ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A study of the transformation of Δ7-9, 11α-oxidosteroids into Δ8-11-ketosteroids leads to a new two-step process giving excellent yields. Thus Δ8-11-ketones of the ergostane, androstane and, for the first time, also of the cholestane series are prepared. Δ7-11-ketosteroids appear as intermediates which, according to their reactions, seem to belong to the 9β-series. On the basis of this observation a reaction mechanism for the isomerisation of epoxides into ketones is presented.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19530360209
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