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  • Geological Society of America (GSA)  (10)
  • American Association for the Advancement of Science (AAAS)  (4)
  • 1
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    Orocline formation at the core of Pangea: A structural study of the Cantabrian orocline, NW Iberian Massif (2016)
    Geological Society of America (GSA)
    Details
    Publication Date: 2016-01-20
    Print ISSN: 1941-8264
    Electronic ISSN: 1947-4253
    Topics: Geosciences
    Published by Geological Society of America (GSA)
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  • 2
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    Differentiating Shawinigan and Ottawan orogenesis in the Central Adirondacks (2011)
    Geological Society of America (GSA)
    Details
    Publication Date: 2011-02-01
    Description: The rocks at Chimney Mountain provide a rare glimpse into primary intrusive relations and exceptionally well-preserved pre-Shawinigan metasedimentary rocks in the Adirondack Highlands despite a strong Ottawan thermal overprint. A near vertical contact between granite (ca. 1172 Ma) and a shallowly dipping and structurally intact sequence of quartzose to calc-silicate metasedimentary rocks is exposed on the southern flank of Chimney Mountain in the Central Adirondacks. The contact is marked by foliation truncation and a metasomatic aureole with randomly orientated porphyroblasts of enstatite rimmed by anthophyllite (max. 5 cm) and phlogopite (max. 2 cm), and a zone of granular, quartz-rich rock. The granite is non- to weakly foliated and has a shallow, north-plunging, mineral lineation as do the metasedimentary rocks. Zircons separated from a diopside-bearing quartzite (82% SiO2; 0.75 m thick) are of variable size (up to 400 {micro}m), equant, and contain, on average, 〉1000 ppm uranium. Scanning electron microscope investigation indicates that there is little variation in a uniformly dark cathodoluminescence response, no discernible cores or rims, few inclusions, and partially faceted to round morphologies. Zircon U-Pb sensitive high-resolution ion microprobe (SHRIMP II) ages of 1042 {+/-} 4 Ma and 1073 {+/-} 15 Ma are coincident with Ottawan metamorphic ages from the Adirondack Highlands. Zircons from the intrusive granite yield large cores with typical anorthosite-mangerite-charnockite-granite (AMCG) ages (ca. 1171.6 {+/-} 6.3 Ma) and sparse, thin younger rims (ca. 1060-1090 Ma) readily distinguishable by cathodoluminescence. Despite the younger zircon ages, the metasedimentary rocks and their fabric must predate the crosscutting granite. The thermal effect of the Ottawan event was likely enhanced by volatile fluxing and resulted in recrystallization and resetting of zircons in the metasedimentary rocks. However, it had limited effects on zircons in the granite and produced only thin metamorphic rims emphasizing the importance of local geochemical conditions to the response of zircon to metamorphism. Elzevirian or Shawinigan fabrics are preserved as the dominant foliation; the lineation and folding is likely late (post-1170 Ma) Shawinigan or Ottawan (ca. 1050 Ma). Titanites from the same metasedimentary sequence yield a range of 238U/206Pb ages from 969 to 1077 Ma, with a maximum probability age of 1035 Ma, similar to other titanites in the Adirondack Highlands. Ottawan paleotemperatures, estimated by zirconium in titanite thermometry, range from 787 to 818 {degrees}C.
