Publication Date:
1982-07-23
Description:
Two families were studied in which the same homolog of chromosome pair 10 expressed both the fragile sites on the long (q) arm at 10q23 and 10q25. Recombination between the fragile sites was observed in 3 of the 27 offspring in whom it could occur. The genetic length of chromosome between the fragile sites was 11 female centimorgans within a 95 percent probability interval of 4 to 28 centimorgans. This estimate of genetic length is comparable to those obtained with other methods.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sutherland, G R -- Baker, E -- Mulley, J C -- New York, N.Y. -- Science. 1982 Jul 23;217(4557):373-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7089572" target="_blank"〉PubMed〈/a〉
Keywords:
Chromosome Banding
;
Chromosome Fragile Sites
;
*Chromosome Fragility
;
Chromosome Mapping
;
Chromosomes, Human, 6-12 and X/*ultrastructure
;
Crossing Over, Genetic
;
Female
;
Humans
;
Karyotyping
;
Male
;
Meiosis
;
Pedigree
;
Recombination, Genetic
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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