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  • Animals  (6)
  • Female  (3)
  • GEOPHYSICS
  • American Association for the Advancement of Science (AAAS)  (8)
  • 1980-1984  (8)
  • 1965-1969
  • 1
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    Two classes of single-stranded regions in DNA from sea urchin embryos (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-02-06
    Description: Native DNA from sea urchin embryos contains single-stranded regions (gaps) of up to 3000 nucleotides. The longer gaps (more than 1400 nucleotides) are nonrandomly distributed and are rich in histone gene sequences, other moderately repetitive sequences, and polypyrimidines. The shorter gaps are associated with DNA replication. A method for isolation of the two classes of single-stranded DNA pieces is reported.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wortzman, M S -- Baker, R F -- New York, N.Y. -- Science. 1981 Feb 6;211(4482):588-90.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7455698" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Differentiation ; *DNA Replication ; DNA, Single-Stranded/*analysis/genetics ; Genes ; Histones/*genetics ; Recombination, Genetic ; Sea Urchins/*genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Adaptive changes of the vestibulo-ocular reflex in flatfish are achieved by reorganization of central nervous pathways (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-08-19
    Description: Flatfish provide a natural model for the study of adaptive changes in the vestibulo-ocular reflex system. During metamorphosis their vestibular and oculomotor coordinate systems undergo a 90 degree relative displacement. As a result, during swimming movements different types of compensatory eye movements are produced before and after metamorphosis by the same vestibular stimulation. Intracellular staining of central nervous connections in the flatfish with horseradish peroxidase revealed that in postmetamorphic fish secondary horizontal semicircular canal neurons contact vertical eye muscle motoneuron pools on both sides of the brain via pathways that are absent in all other vertebrates studied.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Graf, W -- Baker, R -- 13742/PHS HHS/ -- New York, N.Y. -- Science. 1983 Aug 19;221(4612):777-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6603656" target="_blank"〉PubMed〈/a〉
    Keywords: Adaptation, Physiological ; Animals ; Fishes/anatomy & histology/*physiology ; Metamorphosis, Biological ; Neuronal Plasticity ; Oculomotor Muscles/*physiology ; Vestibule, Labyrinth/innervation/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Narcolepsy: biogenic amine deficits in an animal model (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-05-06
    Description: Concentrations of biogenic amine metabolites in discrete brain areas differed significantly between dogs with genetically transmitted narcolepsy and age- and breed-matched controls. Dopamine and 3,4-dihydroxyphenylacetic acid were consistently elevated in the brains of narcoleptic animals, while homovanillic acid was not. Narcoleptic animals consistently exhibited lower utilization of dopamine and higher intraneuronal degradation of dopamine but no uniform decrease in serotonin utilization. Hence neuropathology appears to be associated with genetically transmitted canine narcolepsy. The data indicate a nonglobal depression of dopamine utilization or turnover or both.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mefford, I N -- Baker, T L -- Boehme, R -- Foutz, A S -- Ciaranello, R D -- Barchas, J D -- Dement, W C -- MH 05804/MH/NIMH NIH HHS/ -- MH 23861/MH/NIMH NIH HHS/ -- NS 13211/NS/NINDS NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1983 May 6;220(4597):629-32.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6188216" target="_blank"〉PubMed〈/a〉
    Keywords: 3,4-Dihydroxyphenylacetic Acid/analysis ; Animals ; *Brain Chemistry ; *Disease Models, Animal ; Dogs ; Dopamine/analysis ; Epinephrine/analysis ; Homovanillic Acid/analysis ; Humans ; Hydroxyindoleacetic Acid/analysis ; Narcolepsy/*physiopathology ; Norepinephrine/analysis ; Serotonin/analysis ; Sleep, REM/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
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    Goal orientation by blindfolded humans after long-distance displacement: possible involvement of a magnetic sense (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-10-31
    Description: A wide range of animals are able to orient toward home when subjected to displacement-release experiments. When comparable experiments are performed on blindfolded humans, a similar ability emerges. Such goal-orientation does not result from following the complete journey on a mental map, nor is it influenced by cloud cover. Bar magnets worn on the head do seem to exert an influence.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Baker, R R -- New York, N.Y. -- Science. 1980 Oct 31;210(4469):555-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7423208" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Female ; Humans ; Magnetics ; Male ; Orientation/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Mass mortality of harbor seals: pneumonia associated with influenza A virus (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-02-26
