ISSN:
1432-1041
Schlagwort(e):
Barium sulfate suspensions
;
gastrointestinal x-ray examinations
;
clinical trial
;
controlled
;
viscosity effects
;
osmolarity effects
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Chemie und Pharmazie
,
Medizin
Notizen:
Summary The quality of radiographs of the upper gastrointestinal tract is of great diagnostic importance, but the published reports about barium sulfate suspensions have been poorly controlled or limited to in vitro investigations. The present study consists of a double blind clinical trial comparing two commercially available barium sulfate suspensions, several additives and methods used to alter the viscosity of the suspension. The techniques employed include randomization, factorial design, application of predetermined criteria and computer analysis of the results. The results confirm the value of high viscosity suspensions for examining the oesophagus, but for the stomach and the intestines a lower viscosity appears adequate. Elevation of osmolarity accelerates intestinal transit but impairs double contrast and mucosal pictures. Some highly significant differences between the two barium preparations, e.g. in gastric peristalsis, cannot be accounted for. The analysis of results shows that improvement of present day techniques is desirable, but will depend on further results of properly controlled clinical trials.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00568897
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