Publication Date:
1982-06-25
Description:
The concentrations of oxytocin, arginine vasopressin, and estrogen stimulated neurophysin in cerebrospinal fluid of monkeys showed a daily fluctuation with high concentrations occurring during the light period. The patterns of oxytocin and estrogen-stimulated neurophysin in the cerebrospinal fluid were not observed in the plasma nor were they altered after the administration of a dose of estradiol that increased concentrations of estrogen-stimulated neurophysin in plasma. The disassociation between these cerebrospinal fluid and plasma patterns and values suggests that the secretory activity of neurons that release estrogen-stimulated neurophysin and oxytocin into the cerebrospinal fluid is controlled by mechanisms different from those that control their release into the plasma.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Perlow, M J -- Reppert, S M -- Artman, H A -- Fisher, D A -- Self, S M -- Robinson, A G -- New York, N.Y. -- Science. 1982 Jun 25;216(4553):1416-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7201163" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Arginine Vasopressin/blood/*cerebrospinal fluid
;
Circadian Rhythm
;
Estradiol/pharmacology
;
Macaca mulatta
;
Male
;
Neurons, Efferent/secretion
;
Neurophysins/*cerebrospinal fluid
;
Oxytocin/blood/*cerebrospinal fluid
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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