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  • 1
    Electronic Resource
    Electronic Resource
    The pineal gland of the gerbil, Meriones unguiculatus (1979)
    Springer
    Cell & tissue research 204 (1979), S. 111-125 
    Details
    ISSN: 1432-0878
    Keywords: Pinealocytes ; Morphometric analysis ; Superior cervical ganglionectomy ; Fluorescence histochemistry ; Gerbil
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Morphometric analytical procedures were employed to study the pineal gland of the Mongolian gerbil following superior cervical ganglionectomy (SCGX). The purpose of this study was to define the effects of sympathetic denervation on the morphology of the gland at two time periods, 0500 and 1900 h (one hour before lights-on and lights-off, respectively). Fluorescence histochemistry was employed to determine catecholamine and indoleamine content in intact and denervated pineal glands. After SCGX, the pinealocytes decrease in size, concretions are prevented from forming, and the yellow fluorescence in the gland is lost. Following denervation a depression in the volume of most of the pinealocyte organelles, i.e., SER, RER/ribosomes, free cytoplasm, mitochondria and presumptive secretory vesicles, was also observed. However, synaptic ribbons increased in volume in the gerbils that had been killed at 1900 h. It appears that the sympathetic innervation to the pineal gland is a requirement for the presumptive secretory activity of the pinealocytes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00235168
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  • 2
    Electronic Resource
    Electronic Resource
    The pineal gland of the gerbil, Meriones unguiculatus (1979)
    Springer
    Cell & tissue research 204 (1979), S. 95-109 
    Details
    ISSN: 1432-0878
    Keywords: Pineal gland ; Gerbil ; Pinealocytes ; Morphometric analysis ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary By means of morphometric analytical procedures, a diurnal rhythm in the cellular volume of gerbil pinealocytes was determined. This rhythm has been attributed primarily to a change in the cytoplasmic volume of the pinealocytes which is low during the daylight hours and increases to reach a peak during the middle of the dark period. At the ultrastructural level, six cytoplasmic components of the pinealocytes were found to exhibit a rhythm: free cytoplasm, smooth endoplasmic reticulum (SER), rough endoplasmic reticulum (RER) and ribosomes, secretory vesicles, microtubules, and mitochondria. The presumptive secretory vesicles and the microtubules reached a peak in volume one hour before lights-off. It is suggested that lights-on and lights-off both signal a decrease in size and/or number of the secretory vesicles. The SER and RER/ribosomes reached their peak volume one hour after lights-off which is interpreted as indicating a peak in indoleamine synthesis and protein synthesis, respectively. The volume of free cytoplasm exhibits two peaks; one occurs one hour before lights-off while the second peak occurs in the middle of the dark phase. It is suggested that, although part of the secretory product of the pinealocyte may be present in dense-cored vesicles, other locations could include the free cytoplasm and clear secretory vesicles.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00235167
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  • 3
    Electronic Resource
    Electronic Resource
    Ultrastructure of pinealocytes of the cotton rat, Sigmodon hispidus (1979)
    Springer
    Cell & tissue research 204 (1979), S. 407-416 
    Details
    ISSN: 1432-0878
    Keywords: Pineal gland ; Ultrastructure ; Cotton rat (Sigmodon hispidus)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Fine structural features of pinealocytes of cotton rats (Sigmodon hispidus) were examined. Golgi complexes, mitochondria, endoplasmic reticulum and polysomes are usual organelles seen in the perikaryonal cytoplasm of pinealocytes. Many non-granulated vesicles (40 to 80 nm in diameter) and a few granulated vesicles (about 100 nm in diameter) are associated with the Golgi cisternae. Occasionally, the cisternae contain granular materials. The perikaryonal cytoplasm of pinealocytes is characterized by the presence of inclusion bodies. These bodies are usually round in shape, not bounded by a limiting membrane and composed of fine granular or filamentous materials of high electron-opacity, which are similar in appearance to the substance seen in the nucleolonema. Pinealocyte processes, filled with abundant non-granulated vesicles and some granulated vesicles, are mainly found within the parenchyma and occasionally in perivascular spaces.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00233652
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  • 4
    Electronic Resource
    Electronic Resource
    The pineal gland of the gerbil, Meriones unguiculatus (1978)
    Springer
    Cell & tissue research 193 (1978), S. 323-336 
    Details
    ISSN: 1432-0878
    Keywords: Pineal gland ; Gerbil ; Pinealocytes ; Concretions ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Electron microscopy was employed in a study of the pineal gland of the Mongolian gerbil (Meriones unguiculatus). It was determined that the gerbil pineal gland contains pinealocytes and glial cells with the pinealocytes being the predominant cell type. The pinealocytes contain numerous organelles traditionally considered as being either synthetic or secretory in function such as an extensive Golgi region, smooth (SER) and rough (RER) endoplasmic reticulum, secretory vesicles and microtubules. Other cytoplasmic components are also present in the pinealocytes (synaptic ribbons, subsurface cisternae) for which no function has been assigned. Dense-cored vesicles are rare. Vacuolated pinealocytes are present and appear to be intimately associated with the formation of the pineal concertions. Evidence presented supports the proposal that the concretions form within the vacuoles. Once the concretions reach an enlarged state, the vacuolated pinealocytes break down and the concretions are thus extruded into the extracellular space where they apparently continue to increase in size. The morphology of the glial cells was interpreted as indicative of a high synthetic activity. The glial cells contain predominantly the rough variety of endoplasmic reticulum and form an expansion around the wide perivascular area.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00209044
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  • 5
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    The pineal gland of the gerbil, Meriones unguiculatus (1979)
    Springer
    Details
    Publication Date: 1979-12-01
    Print ISSN: 0302-766X
    Electronic ISSN: 1432-0878
    Topics: Biology , Medicine
    Published by Springer
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  • 6
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    The pineal gland of the gerbil, Meriones unguiculatus (1979)
    Springer
    Details
    Publication Date: 1979-12-01
    Print ISSN: 0302-766X
    Electronic ISSN: 1432-0878
    Topics: Biology , Medicine
    Published by Springer
    Location Call Number Expected Availability
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    PAPER CURRENT
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