromatic hydrocarbons.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cho, Jian-Yang -- Tse, Man Kin -- Holmes, Daniel -- Maleczka, Robert E Jr -- Smith, Milton R 3rd -- R01 GM63188-01/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2002 Jan 11;295(5553):305-8. Epub 2001 Nov 22.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Chemistry, Michigan State University, East Lansing, MI 48824, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11719693" target="_blank"〉PubMed〈/a〉
Keywords:
Boron Compounds/*chemical synthesis/*chemistry
;
Carbon/*chemistry
;
Catalysis
;
Chemistry, Physical
;
Hydrocarbons, Aromatic/*chemical synthesis/*chemistry
;
Hydrogen/*chemistry
;
Iridium/*chemistry
;
Ligands
;
Physicochemical Phenomena
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
Permalink
