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    Phase variation: evolution of a controlling element (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-09-19
    Description: Phase variation in bacteria is regulated by homologous recombination at a specific DNA site. This recombinational event causes the inversion of a 970-base-pair DNA sequence that includes the promoter necessary for transcription of a flagellar gene. The invertible segment is flanked by two sites that are necessary for the inversion and contains a gene (hin) whose product mediates the inversion event. The hin gene shows extensive homology with the TnpR gene carried on the Tn3 transposon. It is also homologous with the gin gene carried on bacteriophage mu. These relationships suggest that the phase variation system may have evolved by the association of a transposon with a resident gene and the subsequent specialization of these elements to regulate flagellar antigen expression.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Simon, M -- Zieg, J -- Silverman, M -- Mandel, G -- Doolittle, R -- New York, N.Y. -- Science. 1980 Sep 19;209(4463):1370-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6251543" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Bacterial Proteins/*genetics ; Base Sequence ; *DNA Transposable Elements ; DNA, Bacterial/genetics ; Flagellin/*genetics ; Genes ; Recombination, Genetic ; Salmonella/*genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
    Electronic Resource
    Electronic Resource
    Simplified finite element mesh for dynamic analysis of a nuclear reactor building (1983)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 19 (1983), S. 1414-1420 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: The design of nuclear facilities requires dynamic analysis to evaluate their performance during an earthquake. In modal analysis, a method recommended for dynamic analysis by the Nuclear Regulatory Commission, the natural frequencies and mode shapes of the structure are commonly calculated using a stiffness matrix computed using the finite element method.A primary goal of this study was to design a finite element mesh, capable of modelling a reactor structure, with a minimum number of nodes and elements. This is necessary since analysis using a mesh fine enough to include all of the structural elements is not feasible because of exorbitant computer time and storage requirements. It was found that for lateral motion, a representative reactor structure could be accurately modelled using a simplified mesh with only one isoparametric quadratic quadrilateral element per floor. In this mesh essentially infinite springs must be placed between the masses at each floor level to prevent internal movements of the lumped masses within the quadratic quadrilateral elements.It was also found that a structure with rigid heavy bottom floors and a light top floor can be subjected to large displacements in the top floor during earthquakes. It was concluded that the properties of that light top floor (especially shear area) controls the value of the fundamental frequency of the building.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620190911
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  • 3
    Electronic Resource
    Electronic Resource
    2-D multiplane finite element technique for solving a class of 3-D problems (1983)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 19 (1983), S. 113-124 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A finite element technique, for efficient solution of a class of 3-D elasticity problems, is presented. In this method, standard 2-D finite elements are used along with a ‘connector’ element. An element, previously used to model material interfaces, is shown to provide the properties for use as a ‘connector’ element, if input variables are redefined. The accuracy of the technique is illustrated with a sample solution.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620190111
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