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  • Glial cells  (1)
  • Optimal control  (1)
  • Springer  (2)
  • American Association for the Advancement of Science
  • American Physical Society (APS)
  • Periodicals Archive Online (PAO)
  • 1975-1979  (2)
Collection
Publisher
  • Springer  (2)
  • American Association for the Advancement of Science
  • American Physical Society (APS)
  • Periodicals Archive Online (PAO)
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Year
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 199 (1979), S. 519-528 
    ISSN: 1432-0878
    Keywords: Filum terminale ; Spinal cord ; Glial cells ; Ultrastructure ; Frog (Rana pipiens)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The filum terminale, or terminal portion of the spinal cord, was studied in normal adult frogs (Rana pipiens) by means of light and electron microscopy. Astroglial cells are the predominant elements in this region. The rostral portion of the filum terminale consists mainly of (1) a peripheral dense ring of myelinated and some unmyelinated nerve fibers, and processes of astrocytes terminating at the subpial space; (2) an intermediate zone, in which astrocytes are the main cellular elements in addition to a few degenerated neurons; and (3) a central region where the central canal is lined by dark and light ependymal cells. In the caudal portion of the filum terminale, the amount of neuropil is greatly reduced. This region is formed mainly by astrocytic glial cells and very few neuronal elements. The central canal in the caudal portion is located ventrally and contains a lining consisting almost exclusively of dark ependymal cells.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of optimization theory and applications 26 (1978), S. 395-425 
    ISSN: 1573-2878
    Keywords: Optimal control ; numerical methods ; computing methods ; gradient methods ; gradient-restoration algorithms ; sequential gradient-restoration algorithms ; general boundary conditions ; nondifferential constraints ; bounded control ; bounded state
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract This paper considers the numerical solution of two classes of optimal control problems, called Problem P1 and Problem P2 for easy identification. Problem P1 involves a functionalI subject to differential constraints and general boundary conditions. It consists of finding the statex(t), the controlu(t), and the parameter π so that the functionalI is minimized, while the constraints and the boundary conditions are satisfied to a predetermined accuracy. Problem P2 extends Problem P1 to include nondifferential constraints to be satisfied everywhere along the interval of integration. Algorithms are developed for both Problem P1 and Problem P2. The approach taken is a sequence of two-phase cycles, composed of a gradient phase and a restoration phase. The gradient phase involves one iteration and is designed to decrease the value of the functional, while the constraints are satisfied to first order. The restoration phase involves one or more iterations and is designed to force constraint satisfaction to a predetermined accuracy, while the norm squared of the variations of the control, the parameter, and the missing components of the initial state is minimized. The principal property of both algorithms is that they produce a sequence of feasible suboptimal solutions: the functions obtained at the end of each cycle satisfy the constraints to a predetermined accuracy. Therefore, the values of the functionalI corresponding to any two elements of the sequence are comparable. The stepsize of the gradient phase is determined by a one-dimensional search on the augmented functionalJ, while the stepsize of the restoration phase is obtained by a one-dimensional search on the constraint errorP. The gradient stepsize and the restoration stepsize are chosen so that the restoration phase preserves the descent property of the gradient phase. Therefore, the value of the functionalI at the end of any complete gradient-restoration cycle is smaller than the value of the same functional at the beginning of that cycle. The algorithms presented here differ from those of Refs. 1 and 2, in that it is not required that the state vector be given at the initial point. Instead, the initial conditions can be absolutely general. In analogy with Refs. 1 and 2, the present algorithms are capable of handling general final conditions; therefore, they are suited for the solution of optimal control problems with general boundary conditions. Their importance lies in the fact that many optimal control problems involve initial conditions of the type considered here. Six numerical examples are presented in order to illustrate the performance of the algorithms associated with Problem P1 and Problem P2. The numerical results show the feasibility as well as the convergence characteristics of these algorithms.
    Type of Medium: Electronic Resource
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