ISSN:
1432-1041
Keywords:
Antiarrhythmic drug
;
propafenone
;
serum concentration
;
atrioventricular conduction time
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary Seven patients with cardiac dysrhythmias received a single, oral, therapeutically effective dose of the antiarrhythmic drug propafenone. The serum levels correlated well with changes in atrioventricular conduction times during the postabsorptive elimination phase (r=0.6810, p〈0.001). The mean half-lives of the serum level and the electrocardiographic effect (PQ-time) were 3.6±0.2 h and 3.8±0.6 h, respectively.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00606676
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