Publication Date:
1979-08-24
Description:
Intraperitoneal injection of monosodium glutamate in neonatal rates resulted in a 90 percent loss of alpha-melanocyte-stimulating hormone in hypothalamic and extrahypothalamic areas of the brain, whereas the amount of hormone in the pituitary gland did not change. The dramatic reduction of alpha-melanocyte-stimulating hormone in the brain suggests that is primary source there is the neuronal perikarya of the arcuate nucleus.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Eskay, R L -- Brownstein, M J -- Long, R T -- New York, N.Y. -- Science. 1979 Aug 24;205(4408):827-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/462194" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
*Animals, Newborn
;
Brain/*metabolism
;
Glutamates/*pharmacology
;
Melanocyte-Stimulating Hormones/*metabolism
;
Rats
;
Sodium Glutamate/*pharmacology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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