    Electronic ISSN: 1553-040X
    Topics: Geosciences
    Published by Geological Society of America (GSA)
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  • 3
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    Provenance variability along the Early Ordovician north Gondwana margin: Paleogeographic and tectonic implications of U-Pb detrital zircon ages from the Armorican Quartzite of the Iberian Variscan belt (2014)
    Geological Society of America (GSA)
    Details
    Publication Date: 2014-05-03
    Description: Detrital zircon laser ablation–inductively coupled plasma–mass spectrometry U-Pb age data from the Lower Ordovician Armorican Quartzite (deformed passive margin strata of Gondwanan affinity) of the Iberian Massif are presented herein. The S -shaped coupled Iberian oroclines defined within these zones palinspastically restore to a 2300 km linear Variscan orogen with a paleomagnetically constrained Late Carboniferous north-south trend. Detrital zircons are used to assess paleogeography and interpreted geometry of the Iberian portion of the Gondwana passive margin. A common signature is identified by (1) Neoproterozoic (ca. 500–850 Ma), (2) Stenian–Tonian (ca. 0.9–1.1 Ga), and lesser (3) Paleoproterozoic and (4) Archean populations (ca. 1.8–2.15 and 2.5–2.7 Ga, respectively). Minor site-to-site variation in relative proportion of widely ranging age groups suggests near-uniform distribution of a highly varied detrital input. Provenance analysis reveals strong correlations with Cambro-Ordovician clastic rocks from northeast African realms. Similarity with underlying sequences suggests a common paleogeography from the Ediacaran through early Paleozoic and persistence of a provenance distinction within the autochthonous Iberian Massif. Consistent northward paleoflow within widespread northeast African lower Paleozoic sedimentary cover suggests long-distance sedimentary transport across a North African peneplain from outlying basement terranes. We propose that the 2300-km-long Cantabrian–Central Iberian portion of the early Paleozoic Gondwana margin stretched east-west along the northern limits of the then low-lying Saharan Metacraton and Arabian-Nubian Shield. Accepting paleomagnetic constraints, a 90° counterclockwise rotation is required to reorient the Iberian portion to a pre-oroclinal (Late Carboniferous) north-south trend. The mechanisms for accommodating such a rotation are unclear.
    Print ISSN: 0016-7606
    Electronic ISSN: 1943-2674
    Topics: Geosciences
    Published by Geological Society of America (GSA)
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  • 4
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    Home ground advantage: Local Atlantic salmon have higher reproductive fitness than dispersers in the wild (2019)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2019
    Description: 〈p〉A long-held, but poorly tested, assumption in natural populations is that individuals that disperse into new areas for reproduction are at a disadvantage compared to individuals that reproduce in their natal habitat, underpinning the eco-evolutionary processes of local adaptation and ecological speciation. Here, we capitalize on fine-scale population structure and natural dispersal events to compare the reproductive success of local and dispersing individuals captured on the same spawning ground in four consecutive parent-offspring cohorts of wild Atlantic salmon (〈i〉Salmo salar〈/i〉). Parentage analysis conducted on adults and juvenile fish showed that local females and males had 9.6 and 2.9 times higher reproductive success than dispersers, respectively. Our results reveal how higher reproductive success in local spawners compared to dispersers may act in natural populations to drive population divergence and promote local adaptation over microgeographic spatial scales without clear morphological differences between populations.〈/p〉
    Electronic ISSN: 2375-2548
    Topics: Natural Sciences in General
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Oroclines: Thick and thin (2013)
    Geological Society of America (GSA)
    Details
    Publication Date: 2013-05-03
    Description: An orocline is a thrust belt or orogen that is curved in map-view due to it having been bent or buckled about a vertical axis of rotation. Two distinct types of oroclines are recognized: progressive and secondary. Progressive oroclines are restricted to the scale of a thrust sheet to thrust belt, are thin-skinned, and develop during thrust sheet emplacement. Secondary oroclines are larger, occurring at the scale of an orogen, and are plate-scale features that affect crust and lithospheric mantle. Unlike progressive oroclines, which develop during initial orogenesis and in response to the same orogen-perpendicular stress responsible for thrust sheet emplacement, secondary oroclines are extra-orogenic, developing after initial orogenesis and in response to an orogen-parallel principal compressive stress that is oriented at a high angle to the stress responsible for orogen development. We present case studies of the Wyoming Salient, a progressive orocline that characterizes the Sevier thrust belt of the western United States, and the coupled Cantabrian and Central Iberian oroclines, which are linked secondary oroclines affecting the Variscan orogen of Iberia. The vertical-axis rotations involved in progressive and secondary orocline formation are most readily quantified through paleomagnetic analysis. Detailed three-dimensional palinspastic restoration that incorporates translation rotation and strain can distinguish the role, if any, of primary curvature in progressive oroclines. The use of tectonic vectors, such as paleocurrent directions, provides a means of recognizing and characterizing the initial geometry of secondary oroclines. Because secondary oroclines involve the entire lithosphere, detailed studies of coeval metamorphism and magmatism provide a means of constraining the fate of the mantle lithosphere during oroclinal buckling.
