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  • AERODYNAMICS  (420)
  • Cell & Developmental Biology  (372)
  • Fluid Mechanics and Thermodynamics
  • 1980-1984  (702)
  • 1940-1944  (58)
  • 1930-1934  (33)
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  • 1
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: In this study, the intracellular concentrations of six elements (mmole/kg dry weight) were directly measured in the muscle fibers of pectoralis major muscles of eight week old, genetically dystrophic and normal chickens by the X-ray microanalysis technique. The extent of muscle degeneration was evaluated by morphometric measurements of muscle fiber diameter and other histological changes. A significant increase in the concentration of intracellular sodium and chlorine was evident in dystrophic muscles. The concentration of intracellular sodium was 127.0 ± 35.0 in the muscle fibers of dystrophic chicks compared to 65.7 ± 16.5 in normal controls. The concentration of chlorine was 90.5 ± 27.5 and 54.1 ± 5.5 in the muscle fibers of dystrophic and normal chicks respectively. The intracellular concentrations of potassium, magnesium, phosphorous, and sulfur remained unchanged in the dystrophic condition. Morphometric studies revealed that the dystrophic pectoralis muscles contain fewer but thicker fibers per unit area compared to normal pectoralis muscles. The importance of these findings are discussed in relation to the results of earlier investigations.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 112 (1982), S. 307-315 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The Ca2+ activation mechanism of the longitudinal body wall muscles of Parastichopus californicus (sea cucumber) was studied using skinned muscle fiber bundles. Reversible phosphorylation of the myosin light chains correlated with Ca2+-activated tension and relaxation. Pretreatment of the skinned fibers with ATPγS and high Ca2+ (10-5M) resulted in irreversible thiophosphorylation of the myosin light chains and activation of a Ca2+ insensitive tension. In contrast, pretreatment with low Ca2+ (10-8M) and ATPγS results in no thiophosphorylation of the myosin light chains or irreversible activation of tension. These results are consistent with a Ca2+-sensitive myosin light chain kinase/phosphatase system being responsible for the activation of the muscle. Other agents known to have an effect upon the Ca2+-activated tension in skinned vertebrate smooth muscle fibers (trifluoperazine, catalytic subunit of the cyclic AMP-dependent protein kinase, and calmodulin) did not have an effect on myosin light chain phosphorylation or Ca2+-activated tension. These results suggest a different type of myosin light chain kinase than is found in vertebrate smooth muscle is responsible for the activation of parastichopus longitudinal body wall muscle.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0148-7280
    Keywords: spermatozoa ; flow cytometry ; DNA staining ; nuclear morphology ; ultrastructure ; mammals ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: The morphological and ultrastructural changes that occur during preparation of porcine, bovine, and murine spermatozoa for flow cytometric quantification of the relative DNA content of the X- and Y-chromosome-bearing sperm populations were examined. Ejaculated spermatozoa from the boar and bull were washed using a series of dimethyl sulfoxide (DMSO) solutions prior to fixation, whereas the epididymal mouse spermatozoa were washed only in phosphate-buffered saline (PBS). Spermatozoa from all three species were then fixed in ethanol and processed for fluorochrome staining by a treatment regimen consisting of sulfhydryl reduction and proteolysis. The processed sperm nuclei were stained for DNA with the fluorochrome, 4′-6-diamidino-2-phenylindole (DAPI) before quantification by flow cytometry. Scanning and transmission electron micrographs of sperm heads taken at various steps of the preparation and staining procedures show 1) that the rigorous washing procedure disrupted the plasma and outer acrosomal membranes, 2) that ethanol fixation resulted in removal of the outer membranes and disintegration of the nuclear envelope, and 3) that thiol and proteolysis treatment removed the remaining cellular organelles including the tail and rapidly induced partial decondensation of the tightly packed chromatin. Sequential micrographs showed that the nuclear matrix of all three species increased in thickness about twofold during the preparation and staining. Consequently, the harsh procedures currently used for quantitative staining of DNA for high-resolution flow cytometric analyses destroy most cellular organelles and thereby prevent simultaneous characterization of DNA content and other sperm cell constituents.
    Additional Material: 6 Ill.
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  • 4
    Publication Date: 2016-06-07
    Description: Results of a low speed test conducted in the Full Scale Tunnel at NASA Langley using an advanced supersonic cruise vehicle configuration are presented. These tests used a 10 percent scale model of a configuration that had demonstrated high aerodynamic performance at Mach 2.2 during a previous test program. The low speed model has leading and trailing edge flaps designed to improve low speed lift to drag ratios at high lift and includes devices for longitudinal and lateral/directional control. The results obtained during the low speed test program have shown that full span leading edge flaps are required for maximum performance. The amount of deflection of the leading edge flap must increase with C sub L to obtain the maximum benefit. Over 80 percent of full leading edge suction was obtained up to lift off C sub L's of 0.65. A mild pitch up occurred at about 6 deg angle of attack with and without the leading edge flap deflected. The pitch up is controllable with the horizontal tail. Spoilers were found to be preferable to spoiler/deflectors at low speeds. The vertical tail maintained effectiveness up to the highest angle of attack tested but the tail on directional stability deteriorated at high angles of attack. Lateral control was adequate for landing at 72 m/sec in a 15.4 m/sec crosswind.