    Description: More than 400 harbor seals, most of them immature, died along the New England coast between December 1979 and October 1980 of acute pneumonia associated with influenza virus, A/Seal/Mass/1/180 (H7N7). The virus has avian characteristics, replicates principally in mammals, and causes mild respiratory disease in experimentally infected seals. Concurrent infection with a previously undescribed mycoplasma or adverse environmental conditions may have triggered the epizootic. The similarities between this epizootic and other seal mortalities in the past suggest that these events may be linked by common biological and environmental factors.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Geraci, J R -- St Aubin, D J -- Barker, I K -- Webster, R G -- Hinshaw, V S -- Bean, W J -- Ruhnke, H L -- Prescott, J H -- Early, G -- Baker, A S -- Madoff, S -- Schooley, R T -- AI02649/AI/NIAID NIH HHS/ -- AI16841/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1982 Feb 26;215(4536):1129-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7063847" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Disease Outbreaks/*veterinary ; Influenza A virus/isolation & purification ; Orthomyxoviridae Infections/*veterinary ; Pinnipedia/*microbiology ; Pneumonia/*veterinary ; Seals, Earless/*microbiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
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    Diphenylhydantoin: an alternative ligand of a glucocorticoid receptor affecting prostaglandin generation in A/J mice (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-12-24
    Description: Evidence for the binding of 5,5-diphenylhydantoin and glucocorticoids to a common receptor is presented for pulmonary and hepatic cytosols and thymocytes of A/J female mice. The 5,5-diphenylhydantoin-protein complex is absorbed by DNA cellulose, and is incorporated into nuclei, 5,5-Diphenylhydantoin, like glucocorticoids, inhibits the production of prostaglandins in thymocytes. Thus a common receptor is probably responsible for the inhibitory and teratogenic effects of these drugs.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Katsumata, M -- Gupta, C -- Baker, M K -- Sussdorf, C E -- Goldman, A S -- DE-4622/DE/NIDCR NIH HHS/ -- DE-5041/DE/NIDCR NIH HHS/ -- DE-5592/DE/NIDCR NIH HHS/ -- New York, N.Y. -- Science. 1982 Dec 24;218(4579):1313-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6897299" target="_blank"〉PubMed〈/a〉
    Keywords: 6-Ketoprostaglandin F1 alpha/biosynthesis ; Animals ; Binding, Competitive ; Cleft Palate/chemically induced ; Dexamethasone/metabolism ; Liver/metabolism ; Lung/metabolism ; Mice ; Phenytoin/*metabolism ; Prostaglandins/*biosynthesis ; Receptors, Glucocorticoid/*metabolism ; Receptors, Steroid/*metabolism ; Thromboxane B2/biosynthesis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
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    Genetic length of a human chromosomal segment measured by recombination between two fragile sites (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-07-23
    Description: Two families were studied in which the same homolog of chromosome pair 10 expressed both the fragile sites on the long (q) arm at 10q23 and 10q25. Recombination between the fragile sites was observed in 3 of the 27 offspring in whom it could occur. The genetic length of chromosome between the fragile sites was 11 female centimorgans within a 95 percent probability interval of 4 to 28 centimorgans. This estimate of genetic length is comparable to those obtained with other methods.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sutherland, G R -- Baker, E -- Mulley, J C -- New York, N.Y. -- Science. 1982 Jul 23;217(4557):373-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7089572" target="_blank"〉PubMed〈/a〉
    Keywords: Chromosome Banding ; Chromosome Fragile Sites ; *Chromosome Fragility ; Chromosome Mapping ; Chromosomes, Human, 6-12 and X/*ultrastructure ; Crossing Over, Genetic ; Female ; Humans ; Karyotyping ; Male ; Meiosis ; Pedigree ; Recombination, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
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    A gene controlling condensation of heterochromatin in Drosophila melanogaster (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-07-01
    Description: A temperature-sensitive lethal mutant of Drosophila melanogaster was used to identify an essential cell cycle function that is necessary for the mitotic condensation of heterochromatic but not of euchromatic portions of the genome. This mutant is an allele at a locus (mus-101) identified earlier by the use of mutagen-sensitive mutants. The data suggest that the mutagen-sensitive and repair-defective phenotypes of viable mus-101 mutants result from a disruption in chromosome organization.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gatti, M -- Smith, D A -- Baker, B S -- GM23345/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1983 Jul 1;221(4605):83-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6407113" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Cycle ; Chromosomes/ultrastructure ; Drosophila melanogaster ; Female ; *Genes ; Heterochromatin/*genetics/physiology ; Male ; Mutation
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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