ALBERT

Notes: A family with examples of the rare condition known as ‘inherited mosaicism affecting the ABO blood groups’ has been studied. In this family there were five examples of Bmos:O mosaicism. Blood group gene-specified transferase estimations were studied in this condition for the first time. In ‘affected' members, levels of B gene-specified transferease were low, and amounted to only 7-10% of the activity of a normal control. It is proposed that Bmos is correctly classified as a new form of weak B.

Notes: Cad, Sd(a++) or Super Sda is a rare, inherited, dominant blood group character which is of much interest, not only with regard to problems in pretransfusion tests (erythrocyte polyagglutination) but also in the field of lectin specificity. We have studied this blood group character in a British family with Eastern connections and present a brief account of its serological and clinical importance. Most persons are Sd(a+) but there is a wide distribution of antigen strength, ranging from ordinary Sd(a+) to Cad. Most persons also have weak anti-Sda in their serum; this is ordinarily of no clinical importance, but could cause problems if Cad bloods are transfused. The chief structural determinant of Cad specificity is N-acetyl-d-galactosamine in α-linked position, yet it is clearly distinguishable by use of appropriate lectins from other blood group antigens, A and Tn, which also have this acetyl-hexosamine as their chief structural determinant. A method for the rapid identification of Cad, applicable to all ABO groups, is described. The lectin of Dolichos biflorus, which is specific for N-acetyl-d-galactosamine in α-linked position, reacts strongly with A(A1), Tn and Cad cells, its action on Cad cells being much the strongest. Absorption-elution studies show that one and the same lectin reacts with both A1 and Tn cells. Absorption with Cad cells abolishes activity for A1, Tn and Cad cells; whereas absorption with A1 or Tn cells leaves activity for Cad. This does not necessarily indicate that anti-Cad is a separate component since the same result can be obtained by simply diluting the Dolichos reagent. However, eluates from Cad cells react only with Cad cells, whereas eluates from A1 or Tn cells react with A1, Tn and Cad cells.

Notes: The low resolution and complete high resolution mass spectra of a series of methyl and deuterium substituted bicyclo[4.1.0]heptane-2-one derivatives have been measured. An attempt has been made to test the operation of a fragmentation process analogous to the known photochemical rearrangement, and to determine if the substitution effects critical to the photorearrangement also influence the electron-impact process. The fragmentation pattern of these conjugated cyclopropyl ketones is detailed and the influence of the cyclopropyl ring is discussed. It is suggested that electron-impact-induced rearrangements which are analogous to photochemical transformations will be relatively low energy processes and will remain prominent at low ionizing voltages.

Notes: Observation wells and access holes for neutron probe use were drilled by a jet-percussion drill rig in coarse alluvial material near Tucson, Arizona. The method combines the jetting action which effectively removes loose materials with the percussion necessary to break up tighter formations and large particles. A unique feature of the equipment is the provision for simultaneous drilling and driving the casing to keep the hole open in loose formations. Washed samples of the material being drilled can be obtained from the recirculating water system. Drilling rates were from seven to ten feet per hour, and costs including casing were less than $1.50 per foot. Maximum depth is about 100 feet.Hydrologic study of a ground-water reservoir requires access to the aquifer. Observations are made where the water table intersects the land surface, such as at springs or seeps, or through existing wells. However, wells are not always found in desired locations or are pumped so heavily that their usefulness as observation wells is impaired. Measurements are also made in the unsaturated zone with neutron moisture measuring equipment, which requires a small diameter cased access hole for the neutron probe.An observation well needs a diameter only large enough for access by measuring devices and must be immediately responsive to changes in aquifer water level. For neutron probe use, the required diameter is about two inches, and the well must have no significant effect on moisture movement in the unsaturated zone. To meet these requirements the drilling process should have no lasting effect on the formation surrounding the well. Finally, since the wells have no economic utility, construction cost must be low.A network of observation wells and neutron probe access holes was drilled as part of a project to evaluate the natural recharge from Rillito Creek near Tucson, Arizona. The formation along the creek bed is a coarse alluvial outwash containing almost no clay, considerable running sand, and some large gravel and boulders. Commercial churn (percussion) and hydraulic rotary drills, commonly used for drilling in this area, were first tried but encountered much difficulty in the loose materials.Previous investigators used jetting equipment drill small diameter holes in a variety of alluvi formations (Cederstrom and Tibbitts, 1961; Bowma: 1911; and Pillsbury and Christiansen, 1947). Howeve in most cases, either open hole drilling was used because the fine material content and the limited numb. of boulders or large gravel particles made this methc possible, or drilling mud was used to maintain th hole. The jetting method uses water pumped unde pressure through hollow rods and a drill bit to loose the material and carry it to the surface. The jettin water receives little aid from the drill in loosenin the material to be removed. Usually the drill cutting are settled out in a tank or basin, and the water i recirculated.

Notes: : When a series of aerators are used to raise the level of dissolved oxygen in a polluted stream through instream artificial aeration augmentation, the system is governed by the basic dissolved oxygen mass balance equation with the existence of artificial aeration as its boundary conditions. A mathematical model is formulated for the optimization of the allocation of aeration capacity to each of the series of aerators subject to a limitation on total available aeration capacity. The objective function is the minimization of the sum of the squares of the aeration costs and the costs incurred by damaging or unnecessarily improving the system. The original constrained allocation problem is simplified by converting it to an unconstrained one via the use of Lagrange multiplier. A discretized dynamic programming algorithm is formulated for finding the optimal allocation policy. A typical optimal aeration capacity allocation policy and its corresponding dissolved oxygen sag profile for the illustrated numerical example is presented, and the relationship between the total available aeration capacity and Lagrange multiplier is also developed treating weighting factors as parameters.