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  • 1
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    The stomach signals satiety (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-07-14
    Description: Inflatable pyloric cuffs and stomach tubes were implanted in rats. With the cuff inflated and a valve to limit intragastric pressure to that accompanying normal satiety, they drank only as much when they had been deprived of food for 12 hours as without inflation of the cuff. However, they overdrank with the cuff inflated when they had been water deprived for 12 hours. When 10 ml of milk was withdrawn from the stomach with the cuff inflated, compensatory drinking occurred. Further, compensatory drinking also occurred when milk escaped from the stomach into the duodenum. Satiety signals thus arise from the stomach.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Deutsch, J A -- Young, W G -- Kalogeris, T J -- New York, N.Y. -- Science. 1978 Jul 14;201(4351):165-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/663647" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Drinking Behavior/physiology ; Duodenum/physiology ; Food Deprivation ; Male ; Rats ; Satiation/*physiology ; Satiety Response/*physiology ; Stomach/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Feeding and behavioral activation in infant rats (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-13
    Description: Three-day-old rats that were separated from their mothers and deprived of food were found to be capable of feeding either from small puddles of milk or when milk was infused into the front of their mouths. Such feeding was accompanied by a dramatic increase in behavioral activity and only occurred in a warm environment. These data demonstrate that neural systems for ingestive behavior are present at birth and suggest the existence of feeding-related arousal or motivational systems.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hall, W G -- New York, N.Y. -- Science. 1979 Jul 13;205(4402):206-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451591" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Animals, Newborn/*physiology ; Behavior, Animal/*physiology ; Feeding Behavior/*physiology ; Food Deprivation ; Movement ; Rats ; Temperature ; Time Factors
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Appetitive learning in 1-day-old rat pups (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-27
    Description: One-day-old rat pups learned to probe upward into a terry-cloth-covered paddle when they were rewarded with small infusions of milk into their mouths. In the presence of two paddles, discriminable on the basis of odor and position in the test container, the pups learned to probe into the paddle that provided them with milk. These experiments demonstrate (i) that milk may serve as a reinforcer to deprived rat pups and (ii) that pups as young as 1 day are capable of appetitive learning.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Johanson, I B -- Hall, W G -- New York, N.Y. -- Science. 1979 Jul 27;205(4404):419-21.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451612" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Animals, Newborn ; *Feeding Behavior ; Food Deprivation ; *Learning ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Chronic focal epileptiform discharges induced by injection of iron into rat and cat cortex (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-06-30
    Description: A single injection of 5 or 10 microliters of ferrous or ferric chloride into rat or cat sensorimotor cortex resulted in chronic recurrent focal paroxysmal electroencephalographic discharges as well as behavioral convulsions and electrical seizures. Recurrent focal epileptiform discharge caused by cortical injection of iron salts suggests that the development of human posttraumatic epilepsy may depend, in part, on the neurochemical alterations induced by the principal metallic ions found in whole blood.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Willmore, L J -- Sypert, G W -- Munson, J V -- Hurd, R W -- New York, N.Y. -- Science. 1978 Jun 30;200(4349):1501-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/96527" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cats ; Cerebral Cortex/*drug effects/physiopathology ; *Disease Models, Animal ; Electrophysiology ; Epilepsies, Partial/*chemically induced ; Ferric Compounds ; Ferrous Compounds ; *Iron ; Rats ; Seizures/*chemically induced/physiopathology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Polarity of the blood-brain barrier: neutral amino acid transport into isolated brain capillaries (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-10-13
    Description: Capillary endothelial cells isolated from rat brain exhibit Na+-dependent uptake of the neutral amino acid analog alpha-(methylamino)isobutyric acid. Since studies in vivo demonstrate that this transport system is not present on the blood side of brain capillaries we conclude that Na+-dependent neutral amino acid transport is located on the brain side. Therefore, the luminal plasma membrane and the antiluminal plasma membrane appear to be functionally distinct. This polarity should permit brain capillary endothelial cells to actively regulate the internal milieu of the brain.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Betz, A L -- Goldstein, G W -- New York, N.Y. -- Science. 1978 Oct 13;202(4364):225-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/211586" target="_blank"〉PubMed〈/a〉
    Keywords: Aminoisobutyric Acids/*analogs & derivatives/metabolism ; Animals ; Biological Transport, Active ; *Blood-Brain Barrier ; *Capillary Permeability ; Cell Membrane/metabolism/ultrastructure ; Cerebral Cortex/*blood supply ; Endothelium/metabolism ; In Vitro Techniques ; Leucine/*metabolism ; Rats ; Sodium/metabolism ; Sodium-Potassium-Exchanging ATPase/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Chronic zinc deficiency alters neuronal function of hippocampal mossy fibers (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-07
    Description: Low-frequency stimulation of hippocampal mossy fiber axons in zinc-deficient adult rats produced synaptic responses that declined in amplitude with successive stimuli. This response decrement is abnormal and suggests that the heavy deposits of zinc in mossy fiber boutons are important for synaptic transmission.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hesse, G W -- New York, N.Y. -- Science. 1979 Sep 7;205(4410):1005-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/224456" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Evoked Potentials ; Hippocampus/*physiology ; Male ; Rats ; Synapses/physiology ; Synaptic Transmission ; Zinc/*deficiency
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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