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  • 21
    Electronic Resource
    Electronic Resource
    Human interferon production with diploid fibroblast cells grown on microcarriers (1979)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 21 (1979), S. 433-442 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A variety of diploid human fibroblast lines have been successfully grown to high densities (〉106 cell/ml) on recently developed microcarriers. Interferon induction using poly I·poly C and a superinduction procedure resulted in yields greater than 10,000 units/ml with one cell line. A direct comparison of microcarrier cultures to roller bottle cultures showed equivalent interferon yields on a per cell basis and some apparent differences relating to optimum inducer concentrations and kinetics of interferon accumulation.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260210306
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  • 22
    Electronic Resource
    Electronic Resource
    Enzyme immobilization on fibrin (1976)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 18 (1976), S. 133-139 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 5 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260180112
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  • 23
    Electronic Resource
    Electronic Resource
    Preliminary cost estimates for commercial fermentation of straw as animal feedContribution of the Agricultural Experiment Station, Technical Paper No. 4385, Oregon State University, in cooperation with the Agricultural Research Service, U.S. Department of Agriculture. (1977)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 19 (1977), S. 1817-1830 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A preliminary cost estimate was made for two fermentation processes that increase the feed value of grass straw. In one method, straw hydrolyzed with dilute sulfuric acid is fermented by yeast. In the second method, the straw is treated with alkali, then inoculated with cellulolytic bacteria. Both processes increase the digestibility, protein content, and fat content of straw. Production costs estimated for plants processing 100 tons of straw/day by the two methods, were 80 to 88 dollars/ton. Capital costs were estimated at 5.2 million dollars for the acidhydrolysis yeast-fermentation process and at 3.1 million dollars for the alkalicellulolytic bacteria process. Labor, capital, and energy were significant cost factors for both processes. Caustic costs were important in the alkaline-treatment cellulolytic bacteria process.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260191207
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  • 24
    Electronic Resource
    Electronic Resource
    The tubular loop fermentor: Oxygen transfer, growth kinetics and design (1977)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 19 (1977), S. 507-525 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Oxygen transfer measurements using a dynamic method and evaluated with an appropriate mathematical model have been made on a tubular loop bioreactor. Correlations of the type used in tank systems are used to describe the influence of power and aeration rate on the mass transfer coefficient. Yeast cultures grown on hydrocarbon and glucose substrates show growth characteristics similar to conventional tank results. Model considerations for large-scale tubular fermentors allow for the prediction of the steady-state oxygen profiles and maximum reactor length. Combination with two-phase flow and oxygen transfer correlations yields a design procedure for commercial scale tubular loop fermentors.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260190406
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  • 25
    Electronic Resource
    Electronic Resource
    Mutation to increased resistance to phenol in Pseudomonas putida (1978)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 20 (1978), S. 917-920 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260200612
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  • 26
    Electronic Resource
    Electronic Resource
    Influence of manufacturing variables on the characteristics and effectiveness of chitosan products. I. Chemical composition, viscosity, and molecular-weight distribution of chitosan products (1978)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 20 (1978), S. 1931-1943 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Ten chitosan products were manufactured from dry shrimp hulls under differing process conditions and compared to a commercially available product. Manufacturing variables tested were: alkali versus enzymatic deproteination; acid demineralization versus no treatment; air versus nitrogen atmosphere; 5 min vs. 15 min deacetylation period: and varying the particle size of the dry starting material. Deproteination by alkali of enzymatic extraction did not substantially affect the nitrogen and ash compositions of dry chitosan samples. However, the viscosity was reduced in samples deproteinated by enzymatic hydrolysis. Elimination of the demineralization step resulted in products having 31-36% ash, as expected. Some differences in viscosity were observed between deminiralized and undemineralized samples, but on important differences in the molecular-weight distribution of these samples were evident. Purging the reaction vessel with nitrogen resulted in chitosan preparations having higher viscosities and molecular-weight distributions than those prepared in an air atmosphere. The degradative effect of air became more proshrimp hulls to 1 mm prior to any treatment resulted in a chitosan product of both higher viscosity and molecular weight than when ground to either 2 or 6.4 mm. Viscosity was not always a direct indicator of molecular weight, for although the presence of colloidal particles increased the viscosity of some samples, the molecular-weight distribution after filtration was essentially the same as in other less viscous samples.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260201208
