Publication Date:
1983-07-22
Description:
The intracellular pH (pH(i))of encysted gastrula-stage embryos of the brine shrip, Artemia, as previously shown by in vivo phosphorus-31 nuclear magnetic resonance spectroscopy, increases by more than 1 unit during arousal from cryptobiotic dormancy and decreases by the same amount during reinduction of dormancy. These changes in pH(i) are now shown to be a fundamental regulator of the transitions between dormancy and metabolism: acidification of activated embryo pH(i) by more than 1 unit with carbon dioxide induced a state comparable to natural dormancy, while alkalinization of dormant embryo pH(i) with the weak base ammonia terminated natural dormancy. This demonstration of pH(i)-mediated regulation of cryptobiotic dormancy extends the known scope for pH(i) as a regulator of development to include multicellular stages of the metazoan life cycle.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Busa, W B -- Crowe, J H -- New York, N.Y. -- Science. 1983 Jul 22;221(4608):366-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17798891" target="_blank"〉PubMed〈/a〉
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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