Publication Date:
1979-06-08
Description:
Thirteen of 31 rabbits immunized repeatedly with bovine brain galactocerebroside developed experimental allergic neuritis, manifested by flaccid paresis and hypesthesia of four limbs, 2 to 11 months after the initial inoculation. Electrophysiological studies revealed multifocal conduction block of peripheral nerves. Perivenular demyelinative lesions associated with phagocytic mononuclear cells occurred in spinal ganglia, roots, and less frequently in distal nerves.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Saida, T -- Saida, K -- Dorfman, S H -- Silberberg, D H -- Sumner, A J -- Manning, M C -- Lisak, R P -- Brown, M J -- New York, N.Y. -- Science. 1979 Jun 8;204(4397):1103-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451555" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Autoantibodies/analysis
;
Autoimmune Diseases/*immunology
;
Cerebrosides/*immunology
;
Demyelinating Diseases/*immunology/pathology
;
Galactosylceramides/*immunology
;
Male
;
Myelin Sheath/physiopathology
;
Neural Conduction
;
Neuritis/*immunology/pathology/physiopathology
;
Rabbits
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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