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  • Cells, Cultured  (3)
  • Mice, Transgenic  (3)
  • *Body Weight  (2)
  • American Association for the Advancement of Science (AAAS)  (8)
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Keywords
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Years
  • 1
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    Obesity research. Tracing leptin's partners in regulating body weight (2001)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2001-02-07
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gura, T -- New York, N.Y. -- Science. 2000 Mar 10;287(5459):1738-41.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10755923" target="_blank"〉PubMed〈/a〉
    Keywords: Adipocytes/metabolism ; Animals ; Appetite/physiology ; *Body Weight ; Carrier Proteins/genetics/metabolism ; Humans ; Hypothalamic Hormones/genetics/physiology ; Hypothalamus/*physiology ; Leptin/genetics/metabolism/*physiology ; Melanins/genetics/physiology ; Muscles/metabolism ; Neuropeptide Y/genetics/physiology ; Neuropeptides/physiology ; Obesity/genetics/*physiopathology ; Pituitary Hormones/genetics/physiology ; Pro-Opiomelanocortin/genetics/physiology ; Proteins/genetics/physiology ; *Receptors, Cell Surface ; Receptors, Leptin ; *Repressor Proteins ; Suppressor of Cytokine Signaling Proteins ; *Transcription Factors ; alpha-MSH/genetics/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Obesity research. Pot-bellied mice point to obesity enzyme (2001)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2001-12-12
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gura, T -- New York, N.Y. -- Science. 2001 Dec 7;294(5549):2071-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11739926" target="_blank"〉PubMed〈/a〉
    Keywords: 11-beta-Hydroxysteroid Dehydrogenase Type 2 ; Abdomen ; Adipose Tissue/*enzymology/metabolism ; Animals ; Body Composition ; Diabetes Mellitus/enzymology/metabolism ; Enzyme Inhibitors/pharmacology ; Humans ; Hydrocortisone/blood/*metabolism ; Hydroxysteroid Dehydrogenases/antagonists & inhibitors/genetics/*metabolism ; Hypoglycemic Agents/pharmacology ; Male ; Metabolic Syndrome X ; Mice ; Mice, Transgenic ; Obesity/*enzymology/genetics/metabolism ; Skin
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Neurobiology. Trigger found for synapse formation (2000)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2000-07-06
    Description: Until now, neurobiologists have had little luck in finding the matchmakers of nerve cell connections, called synapses, in the brain. In today's issue of Cell, researchers report that a single protein can apparently trigger synapse formation between brain neurons isolated from mice and grown in culture. If the finding is borne out in living animals, it could provide fresh insights into how the brain is wired during embryonic development and might eventually provide new ways to enhance or at least maintain synapse formation in the brains of patients suffering from neurodegenerative diseases such as Parkinson's or Alzheimer's.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gura, T -- New York, N.Y. -- Science. 2000 Jun 9;288(5472):1718-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10877681" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Brain/cytology ; Cell Adhesion Molecules, Neuronal ; Cells, Cultured ; Membrane Proteins/analysis/genetics/*metabolism ; Mice ; Mice, Knockout ; Nerve Tissue Proteins/analysis/genetics/*metabolism ; Neurons/*physiology ; Synapses/*physiology ; Synaptic Membranes/chemistry
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Cancer research. Caution raised about possible new drug (2000)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2000-05-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gura, T -- New York, N.Y. -- Science. 2000 May 5;288(5467):786-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10809641" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antineoplastic Agents/*pharmacology ; *Apoptosis ; Apoptosis Regulatory Proteins ; Cell Death ; Cells, Cultured ; Clinical Trials as Topic ; Culture Techniques ; Drug Screening Assays, Antitumor ; Humans ; Liver/cytology/*drug effects ; Liver Diseases/pathology ; Membrane Glycoproteins/*pharmacology ; Neoplasms/*drug therapy/pathology ; TNF-Related Apoptosis-Inducing Ligand ; Tumor Necrosis Factor-alpha/*pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    From fat-free mice, the skinny on diabetes (1998)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1998-12-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gura, T -- New York, N.Y. -- Science. 1998 Oct 23;282(5389):604.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9841407" target="_blank"〉PubMed〈/a〉
    Keywords: Adipose Tissue/*physiology ; Animals ; Chromans/therapeutic use ; Diabetes Mellitus, Type 2/drug therapy/*etiology/physiopathology ; Fatty Acids/metabolism ; Humans ; Hypoglycemic Agents/therapeutic use ; Lipodystrophy/drug therapy ; Mice ; Mice, Transgenic ; Thiazoles/therapeutic use ; *Thiazolidinediones ; Transcription Factors/genetics/physiology ; Triglycerides/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Uncoupling proteins provide new clue to obesity's causes (1998)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1998-06-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gura, T -- New York, N.Y. -- Science. 1998 May 29;280(5368):1369-70.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9634415" target="_blank"〉PubMed〈/a〉
    Keywords: Adenosine Triphosphate/metabolism ; Adipocytes/metabolism ; Animals ; *Body Weight ; Carrier Proteins/genetics/*metabolism ; *Energy Metabolism ; Humans ; Ion Channels ; Membrane Proteins/genetics/*metabolism ; *Membrane Transport Proteins ; Mitochondria/metabolism ; *Mitochondrial Proteins ; Muscles/metabolism ; Obesity/*etiology/genetics/metabolism ; Oxygen Consumption ; Polymorphism, Genetic ; Proteins/genetics/*metabolism ; Uncoupling Agents/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    Mouse model for pregnancy problem? (1996)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1996-11-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gura, T -- New York, N.Y. -- Science. 1996 Nov 8;274(5289):922.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8966572" target="_blank"〉PubMed〈/a〉
    Keywords: Angiotensin II/metabolism ; Angiotensinogen/genetics/metabolism ; Animals ; Blood Pressure ; Crosses, Genetic ; *Disease Models, Animal ; Female ; Humans ; *Hypertension/physiopathology ; Male ; Mice ; Mice, Transgenic ; Placenta/metabolism ; Pregnancy ; *Pregnancy Complications, Cardiovascular/physiopathology ; Renin/genetics/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 8
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    Causing cancer by remote control? (1997)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1997-06-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gura, T -- New York, N.Y. -- Science. 1997 Jun 20;276(5320):1788-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9206838" target="_blank"〉PubMed〈/a〉
    Keywords: Bone Marrow/pathology/virology ; Cells, Cultured ; Dendritic Cells/*virology ; Herpesvirus 8, Human/metabolism/*pathogenicity ; Humans ; Interleukin-6/*biosynthesis/genetics ; Multiple Myeloma/pathology/*virology ; Paraproteinemias/pathology ; Polymerase Chain Reaction ; RNA, Messenger/analysis/genetics ; Sarcoma, Kaposi/virology ; Stromal Cells/metabolism/virology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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