    Print ISSN: 0016-7606
    Electronic ISSN: 1943-2674
    Topics: Geosciences
    Published by Geological Society of America (GSA)
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  • 6
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    Vomocytosis of live pathogens from macrophages is regulated by the atypical MAP kinase ERK5 (2017)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2017-08-17
    Description: Vomocytosis, or nonlytic extrusion, is a poorly understood process through which macrophages release live pathogens that they have failed to kill back into the extracellular environment. Vomocytosis is conserved across vertebrates and occurs with a diverse range of pathogens, but to date, the host signaling events that underpin expulsion remain entirely unknown. We use a targeted inhibitor screen to identify the MAP kinase ERK5 as a critical suppressor of vomocytosis. Pharmacological inhibition or genetic manipulation of ERK5 activity significantly raises vomocytosis rates in human macrophages, whereas stimulation of the ERK5 signaling pathway inhibits vomocytosis. Lastly, using a zebrafish model of cryptococcal disease, we show that reducing ERK5 activity in vivo stimulates vomocytosis and results in reduced dissemination of infection. ERK5 therefore represents the first host signaling regulator of vomocytosis to be identified and a potential target for the future development of vomocytosis-modulating therapies.
    Electronic ISSN: 2375-2548
    Topics: Natural Sciences in General
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine (2017)
    American Association for the Advancement of Science (AAAS)
    In: Science
    Details
    Publication Date: 2017-09-15
    Description: Growing evidence suggests that microbes can influence the efficacy of cancer therapies. By studying colon cancer models, we found that bacteria can metabolize the chemotherapeutic drug gemcitabine (2',2'-difluorodeoxycytidine) into its inactive form, 2',2'-difluorodeoxyuridine. Metabolism was dependent on the expression of a long isoform of the bacterial enzyme cytidine deaminase (CDD L ), seen primarily in Gammaproteobacteria. In a colon cancer mouse model, gemcitabine resistance was induced by intratumor Gammaproteobacteria, dependent on bacterial CDD L expression, and abrogated by cotreatment with the antibiotic ciprofloxacin. Gemcitabine is commonly used to treat pancreatic ductal adenocarcinoma (PDAC), and we hypothesized that intratumor bacteria might contribute to drug resistance of these tumors. Consistent with this possibility, we found that of the 113 human PDACs that were tested, 86 (76%) were positive for bacteria, mainly Gammaproteobacteria.
    Keywords: Medicine, Diseases
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 8
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    Numerical evidence of fluctuating stripes in the normal state of high-Tc cuprate superconductors (2017)
    American Association for the Advancement of Science (AAAS)
    In: Science
    Details
    Publication Date: 2017-12-01
    Description: Upon doping, Mott insulators often exhibit symmetry breaking where charge carriers and their spins organize into patterns known as stripes. For high–transition temperature cuprate superconductors, stripes are widely suspected to exist in a fluctuating form. We used numerically exact determinant quantum Monte Carlo calculations to demonstrate dynamical stripe correlations in the three-band Hubbard model, which represents the local electronic structure of the copper-oxygen plane. Our results, which are robust to varying parameters, cluster size, and boundary conditions, support the interpretation of experimental observations such as the hourglass magnetic dispersion and the Yamada plot of incommensurability versus doping in terms of the physics of fluctuating stripes. These findings provide a different perspective on the intertwined orders emerging from the cuprates’ normal state.