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  • 27
    Electronic Resource
    Electronic Resource
    Cell concentration control by viscosity (1976)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 18 (1976), S. 1793-1805 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The apparent viscosity of baker's yeast suspensions was employed to control the cell concentration of the mixing of baker's yeast and distilled water. The apparent viscosity of baker's yeast was found to be a function of cell concentration and independent of the flow rate through the rotational viscometer. The viscometer and mixing unit were found to have first order dynamics. The open loop dynamics of the control system were nonlinear but could be linearized for small perturbations. The control system was employed to successfully control the cell concentration but exhibited nonlinear behavior.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260181212
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  • 28
    Electronic Resource
    Electronic Resource
    Process for the aerobic conversion of poultry manure into high-protein feedstuffThis paper was given, in part, at a NSF-RANN Grantees-Users Conference on Non-Conventional Protein and Foods, October 18-29, 1977, at the University of Wisconsin. (1979)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 21 (1979), S. 19-38 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A two-stage aerobic continuous process is suggested for the conversion of poultry waste into a single-cell protein (SCP) product. The technical feasibility of the process is examined in this paper. Using bench-scale apparatus the approximate growth kinetics have been discovered. Possible modes of product recovery have been examined. The product consists primarily of a strain of Pseudomonas fluorescens which has a lysine-rich (∼9.3%) amino acid profile that could make this product an attractive feed ingredient for poultry diets.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260210103
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  • 29
    Electronic Resource
    Electronic Resource
    Materials Science and its Levels of Development (1977)
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 8 (1977), S. 289-294 
    Details
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Zum gegenwärtigen Stand der WerkstoffwissenschaftenWerkstoffwissenschaften als neue Philosophie.Was bedeutet der Begriff Werkstoffwissenschaften?Gründe zur Einführung von Kursen in Australien und den USA und Beschreibung des Lehrangebots für Studenten der Ingenieur- und verwandter Wissenschaften. Bedeutung der Werkstoffwissenschaften in anderen Ländern. Ist der Begriff „Werkstoffwissenschaften“, der mit der Studienreform in Deutschland an einigen Universitäten und Technischen Hochschulen eingeführt wurde, gleichbedeutend mit dem Begriff „Materials Science“?Beschreibung von Lehrveranstaltungen in Australien und den USA.
    Notes: Materials Science as a new philosophy. What is Materials Science? Prerequisites for its introduction. Reasons for creating courses in Australia and the U.S.A. and description of its teaching as a servicing subject to students of engineering and related sciences (lower level) and as an individual subject (upper level). The success of Materials Science in other countries. Is Werkstoffwissenschaften, the term given after the Studienreform to some of the new Fachbereiche replacing the former Faculties at many Technical Universities in the former Faculties at many Technical Universities in the Federal Republic of Germany, the same as Materials Science? Description of Materials Science courses in Australia and the U.S.A.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mawe.19770080903
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  • 30
    Electronic Resource
    Electronic Resource
    Untersuchungen an stahlfaserverstärktem Aluminium unter Torsions- und Druckbeanspruchungen (1978)
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 9 (1978), S. 27-30 
    Details
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Investigation of Steel Fiber Reinforced Aluminium under Torsional and Compressive LoadingA fiber-shaped composite material which, due to its fabrication process and internal structure may be called a double fiber composite, and whose strength behaviour is significantly influenced by boundary layers and porosity has been tested by means of two test methods: 1The possibility is demonstrated to determine by a non-destructive elastic torsional test the useful cross section for the utilization of the material, taking the quality-reducing factors into consideration.2Pressure tests have shown good agreement with Timoshenko and Gere's wave theory extended in this particular case. .
    Notes: Die Erprobung eines faserförmigen Verbundwerkstoffes, der durch Herstellungsverfahren und inneren Aufbau als Doppelfaserverbund zu bezeichnen ist und dessen Festigkeitsverhalten durch Grenzschichten und Porosität wesentlich beeinflußt wird, wurde mittels zweier Prüfverfahren durchgeführt: 1Es wird die Möglichkeit aufgezeigt, den nutzbaren Querschnitt für den Einsatz des Materials unter Berücksichtigung der qualitätsmindernden Faktoren im elastischen Torsionsversuch zerstörungsfrei zu ermitteln.2Durch Druckversuche wurde eine gute Übereinstimmung mit der hier erweiterten Wellentheorie von Timoshenko und Gere erzielt. .
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mawe.19780090109
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