Electronic Resource
Springer
Molecular genetics and genomics
190 (1983), S. 227-232
ISSN:
1617-4623
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary UV damage in a repair-deficient strain has been repaired when a repair-proficient strain has joined it in a heterokaryon. By substituting various repair-deficient mutants for the two components of this system, it has been shown that the rescue is accomplished by means of the excision repair system for pyrimidine dimers. Mutation has been monitored in the rescued nuclei and found to occur with a low frequency. When the rescuing component is replaced by a strain which lacks the excision repair system, there is a low frequency of rescue and the rescued nuclei have a high incidence of mutation. It is concluded that excision repair is relatively mutation-free, but in its absence another repair system is called upon which produces mutations.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00330644
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