    Keywords: Physics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 9
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    Age, construction, and exhumation of the midcrust of the Jurassic Bonanza arc, Vancouver Island, Canada (2013)
    Geological Society of America (GSA)
    Details
    Publication Date: 2013-01-25
    Description: We present new U-Pb zircon ages for heterogeneous mafic-felsic rocks of the West Coast complex, a midcrustal plutonic component of exposed Jurassic arc-crustal section on Vancouver Island. We examine the timing of juvenile plutonic crust production, and consanguinity of volcanism and plutonism in this arc. The midcrustal plutons were emplaced between 193 Ma and 174 Ma, contemporaneous with the upper-crustal (〈10 km depth) plutonic component of the arc (Island plutonic suite). A 12 km thickness of plutonic arc crust was built as a series of sheets at a rate of ~0.003 km 3 yr –1 . Deformation and emplacement were contemporaneous, and there are no correlations among age, differentiation (peridotite to granite), or structural level of plutons in the arc. The age range and a weak eastward younging age polarity of the Jurassic arc section on Vancouver Island match that of the Talkeetna arc-crustal section in Alaska, suggesting that the two arcs are correlative and evolved by either forearc erosion above of an east-dipping slab, or slab rollback during west-dipping subduction.
    Print ISSN: 1941-8264
    Electronic ISSN: 1947-4253
    Topics: Geosciences
    Published by Geological Society of America (GSA)
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  • 10
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    Geochemistry and geochronology of the 1.3 Ga metatonalites from the Central Metasedimentary Belt boundary thrust zone in southern Ontario, Grenville Province, Canada (2013)
    Geological Society of America (GSA)
    In: Geosphere
    Details
    Publication Date: 2013-08-02
    Description: Studies of pre-Grenvillian (1.4–1.3 Ga) plutons offer insight into the dynamics of arc amalgamation and backarc rifting prior to continental collision during the Ottawan orogeny. The Central Metasedimentary Belt boundary thrust zone (CMBbtz) is a northeast-southwest–trending thrust zone consisting of metaplutonic thrust sheets enveloped in gneissic tectonites and calcitic-dolomitic marble. Tonalitic CMBbtz thrust sheets (Dysart and Redstone), located in the southern Ontario Grenville Province (Canada) are made up of upper amphibolite facies, foliation-concordant metatonalite (+ amphibole ± biotite ± accessory zircon and titanite) and amphibolite (± biotite ± clinopyroxene). These thrust sheets are thought to have formed and amalgamated onto the Laurentian margin prior to Ottawan orogeny. Major and trace element analyses show that the metatonalite rocks have calc-alkaline affinity and amphibolite rocks have both calc-alkaline and tholeiitic affinities, suggesting an arc environment. Laser ablation–inductively coupled plasma–mass spectrometry (LA-ICP-MS) geochronology of zircon from the two thrust sheets yield igneous ages of ca. 1350–1300 Ma for diorite and granodiorite, ca. 1150–1100 Ma ages from Dysart tonalite interpreted to record metamorphic zircon growth, and a ca. 1086 Ma Ottawan metamorphic age from a Dysart amphibolite. The ca. 1150–1100 Ma metamorphic event has not been previously documented within these thrust sheets of the CMBbtz, but correlates well with thermal events in the allochthonous Parry Sound domain to the west, as do ca. 1350 Ma igneous ages of tonalite in both areas. These data support the hypothesis that the CMBbtz and Parry Sound domain may have been initially linked. Widespread ca. 1350 Ma crust along with distinct 1460–1400 Ma depleted mantle model ages (T DM ) are also consistent with a shared genesis with the Dysart–Mount Holly suite in New York and Vermont, and support the correlation between the CMBbtz thrust sheets and the Adirondack Highlands–Mount Holly belt as a rifted arc. Alternatively, the CMBbtz thrust sheets and the Adirondack Highlands–Mount Holly belt may represent contemporaneous arc development at different parts of the convergent margin; however, we support the correlation between the CMBbtz thrust sheets and the Adirondack-Highlands–Mount Holly belt.
    Electronic ISSN: 1553-040X
    Topics: Geosciences
    Published by Geological Society of America (GSA)
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