Publication Date:
1982-05-28
Description:
Adenosine triphosphate levels in erythrocytes are correlated with LDH-B genotype in Fundulus heteroclitus. Adenosine triphosphate is the fish's allosteric modifier of hemoglobin oxygen affinity. Since oxygen delivery to muscle affects swimming performance, fish of each homozygous LDH-B phenotype were swum to exhaustion at 10 degrees or 25 degrees C to determine whether in vitro differences attributed to the LDH-B allelic isozymes were manifest in vivo. At 10 degrees C, the critical swimming speed of the LDH-BaBa phenotype was 3.6 body lengths per second, whereas that of the LDH-BbBb phenotype was 4.3 body lengths per second. At 25 degrees C there were no differences between LDH-B phenotypes in erythrocyte adenosine triphosphate levels, blood oxygen affinity, or swimming performance.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉DiMichele, L -- Powers, D A -- 1-F32-GMO7889-01/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1982 May 28;216(4549):1014-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7079747" target="_blank"〉PubMed〈/a〉
Keywords:
Adenosine Triphosphate/blood
;
Animals
;
Fishes/*physiology
;
Gene Frequency
;
Isoenzymes
;
Killifishes/*physiology
;
L-Lactate Dehydrogenase/genetics/*physiology
;
Oxygen/blood
;
*Physical Exertion
;
Swimming
;
Temperature
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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