    Keywords: AERODYNAMICS
    Type: Supersonic Cruise Res. 1979, Pt. 1; p 35-57
    Format: application/pdf
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  • 5
    Publication Date: 2019-06-28
    Description: PAN AIR is a computer program that predicts subsonic or supersonic linear potential flow about arbitrary configurations. The code's versatility and generality afford numerous possibilities for modeling flow problems. Although this generality provides great flexibility, it also means that studies are required to establish the dos and don'ts of modeling. The purpose of this paper is to describe and evaluate a variety of methods for modeling flows with PAN AIR. The areas discussed are effects of panel density, internal flow modeling, forebody modeling in subsonic flow, propeller slipstream modeling, effect of wake length, wing-tail-wake interaction, effect of trailing-edge paneling on the Kutta condition, well- and ill-posed boundary-value problems, and induced-drag calculations. These nine topics address problems that are of practical interest to the users of PAN AIR.
    Keywords: AERODYNAMICS
    Type: AIAA PAPER 83-1830
    Format: text
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  • 6
    Publication Date: 2019-06-28
    Description: Models tested in the NASA Ames 12-Foot Pressure Wind Tunnel over an angle of attack range from 0 deg to 90 deg are mounted on a floor strut that protrudes from a fairly large support bump. In high-angle-of-attack tests (angle of attack = 40 deg to 90 deg), for which the floor support was originally designed, the effects of the flow angularities produced by the bump are often negligible. This is not so for low-angle-of-attack tests (0 deg to 40 deg). Since there are no standard means for correcting test data for this bump effect, low-angle-of-attack testing with the bump is not recommended by the Ames wind-tunnel staff. This paper presents an exploratory study of a technique for correcting balance forces and experimental pressures for combined wall and bump effects. This is done by modeling the aircraft, wind-tunngl walls, and bump, with PAN AIR. The wall-and-bump-induced increments in the lift coefficient and pitching-moment coefficient predicted by PAN AIR are compared with increments obtained from the Ames 12-foot tunnel with the bump and an 8 x 12 low speed wind tunnel which has no bump.
    Keywords: AERODYNAMICS
    Type: AIAA PAPER 84-0219
    Format: text
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  • 7
    Publication Date: 2019-06-27
    Description: Measurements were made of wall pressure fluctuations under a turbulent boundary layer on the fuselage of a sailplane. Experiments with the sailplane offered a noise-free flow with a low free-stream turbulence level. In this environment the wall-pressure spectrum of a turbulent boundary layer with natural transition was found to drop off at low frequencies. Correlations between several wall-mounted microphones revealed that the large-scale motions contribute about 35% to the mean square pressure. Velocity fluctuations at several positions within and outside the boundary layer were measured and correlated with the wall pressure. It seems that the irrotational motions in the turbulent region are primarily responsible for the large-scale wall-pressure fluctuations. A time-lagged conditional correlation of the pressure was introduced to gain further insight into the pressure-producing motions.
    Keywords: AERODYNAMICS
    Type: Journal of Fluid Mechanics; 97; Mar. 25
    Format: text
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  • 8
    Publication Date: 2019-07-13
    Description: Preflight predictions of the structural temperature distributions during entry are compared with data from the initial Shuttle flight. Finite element thermal analysis programming was used to model the heat flow on Shuttle structures and actual gas properties of air were employed in the analyses of aerodynamic heating. Laminar, separated, and turbulent heat fluxes were calculated for varying locations on the craft using velocity-attitude and angle-of-attack projections taken from the nominal STS-1 trajectory. Temperature time histories of the first flight are compared with laminar and turbulent flow assumptions and an unpredicted rapid cooling 1800 sec into entry is credited to inaccurate assumptions of structural heat dissipative properties or flow conditions in that time phase of the flight; additional discrepancies in descriptions of heating of the upper fuselage are attributed to a lack of knowledge of the complex flow patterns existing over that area of the Shuttle body.
    Keywords: AERODYNAMICS
    Type: AIAA PAPER 81-2382 , Flight Testing Conference; Nov 11, 1981 - Nov 13, 1981; Las Vegas, NV
    Format: text
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  • 9
    Publication Date: 2019-07-13
    Description: PAN AIR is a computer program for predicting subsonic or supersonic linear potential flow about arbitrary configurations. It uses linear source and quadratic doublet strength distributions. These higher-order distributions have been implemented in a manner that greatly reduces the numerical stability problems that have plagued earlier attempts to make surface paneling methods work successfully for supersonic flow. PAN AIR's problem-solving capability, numerical approach, modeling features, and program architecture are described. Numerical results are presented for a variety of geometries at supersonic Mach numbers.
    Keywords: AERODYNAMICS
    Type: AIAA PAPER 81-1255 , Fluid and Plasma Dynamics Conference; Jun 23, 1981 - Jun 25, 1981; Palo Alto, CA
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  • 10
    Publication Date: 2019-07-13
    Description: A natural laminar flow airfoil has been developed as a part of the aircraft energy efficiency program. A NASA flight program incorporating this airfoil into partial wing gloves on the F-111 TACT airplane was scheduled to start in May, 1980. In support of this research effort, an extensive boundary layer stability analysis of the partial glove has been conducted. The results of that analysis show the expected effects of wing leading-edge sweep angle, Reynolds number, and compressibility on boundary layer stability and transition. These results indicate that it should be possible to attain on the order of 60% laminar flow on the upper surface and 50% laminar flow on the lower surface for sweep angles of at least 20 deg, chord Reynolds numbers of 25 x 10 to the 6th and Mach numbers from 0.81 to 0.85.
    Keywords: AERODYNAMICS
    Type: Symposium on Viscous flow drag reduction; Nov 07, 1979 - Nov 08, 1979; Dallas, TX
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