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  • 1
    Electronic Resource
    Electronic Resource
    Fine structure of the gills of some Indian air-breathing fishes (1979)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 160 (1979), S. 169-193 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: A detailed account is given of the structure of the gills of Clarias batrachus, Heteropneustes (= Saccobranchus) fossilis, Channa punctata, Monopterus (= Amphipnous) cuchia and Boleophthalmus boddaerti, based upon light and electron microscopy. In all five species the basic organization into primary and secondary lamellae is apparent but the latter are very much more modified in Monopterus.Three main layers separate the water and blood on the surface of the secondary lamellae. The outer epithelium is usually two layered but may be multilayered close to the origin of the secondary lamellae from the gill filament. The basement membrane is relatively thin and a middle dense layer containing collagen fibrils separates two clear layers. The pillar cells, so characteristic of secondary lamellae, are present in all except Monopterus and flanges from these cells surround the blood channels with the exception of the marginal channels. The latter are lined by endothelial cells which line all the blood channels of Monopterus.The overall thickness of the three layers comprising the water/blood barrier ranges from 1.5 to 13 microns. A number of modifications to this basic organization can be related to the degree of dependence of the different species on air-breathing.Boleophthalmus is the only species commonly found in brackish water and its secondary lamellae have well developed lymphoid spaces between two layers of the epithelium. Special densely-stained regions of the pillar cell flanges were also present in this fish and may have a supporting function.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051600205
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Immunological characterization of hypoxanthine-guanine phosphoribosyl transferase mutants of mouse L cells: Evidence for mutations at different loci in the HGPRT gene (1975)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 85 (1975), S. 307-320 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: A large collection (105) of mouse L cell mutants lacking hypoxanthine-guanine phosphoribosyl transferase activity (HGPRT; E. C. 2.4.2.8) were analyzed for the presence of serologically cross reacting material (CRM). Antibody directed against highly purified mouse liver HGPRT was used for detecting CRM activity by two methods: (1) the standard precipitation-inhibition assay; and (2) a radioimmune-precipitation assay. The latter assay proved to have far greater sensitivity for the detection of altered forms of HGPRT. Approximately 40% of the HGPRT- cell lines contain CRM activity (i.e., were CRM+). This indicates that a minimum of 40% of the HGPRT- clones arose as a result of mutations in the HGPRT structural gene. The CRM+ cell lines were shown to contain different levels of CRM activity. Measurements of the heat sensitivity of CRM in the different HGPRT- cell lines showed a broad spectrum of CRM heat inactivation kinetics. These latter two observations provide strong evidence that the mutations giving rise to the HGPRT-CRM+ phenotype occurred at different sites in the HGPRT structural gene.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1040850217
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  • 3
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    Tissue perfusion rate determined from the decay of oxygen-15 activity after photon activation in situ (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-15
    Description: Rates of cerebral perfusion were obtained from measurements of the disappearance (wash-out) of oxygen-15 after in situ tissue activation with 45-million-volt x-rays. In an anesthetized cat, typical values were 90 milliliters per minute per 100 grams of tissue, with 55 percent wash-out. In a specific radiotherapy patient, the value was 65 milliliters per minute per 100 grams of tissue, with 63 percent wash-out of oxygen-15 through incorporation into tissue water.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hughes, W L -- Nussbaum, G H -- Connolly, R -- Emami, B -- Reilly, P -- New York, N.Y. -- Science. 1979 Jun 15;204(4398):1215-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451567" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Brain/*blood supply ; Cats ; Humans ; Neoplasms/blood supply ; Oxygen/*blood/radiation effects ; Oxygen Radioisotopes ; *Regional Blood Flow ; X-Rays
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Enkephalin-like material elevated in ventricular cerebrospinal fluid of pain patients after analgetic focal stimulation (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-08-04
    Description: Enkephalin-like activity has been measured in the ventricular cerebrospinal fluid of patients with intractable pain. Electrical stimulation of periventricular brain sites resulted in significant decrease in persistent pain in these subjects. This analgesia, which was blocked by naloxone in 80% of the cases, was accompanied by a significant rise in ventricular enkephalin-like activity, as measured by two different methods. The results present evidence of in vivo release of enkephalin-like material in humans and suggest that stimulation analgesia may be partially due to this release.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Akil, H -- Richardson, D E -- Hughes, J -- Barchas, J D -- New York, N.Y. -- Science. 1978 Aug 4;201(4354):463-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/663668" target="_blank"〉PubMed〈/a〉
    Keywords: Brain/*physiopathology ; Cerebral Aqueduct ; Electric Stimulation ; Endorphins/*cerebrospinal fluid ; Enkephalins/*cerebrospinal fluid ; Female ; Humans ; Male ; Pain/*cerebrospinal fluid/physiopathology ; Pain Management
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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