Publication Date:
2008-03-29
Description:
The past few years have revealed that the genomes of all studied eukaryotes are almost entirely transcribed, generating an enormous number of non-protein-coding RNAs (ncRNAs). In parallel, it is increasingly evident that many of these RNAs have regulatory functions. Here, we highlight recent advances that illustrate the diversity of ncRNA control of genome dynamics, cell biology, and developmental programming.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Amaral, Paulo P -- Dinger, Marcel E -- Mercer, Tim R -- Mattick, John S -- New York, N.Y. -- Science. 2008 Mar 28;319(5871):1787-9. doi: 10.1126/science.1155472.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute for Molecular Bioscience, University of Queensland, St. Lucia QLD 4072, Australia.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/18369136" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Eukaryotic Cells/*metabolism
;
Evolution, Molecular
;
*Gene Expression Regulation
;
Genome
;
Genome, Human
;
Humans
;
Protein Biosynthesis
;
RNA Processing, Post-Transcriptional
;
RNA, Untranslated/*genetics/metabolism
;
Transcription, Genetic
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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