ISSN:
0021-9304
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
,
Technology
Notes:
The adsorption of radiotagged fibrinogen on modified polytetrafluoroethylene surfaces was measured to shed light on the reason of reduced thrombogenicity. These measurements show that when fibrinogen is adsorbed from a solution in which the molecules are in a coiled, undenatured state, adsorption is greater on sulfonated, etched Teflon - a reduced thrombogenic surface, than on unsulfonated, etched Teflon - a thrombogenic surface. On the other hand, when fibrinogen is picked up from a water-air interface in the form of a monolayer consisting of denatured molecules, the pick-up is independent of the thrombogenicity of the surface.
Additional Material:
2 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jbm.820040206
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